(Q80489191)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

review article

1 reference

title

Histone deacetylase inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Paul A Marks

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Victoria M Richon

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Thomas Miller

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

William Kevin Kelly

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

1 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

Advances in Cancer Research

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

91

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

137-168

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

Deciphering the transcriptional histone acetylation code for a human gene

1 January 2020

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7 January 2021

Histone Deacetylase Inhibitors: From Chromatin Remodeling to Experimental Cancer Therapeutics

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Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2.

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7 January 2021

Antineoplastic action of 5-aza-2'-deoxycytidine and phenylbutyrate on human lung carcinoma cells

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7 January 2021

Novel Hydroxamate and Anilide Derivatives as Potent Histone Deacetylase Inhibitors: Synthesis and Antiproliferative Evaluation

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7 January 2021

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

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7 January 2021

Phase II study of phenylacetate in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report.

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7 January 2021

Expression profile of histone deacetylase 1 in gastric cancer tissues.

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7 January 2021

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

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7 January 2021

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 2.

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7 January 2021

Histone deacetylases, transcriptional control, and cancer

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7 January 2021

Histone Deacetylase Inhibitors: The Abbott Experience

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7 January 2021

Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5

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7 January 2021

HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis

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7 January 2021

Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling

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7 January 2021

Histone deacetylases (HDACs): characterization of the classical HDAC family

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7 January 2021

Role of histone deacetylases in acute leukemia

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7 January 2021

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

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7 January 2021

Isolation and characterization of a novel class II histone deacetylase, HDAC10

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7 January 2021

Binary switches and modification cassettes in histone biology and beyond.

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7 January 2021

Trifluoromethyl ketones as inhibitors of histone deacetylase

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7 January 2021

Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions

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7 January 2021

Cloning and functional characterization of HDAC11, a novel member of the human histone deacetylase family

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7 January 2021

Mutations truncating the EP300 acetylase in human cancers

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7 January 2021

Conjunction dysfunction: CBP/p300 in human disease.

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7 January 2021

Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells

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7 January 2021

The human histone deacetylase family

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7 January 2021

Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1

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7 January 2021

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

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7 January 2021

Activation of the mouse histone deacetylase 1 gene by cooperative histone phosphorylation and acetylation

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7 January 2021

HDAC6 is a microtubule-associated deacetylase

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7 January 2021

The N-CoR/histone deacetylase 3 complex is required for repression by thyroid hormone receptor

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7 January 2021

Translating the Histone Code

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7 January 2021

Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

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7 January 2021

The fundamental role of epigenetic events in cancer

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7 January 2021

Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor α

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7 January 2021

Histone deacetylase inhibitors: from target to clinical trials

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7 January 2021

Functional significance of histone deacetylase diversity

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7 January 2021

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

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7 January 2021

Oxamflatin is a novel antitumor compound that inhibits mammalian histone deacetylase

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7 January 2021

Acetylation: a regulatory modification to rival phosphorylation?

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7 January 2021

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

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7 January 2021

Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases

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7 January 2021

The many faces of histone lysine methylation

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7 January 2021

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression

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7 January 2021

The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene.

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7 January 2021

Histone acetyltransferases and deacetylases in the control of cell proliferation and differentiation

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7 January 2021

Crystal structure of the nucleosome core particle at 2.8 Å resolution

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7 January 2021

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

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7 January 2021

MyoD is functionally linked to the silencing of a muscle-specific regulatory gene prior to skeletal myogenesis

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7 January 2021

Histone deacetylases and cancer: causes and therapies

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7 January 2021

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7 January 2021

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

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7 January 2021

Quantification of histone acetyltransferase and histone deacetylase transcripts during early bovine embryo development.

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7 January 2021

Control of muscle development by dueling HATs and HDACs

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7 January 2021

Signaling chromatin to make muscle

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7 January 2021

Histone Deacetylase Inhibitors

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7 January 2021

Defect of histone acetyltransferase activity of the nuclear transcriptional coactivator CBP in Rubinstein-Taybi syndrome

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7 January 2021

Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

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7 January 2021

Senescence and epigenetic dysregulation in cancer

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7 January 2021

The histone deacetylase 9 gene encodes multiple protein isoforms

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7 January 2021

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

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7 January 2021

The diversity of acetylated proteins

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7 January 2021

Chronic oral administration of CI-994: a phase 1 study

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7 January 2021

Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate

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7 January 2021

Deacetylase activity is required for recruitment of the basal transcription machinery and transactivation by STAT5.

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7 January 2021

Using cancer genetics to guide the selection of anticancer drug targets

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7 January 2021

The Discovery of NVP-LAQ824: From Concept to Clinic

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7 January 2021

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects

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7 January 2021

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

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7 January 2021

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

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7 January 2021

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

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7 January 2021

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

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7 January 2021

Autoregulation of mouse histone deacetylase 1 expression

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7 January 2021

Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities.

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7 January 2021

Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression

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7 January 2021

Association of histone deacetylase with COUP-TF in tumorigenic Ad12-transformed cells and its potential role in shut-off of MHC class I transcription

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7 January 2021

An increasingly complex code

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7 January 2021

Phase I study of phenylacetate administered twice daily to patients with cancer

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7 January 2021

Histone acetylation and disease

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7 January 2021

Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain

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7 January 2021

Histone deacetylases in fungi: novel members, new facts

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7 January 2021

Regulation of histone deacetylase 2 by protein kinase CK2.

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7 January 2021

Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-erbA yields a chromatin infrastructure-dependent transcriptional repression pathway

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7 January 2021

Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

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7 January 2021

Histone acetylation and the cell-cycle in cancer

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7 January 2021

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

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7 January 2021

Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.

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7 January 2021

Tumor cell-selective cytotoxicity by targeting cell cycle checkpoints.

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7 January 2021

Dynamics of histone acetylation in vivo. A function for acetylation turnover?

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7 January 2021

Histone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-I

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7 January 2021

Deviant nucleosomes: the functional specialization of chromatin

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7 January 2021

Interaction of histone acetylases and deacetylases in vivo

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7 January 2021

BRCA1 interacts with components of the histone deacetylase complex

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7 January 2021

Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1

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7 January 2021

From discovery to the coming generation of histone deacetylase inhibitors

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7 January 2021

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228

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7 January 2021

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

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7 January 2021

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

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7 January 2021

Frequent mutations in the ligand-binding domain of PML-RARalpha after multiple relapses of acute promyelocytic leukemia: analysis for functional relationship to response to all-trans retinoic acid and histone deacetylase inhibitors in vitro and in v

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7 January 2021

Histone deacetylase 4 associates with extracellular signal-regulated kinases 1 and 2, and its cellular localization is regulated by oncogenic Ras

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7 January 2021

Acetylation control of the retinoblastoma tumour-suppressor protein

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7 January 2021

10.1016/S0065-230X(04)91004-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15327890%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference