Papers by Jawayria najeeb
Materials chemistry and physics, Jul 1, 2024
Journal of Cleaner Production, Dec 31, 2023
Current Pharmaceutical Design
Background:: In the case of COVID-19 patients, it has been observed that the immune system of the... more Background:: In the case of COVID-19 patients, it has been observed that the immune system of the infected person exhibits an extreme inflammatory response known as cytokine release syndrome (CRS) where the inflammatory cytokines are swiftly produced in quite large amounts in response to infective stimuli. Numerous case studies of COVID-19 patients with severe symptoms have documented the presence of higher plasma concentrations of human interleukin-6 (IL-6), which suggests that IL-6 is a crucial factor in the pathophysiology of the disease. In order to prevent CRS in COVID-19 patients, the drugs that can exhibit binding interactions with IL-6 and block the signaling pathways to decrease the IL-6 activity may be repurposed. Methods:: This research work focused on molecular docking-based screening of the drugs celecoxib (CXB) and dexamethasone (DME) to explore their potential to interact with the binding sites of IL-6 protein and reduce the hyper-activation of IL-6 in the infected pe...
Zeitschrift für Physikalische Chemie
In this work, Raphanus caudatus (radish pod) leaves biomass was used as an adsorbent for the remo... more In this work, Raphanus caudatus (radish pod) leaves biomass was used as an adsorbent for the removal of crystal violet (CV) and Rhodamine B (RhB) dye from water medium. Adsorption process was performed by changing different adsorption factors such as adsorbent dose, agitation time, adsorbate concentration, pH and temperature to get maximum removal of dyes. It was observed that R. caudatus leaves biomass showed 48.7 and 19.0 mg/g value of adsorption capacity for CV and RhB dyes, respectively. High adsorption capacity value for CV was observed due to its less complex structure and small sized molecules as compared to the RhB dye molecules. Dyes removal process followed pseudo second order with the values of regression factor (R 2) found as 0.999 and 0.998 for CV and RhB, respectively. Values of R 2 were found as 0.999 and 0.998 for the removal of CV and RhB respectively while following the Langmuir adsorption isotherm model. It illustrates the single layered dye molecules adsorption o...
Antioxidants, Jun 20, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Environmental Science and Pollution Research, May 15, 2020
Extraction of toxic heavy metal ions from aqueous medium using poly(N-isopropylmethacrylamide-acr... more Extraction of toxic heavy metal ions from aqueous medium using poly(N-isopropylmethacrylamide-acrylic acid) (P(NiPmA-Ac)) microgels as adsorbent has been investigated in present study. P(NiPmA-Ac) microgel particles were prepared by free radical precipitation polymerization in aqueous medium. Morphology and size of the prepared microgel particles was investigated by transmission electron microscopy (TEM). The Fourier transform infrared (FT-IR) analysis of pure and metal ion–loaded microgel particles was performed to confirm the presence of various functionalities of microgel particles and their interaction with metal ions extracted from aqueous medium. Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) were used to investigate the thermal stability and thermal behavior of pure and metal ion–loaded microgel particles. Contents of metal ions loaded into microgel particles were determined by TGA analysis. It was observed that P(NiPmA-Ac) particles have a potential to extract Cu 2+ and Co 2+ ions from aqueous medium. The Freundlich adsorption isotherm model best interprets the adsorption process as compared with the Langmuir model. Value of R 2 according to the Freundlich adsorption isotherm was found to be 0.994 and 0.993 for Cu 2+ and Co 2+ ions, respectively. Adsorption process was followed by pseudo second order kinetics for Cu 2+ and Co 2+ ions with R 2 values of 0.999 for both metal ions. Thermodynamic study showed that adsorption process was spontaneous, feasible, and endothermic in nature. Entropy was decreased at adsorbate-adsorbent interface during adsorption process. Adsorbent was recycled and reused for removal of Cu 2+ ions, and adsorption efficiency was found to be maintained up to three cycles. Microgel particles also have ability to extract Cu 2+ ions efficiently from electroplating wastewater. Graphical abstract
Chemical Physics Letters, 2021
Abstract Poly (N-isopropylacrylamide-2-hydroxy ethyl methacrylate-acrylic acid) [P(NHA)] colloida... more Abstract Poly (N-isopropylacrylamide-2-hydroxy ethyl methacrylate-acrylic acid) [P(NHA)] colloidal particles of core-shell morphology were obtained by free radical emulsion polymerization. Loading of Silver nanoparticles within P(NHA) colloidal particles was attained by in-situ reduction. P(NHA) and Ag-P(NHA) particles were characterized by UV-Vis and TEM. For probing catalytic ability of Ag-P(NHA) hybrid particles, catalytic reduction of 4-Nitroaniline (4-NA) was carried out as an exemplary reaction. Ag-P(NHA) hybrid particles served as an exceptional nano-catalyst for reduction of 4-NA. Comparison of current study with academic literature proves that our system provides rapid and simple approach for efficient and cost-effective reduction of 4-NA in aqueous condition.
Reactive & Functional Polymers, Nov 1, 2018
Abstract In this work, poly(N-isopropylmethacrylamide-co-acrylic acid) [p(NIPMAM-co-AAc)] microge... more Abstract In this work, poly(N-isopropylmethacrylamide-co-acrylic acid) [p(NIPMAM-co-AAc)] microgels were synthesized by using precipitation polymerization method. Silver nanoparticles (AgNPs) were uniformly dispersed inside the sieves of the engineered microgels by in situ reduction method. Both microgels and hybrid microgels were characterized by Transmission Electron Microscopy (TEM), Ultraviolet-Visible (UV–Vis) spectroscopy and Fourier Transform Infrared (FTIR) spectroscopy. The average diameter of the fabricated AgNPs was found to be 15 nm. The catalytic reduction of 2-Nitroaniline (2-NA) was used as model reaction to investigate the catalytic activity of the hybrid microgels. The value of apparent rate constant (kapp) for catalytic reduction of 2-NA was determined using pseudo first order kinetic model spectrophotometrically under various conditions of reaction to explore the mechanism of catalysis. The kinetic data reveals that catalytic reduction of 2-NA occurs according to Langmuir-Hinshelwood mechanism. The comparison of present study with previous literature makes our system a facile, efficient and stable catalyst for rapid and economical reduction of 2-NA in aqueous medium.
DESALINATION AND WATER TREATMENT, 2022
The Salvadora persica (Pilu) a cost effective material, is recently being used as adsorbent for t... more The Salvadora persica (Pilu) a cost effective material, is recently being used as adsorbent for the removal of highly toxic Cu(II) ions from polluted water. In this study, three comparative studies, untreated adsorbent (UTSP) and microwave and activating agents mediated activated adsorbent (ACSP) were investigated simultaneously and parallels were drawn between them for validating removal efficiency. Characterization analysis including Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) have been utilized for adsorbent. Factors affecting the adsorption of copper including pH, adsorbent dose, exposure time, and the temperature were investigated. Results showed that ACSP required less extreme conditions for effective working as compared to UTSP. Kinetic studies showed this adsorption reaction was endothermic, feasible, and spontaneous. Additionally, the results clearly showed that both adsorbents exhibited the best correlation with the Langmuir and Freundlich model of adsorption. Hence, a novel, economical and facile biomaterial has been reported in this study for Cu(II) ions removal from aqueous media.
Journal of Cleaner Production, Sep 1, 2022
International Journal of Environmental Science and Technology, Aug 3, 2022
Renewable Energy, May 1, 2021
Abstract Current study was designed for developing the novel nano-biocatalyst (Lipase-PDA-TiO2 NP... more Abstract Current study was designed for developing the novel nano-biocatalyst (Lipase-PDA-TiO2 NPs) for enzymatic transesterification of Jatropha curcas seed oil (JCSO). The TiO2 NPs were prepared by the hydrothermal method and were afterward modified by the polydopamine (PDA) polymer. The synthesized nanomaterial was characterized by SEM, FTIR, XRD and energy dispersive X-ray spectroscopy. Lipase activity assay was used to check the stability of immobilized enzyme under varying conditions of pH and temperature. Transesterification of JCSO using Lipase-PDA-TiO2 NPs catalyst was optimized by response surface methodology (RSM). Optimum biodiesel yield (92%) was achieved by carrying out the transesterification process for 30 h at 37 °C temperature with 10% nano-biocatalyst concentration, 6:1 methanol:oil ratio and 0.5% water content. On the basis of model significance, R2 value, lack of fit test and predicted vs. actual values, quadratic model was selected as the best fitted model. The FTIR technique was utilized to monitor the transesterification process. The comparison of the physiochemical characteristics of the synthesized biodiesel with the international standard for bio-fuel affirms that the transesterification of JCSO in the presence of the nano-biocatalyst provides an effective alternative for the production of biodiesel.
ChemistrySelect, Apr 1, 2021
Recently, significant attention and effort have been given to the synthesis of nanomaterials (NMs... more Recently, significant attention and effort have been given to the synthesis of nanomaterials (NMs) by utilizing numerous conventional and advanced methodologies owing to its various applications in different fields of life. The green methodology is preferred over other approaches because of the advantages of cost‐effectiveness, environment friendliness, and non‐toxic nature of the utilized biogenic materials. This review summarizes and organizes the documented case studies presented in the last five years i. e. 2017–2021 that use the green chemistry approach for the production of NMs into the two broad categories of plant based NMs and microorganisms based NMs. Furthermore, the fundamentals involved in this production process such as optimization of the synthetic process, mechanism involved in the production of NMs owing to the selected biogenic system, and the extraction techniques utilized for the synthesis of the plant/biogenic extracts are also discussed in detail in this review. We believe that this review will highlight some critical practices and advancements which must be taken into consideration beforehand by the new/working scholars exploring the field of green chemistry for the production of NMs.
International Journal of Environmental Science and Technology
Inorganic Chemistry Communications
Journal of Cleaner Production
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Papers by Jawayria najeeb
change. Current resource estimation is the need of hour for sustainable water planning and management.
It will in turn help design, implement and observe the efficiency of programs of water management,
protection and conservation. Therefore, quantitative ground water assessment of Data Ganj Bakhsh
Town, of metropolitan city Lahore was conducted. For this purpose, Surfer 8.0 and GIS were used to
discover the fluctuations in ground water table for period 2004-2014.The study indicated the alarming
depletion of the ground water as average depth of it has declined to 10m in study area. To stabilize the
water table, measures such as artificial recharge, introduction of green belts, minimal abstraction, control
and shifting of population, are suggested.