(Q24682616)

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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

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Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease (English)

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heavy chain disease

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inferred from title

object named as

R Küppers

3

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author name string

T Goossens

1

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U Klein

2

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language of work or name

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publication date

3 March 1998

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Proceedings of the National Academy of Sciences of the United States of America

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95

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5

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2463-8

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Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

7 April 2017

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

7 April 2017

https://api.crossref.org/works/10.1073%2FPNAS.95.5.2463

7 January 2021

based on heuristic

inferred from DOI database lookup

Somatic generation of antibody diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

7 April 2017

Hodgkin and Reed-Sternberg cells in lymphocyte predominant Hodgkin disease represent clonal populations of germinal center-derived tumor B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

BCL8, a novel gene involved in translocations affecting band 15q11-13 in diffuse large-cell lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Modifying the sequence of an immunoglobulin V-gene alters the resulting pattern of hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Clonal selection and learning in the antibody system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Multistep evolution of B-cell-derived tumors in humans and rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Analysis of somatic mutation in five B cell subsets of human tonsil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Analysis of immunoglobulin gene rearrangements in single B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Gamma heavy chain disease in man. Genomic sequence reveals two noncontiguous deletions in a single gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

The t(8;14) chromosome translocation of the Burkitt lymphoma cell line Daudi occurred during immunoglobulin gene rearrangement and involved the heavy chain diversity region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Generation of a variant t(2;8) translocation of Burkitt's lymphoma by site-specific recombination via the kappa light-chain joining signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V-D-J joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

A DNA insertion/deletion necessitates an aberrant RNA splice accounting for a mu heavy chain disease protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Different regions of the immunoglobulin heavy-chain locus are involved in chromosomal translocations in distinct pathogenetic forms of Burkitt lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

The role of the bcl-2 gene in lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

The pathogenesis of Burkitt's lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Structurally abnormal immunoglobulins in human immunoproliferative disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 September 2017

Molecular single cell studies of normal and transformed lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Diffuse large cell lymphomas are derived from mature B cells carrying V region genes with a high load of somatic mutation and evidence of selection for antibody expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enh

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Burkitt's lymphomas express VH genes with a moderate number of antigen-selected somatic mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Genetic recombination in a chromosomal translocation t(2;8)(p11;q24) of a Burkitt's lymphoma cell line, KOBK101.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

30 May 2018

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.5.2463

21 January 2018

IMGT, the international ImMunoGeneTics database

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.5.2463

21 January 2018

Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 November 2018

Di- and trinucleotide target preferences of somatic mutagenesis in normal and autoreactive B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 November 2018

Detection of the chromosomal translocation t(11;14) by polymerase chain reaction in mantle cell lymphomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 November 2018

Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19376

28 November 2018

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reexpression of RAG-1 and RAG-2 genes in activated mature mouse B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neoteny in lymphocytes: Rag1 and Rag2 expression in germinal center B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

V(D)J Recombinase Activity in a Subset of Germinal Center B Lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic alterations in a case of alpha heavy chain disease leading to the generation of composite exons from the JH region

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482908

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.95.5.2463

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1998PNAS...95.2463G

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release_35skzxevtfbmbcrqlvvt3cx2da

1 reference

https://api.fatcat.wiki/v0/release/35skzxevtfbmbcrqlvvt3cx2da

24 November 2022

based on heuristic

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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