(Q34801751)

4 August 2017

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title

Senescence and epigenetic dysregulation in cancer (English)

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4 August 2017

5

Richard G Pestell

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4 August 2017

Peter Neumeister

1

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4 August 2017

Chris Albanese

series ordinal

2

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4 August 2017

Beate Balent

series ordinal

3

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4 August 2017

John Greally

series ordinal

4

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4 August 2017

publication date

1 November 2002

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International Journal of Biochemistry & Cell Biology

4 August 2017

published in

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4 August 2017

volume

34

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4 August 2017

issue

11

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4 August 2017

page(s)

1475-1490

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The serial cultivation of human diploid cell strains

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Senescence as a mode of tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Epigenetics: regulation through repression

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Replicative senescence: an old lives' tale?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Human skin fibroblasts in vitro differentiate along a terminal cell lineage

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The relationship between in vitro cellular aging and in vivo human age

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Reversible cellular senescence: implications for immortalization of normal human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Cell death: the significance of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Aging. When do telomeres matter?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Cellular senescence: mitotic clock or culture shock?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The role of senescence and immortalization in carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomerase and human tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomere length regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Role of telomerase in cell senescence and oncogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomerase and DNA end replication: no longer a lagging strand problem?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomeres shorten during ageing of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Human endothelial cell life extension by telomerase expression

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A survey of telomerase activity in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Senescence Induced by Altered Telomere State, Not Telomere Loss

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A telomere-independent senescence mechanism is the sole barrier to Syrian hamster cell immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Beyond the Nucleosome: Epigenetic Aspects of Position–Effect Variegation in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomere position effect in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Reexpression of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Mutagenic deamination of cytosine residues in DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Determinants of CpG islands: expression in early embryo and isochore structure

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methylation directs a time-dependent repression of transcription initiation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Amounts, synthesis, and some properties of intracisternal A particle-related RNA in early mouse embryos

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methylation, chromatin inheritance, and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

MOLECULAR BIOLOGY:DNA Methylation de Novo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Tandem B1 elements located in a mouse methylation center provide a target for de novo DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

SINE retroposons can be used in vivo as nucleation centers for de novo methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The DNA methyltransferases of mammals

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methylation and chromatin modification.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Cytosine methylation and the ecology of intragenomic parasites

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Bisulfite genomic sequencing: systematic investigation of critical experimental parameters

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA hypomethylation leads to elevated mutation rates

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Growing Y-junction carbon nanotubes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Aging, DNA methylation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The role of DNA methylation in cancer genetic and epigenetics

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methylation represses transcription in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Epigenetic control of gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The role of DNA methyltransferase 1 in growth control

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methylation is a reversible biological signal

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

How does DNA methyltransferase cause oncogenic transformation?

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Regulation of DNA methylation by the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Concurrent replication and methylation at mammalian origins of replication

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Inhibition of DNA methyltransferase inhibits DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methyltransferase inhibition induces the transcription of the tumor suppressor p21(WAF1/CIP1/sdi1).

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Histone deacetylase inhibitor activates the p21/WAF1/Cip1 gene promoter through the Sp1 sites

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The essentials of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Expression of DNA methyl-transferase (DMT) and the cell cycle in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Histone acetylation and the cell-cycle in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2802%2900079-1

7 January 2021

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

1 reference

15 December 2024

https://opencitations.net/index/api/v1/citations/10.1002/J.1460-2075.1992.TB05245.X

Identifiers

DOI

10.1016/S1357-2725(02)00079-1

1 reference

4 August 2017

1 reference