Mircea Focsa

University Of Medicine And Pharmacy Timisoara, Medical Informatics and Biostatistics, Faculty Member

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Dr. Mircea Adrian Focsa is an Associate Professor of Medical Informatics and Biostatistics at the Department of Medical Informatics, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania. He graduated from medical school in Timisoara in 1995, earned an MSc in Medical Informatics from Cluj Napoca in 2001, and became a Public Health and Healthcare Management specialist in 2008. Dr. Focsa completed his PhD in 2007 with a dissertation on "Quality Certification of EHR Systems."

In 2008, Dr. Focsa joined an international team to develop knowledge-based clinical information systems, coordinate ontology development, and implement medical algorithms. He led the interoperability group within the Theme Advisory Committee for Health Services (CCTSS) of the Romanian Ministry of Health in 2012. As a founding member and President of the Prorec Romania Association, he contributes to the Eurorec Institute's efforts to promote the adoption of certified EHR systems across Europe.

Dr. Focsa recently facilitated the implementation of Romania's first Patient Recruitment System for clinical studies, connecting to Clinerion's global network of hospitals. He has actively participated in numerous European and national-funded projects related to eHealth and eLearning, serving as a European expert for eHealth projects under programs such as COST, CEF-Telecom, and Horizon. He is also a member of the Journal of Medical Internet Research Editorial Board.

Throughout his career, Dr Focsa has been involved in various clinical research projects in specialities, including gastroenterology, neurology, cardiology, and public health. He has published extensively, with dozens of peer-reviewed research articles, book chapters, conference papers, and presentations, amassing over 800 citations.
Supervisors: Gheorghe Ioan Mihalas
Phone: 0040723281511

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[The electroacupuncture in patients recently operated for peripheral arterial disease. A comparative study of the two electrostimulation techniques]

PubMed, Mar 3, 2010

Possible hemodynamic effects of electro acupuncture (A), by two electro stimulation techniques, w... more Possible hemodynamic effects of electro acupuncture (A), by two electro stimulation techniques, were studied at patients with femuro - popliteal bypass revascularization. MMATERIAL AND METHOD:In a prospective study, we evaluated two EA techniques, by calculating the ankle-brachial index (ABI) and by estimating the pain with Numeric Rating Scale (NRS: 0 - 10). The patients were grouped in lot A (30 patients) and B (50 patients) according with the EA technique used. In both lots were used the same acupuncture points (acupoint): Pc6, P9, St36 and Sp6. These acupoints are adjacent to peripheral nerves median, radial, peroneal and safenous nerve. Needles, after insertion, were kept in place for 30 minutes. The electro stimulation (2 Hz) was only for 2 minutes in the lot A and for 30 minutes in the lot B. Results: The blood pressure data and ABI shows a significant increase of ABI (between 0.033 and 0.052) after EA at 5 minutes in the both lots (p < 0.05). At 30 minutes, ABI is increased in lot B, but in the lot A the ABI is elevated only at the non surgical leg (p < 0.05). The decrease of pain post EA is better in the lot B (NRS: initially 2.48--post EA pain decreased to 1.46 and remained 1.66 at 2 hours; p < 0.001), than lot A. Conclusions: The electro stimulation of certain acupoints, at the operated peripheral arterial disease patients, interfere with tissular perfusion and increase temporally ABI. The pain is diminished more significantly by the 30 minutes electro stimulating technique.

The quality of the fragment obtained by liver biopsy for staging chronic hepatitis

PubMed, Sep 1, 2007

The aim of our paper was to assess the quality of the liver fragment obtained by liver biopsy for... more The aim of our paper was to assess the quality of the liver fragment obtained by liver biopsy for staging chronic hepatitis. Material and method: We analyzed retrospectively 250 echoassisted percutaneous liver biopsies (LB) concerning the length of the fragment and the mean number of portal spaces. We used Menghini modified needles 1.4 and 1.6 mm in diameter and the LBs were performed by the same senior hepatologist. Results: The indications for the LB were represented by: chronic hepatitis C in 69 % (172 cases), chronic hepatitis B in 17 % (43 cases), chronic hepatocytolysis in 10% (25 cases), primary billiary cirrhosis in 1.5% (4 cases), chronic B+C hepatitis in 3 cases, autoimmune chronic hepatitis in 2 cases and Wilson's disease in 1 case. From the 250 LBs, in 87% of cases (217 patients) the liver sample had 8-10 portal spaces ("good fragment") and in 69% of cases (173 patients) the liver sample had at least 11 portal spaces ("very good fragment"). In 13% of the cases (33 liver biopsies) the histological sample was suboptimal, less than 8 portal spaces. In 1.6% of the cases (4 biopsies), the liver sample was not adequate for the diagnosis (less than 4 portal spaces), so that we had to perform a second biopsy (in another session). In 88% cases (219 subjects), the length of the liver fragment obtained was longer than 2 cm and only in 12% of cases (31 patients) the fragment was smaller than 2 cm. The median length of the fragment obtained by LB in our department was 30.8 +/- 8.7 mm, and the mean number of portal spaces was 14.9 +/- 7.09. Conclusion: In experienced hands, percutaneous liver biopsy can obtain "good" histological material in the vast majority of cases.

Acoustic Radiation Force Impulse Elastography as Compared to Transient Elastography and Liver Biopsy in Patients with Chronic Hepatopathies

Ultraschall in Der Medizin, Jul 5, 2010

To compare two methods of noninvasive assessment: transient elastography (TE) and acoustic radiat... more

S2084 TRANSIENT ELASTOGRAPHY (FibroScan®) As Compared to Real-Time Elastography (Siemens) in Patients with Chronic Hepatopathies

Gastroenterology, May 1, 2009

No abstract is available. To read the body of this article, please view the PDF online. ... © 200... more

Predictive factors for severe evolution in acute pancreatitis and a new score for predicting a severe outcome

PubMed, 2013

Background: Acute pancreatitis (AP) is an acute inflammation of the pancreas with an unpredictabl... more Background: Acute pancreatitis (AP) is an acute inflammation of the pancreas with an unpredictable evolution. The aim of this study was to assess the factors associated with severe evolution of AP and to create a new score for predicting a severe outcome. Methods: The initial group included 334 patients hospitalized in 2006-2009. The validation group included 195 patients admitted in 2010-2011. AP was classified according to the Atlanta criteria. Results: In the initial group, C-reactive protein (CRP), creatinine, white blood count, body mass index (BMI), age and male gender were correlated with severe evolution of AP. Using only parameters available in emergency, by multiple regression analysis we obtained in the initial group the following score for predicting severe evolution of AP: Prediction pancreatic severity I score (PPS I score) = -1.038 + 0.119 × creatinine (mg/dL) + 0.012 × BMI (kg/m²) + 0.027xwhite blood count/1000 (cells/mm³) + 0.195 × gender (1-women, 2-men) + 0.005 × age (years). For a cut-off value >0.325, PPS I score had 71.8% accuracy (AUC=0.790) for predicting a severe evolution of AP. In the validation group the accuracy was 71.7%. Since CRP was proven to be a good predictor of severe evolution in AP, we calculated another score, PPS II, obtained using PPS I and CRP: PPS II score = -0.192 + 0.760 x PPS I + 0.003 x CRP (mg/L). For a cut-off value >0.397, PPS II score had 87.1% accuracy (AUROC=0.942) in the initial group and 75.3% accuracy in the validation group for predicting severe AP. Conclusions: PPS I and especially PPS II score are accurate predictors of severe outcome in patients with AP.

1196: Assessment of Liver Fibrosis by Real Time SonoElastography (Hitachi) as Compared to Liver Biopsy and Transient Elastography

Ultrasound in Medicine and Biology, Aug 1, 2009

most affected site and the main lesions are lymph nodes, abscesses, lipoma, lymphangiomas and thy... more most affected site and the main lesions are lymph nodes, abscesses, lipoma, lymphangiomas and thyroglossal cyst. In the case of abscesses there is a fluid collection with thick walls and debris. The carotid space shows many lesions, such as: lymph nodes, paragangliomas and internal jugular vein trombosis. The paragangliomas are seen as solid masses.The posterior triangle is the site of many lesions such as: lymph nodes, lymphangiomas, haemangiomas, lipoma and third branchial cleft cyst. Conclusion: The ultrasound is an excellent method for evaluating head and masses.

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