Papers by Amanda da Silva Silveira
Fibrinogen-related proteins (FREPs) comprise a large family of microbial recognition proteins inv... more Fibrinogen-related proteins (FREPs) comprise a large family of microbial recognition proteins involved in
many biological functions in both vertebrate and invertebrate animals. By taking advantage of publicly
accessible databases, we have identified a FREP-like homolog in the most cultivated penaeid shrimp,
Litopenaeus vannamei (LvFrep). The obtained sequence showed a conserved fibrinogen-related domain
(FReD) and displayed significant similarities to FREP-like proteins from other invertebrates and to ficolins
from crustaceans. The expression of LvFrep appeared to be limited to circulating hemocytes. Interestingly,
LvFrep gene expression was induced in shrimp hemocytes only in response to a Vibrio infection but not to the White spot syndrome virus (WSSV). Moreover, LvFrep transcript levels were detected early in fertilized eggs, suggesting the participation of this immune-related gene in the antimicrobial defenses during shrimp development
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Papers by Amanda da Silva Silveira
many biological functions in both vertebrate and invertebrate animals. By taking advantage of publicly
accessible databases, we have identified a FREP-like homolog in the most cultivated penaeid shrimp,
Litopenaeus vannamei (LvFrep). The obtained sequence showed a conserved fibrinogen-related domain
(FReD) and displayed significant similarities to FREP-like proteins from other invertebrates and to ficolins
from crustaceans. The expression of LvFrep appeared to be limited to circulating hemocytes. Interestingly,
LvFrep gene expression was induced in shrimp hemocytes only in response to a Vibrio infection but not to the White spot syndrome virus (WSSV). Moreover, LvFrep transcript levels were detected early in fertilized eggs, suggesting the participation of this immune-related gene in the antimicrobial defenses during shrimp development
many biological functions in both vertebrate and invertebrate animals. By taking advantage of publicly
accessible databases, we have identified a FREP-like homolog in the most cultivated penaeid shrimp,
Litopenaeus vannamei (LvFrep). The obtained sequence showed a conserved fibrinogen-related domain
(FReD) and displayed significant similarities to FREP-like proteins from other invertebrates and to ficolins
from crustaceans. The expression of LvFrep appeared to be limited to circulating hemocytes. Interestingly,
LvFrep gene expression was induced in shrimp hemocytes only in response to a Vibrio infection but not to the White spot syndrome virus (WSSV). Moreover, LvFrep transcript levels were detected early in fertilized eggs, suggesting the participation of this immune-related gene in the antimicrobial defenses during shrimp development