Uroporfirinogenska dekarboksilaza
Izgled
Uroporfirinogenska dekarboksilaza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.1.1.37 | ||||||||
CAS broj | 9024-70-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Uroporfirinogenska dekarboksilaza (EC 4.1.1.37, uroporfirinogen III dekarboksilaza, porfirinogenska karboksi-lijaza, porfirinogenska dekarboksilaza, uroporfirinogen-III karboksilijaza) je enzim sa sistematskim imenom uroporfirinogen-III karboksilijaza (formira koproporfirinogen-III).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- uroporfirinogen III koproporfirinogen III + 4 CO2
Ovaj enzim deluje na brojne porfirinogene.
- ↑ Mauzerall, D. and Granick, S. (1958). „Porphyrin biosynthesis in erythrocytes. III. Uroporphyrinogen and its decarboxylase”. J. Biol. Chem. 232: 1141-1162. PMID 13549492.
- ↑ Tomio, J.M., Garcia, R.C., San Martin de Viale, L.C. and Grinstein, M. (1970). „Porphyrin biosynthesis. VII. Porphyrinogen carboxy-lyase from avian erythrocytes. Purification and properties”. Biochim. Biophys. Acta 198: 353-363. PMID 4984554.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.