(Q57198273)

5

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Klaus Rajewsky

5

object named as

K Rajewsky

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author name string

Linda Bross

1

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Yosho Fukita

2

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Fraser McBlane

3

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Corinne Démollière

4

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L Bross

1

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Y Fukita

2

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F McBlane

3

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C Démollière

4

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H Jacobs

Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.

6

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language of work or name

English

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publication date

November 2000

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published in

Immunity

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volume

13

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issue

5

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page(s)

589-597

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589-97

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cites work

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7 January 2021

Maturation of the immune response in germinal centers

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7 January 2021

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

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7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

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7 January 2021

Splinkerettes--improved vectorettes for greater efficiency in PCR walking.

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Targeting and subsequent selection of somatic hypermutations in the human V kappa repertoire

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7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription

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7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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7 January 2021

Intraclonal generation of antibody mutants in germinal centres

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7 January 2021

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

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7 January 2021

Simplified mammalian DNA isolation procedure

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7 January 2021

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

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7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

1 reference

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7 January 2021

A novel cytidine deaminase affects antibody diversity

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7 January 2021

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7 January 2021

Somatic hypermutation: how many mechanisms diversify V region sequences?

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7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

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7 January 2021

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin

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7 January 2021

Both DNA strands of antibody genes are hypermutation targets

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7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

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7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

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7 January 2021

Somatic hypermutation

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7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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7 January 2021

Clonal selection and learning in the antibody system

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7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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7 January 2021

Introduction: what mechanism(s) drive hypermutation?

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7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

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7 January 2021

Somatic hypermutation in 5' flanking regions of heavy chain antibody variable regions

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7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

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7 January 2021

Natural occurrence and origin of somatically mutated memory B cells in mice

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7 January 2021

The role of clonal selection and somatic mutation in autoimmunity

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7 January 2021

Progress in understanding the mechanism and consequences of somatic hypermutation

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7 January 2021

Somatic generation of antibody diversity

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7 January 2021

The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response

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7 January 2021

Somatic hypermutation, transcription, and DNA mismatch repair

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7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

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7 January 2021