(Q46974186)

English

Neuronal cell death caused by inhibition of intracellular cholesterol trafficking is caspase dependent and associated with activation of the mitochondrial apoptosis pathway

scientific article published on 3 March 2006

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

Neuronal cell death caused by inhibition of intracellular cholesterol trafficking is caspase dependent and associated with activation of the mitochondrial apoptosis pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

author name string

Zhili Huang

1

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

Qingsong Hou

2

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

Nam Sang Cheung

3

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

Qiu-Tian Li

4

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

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publication date

3 March 2006

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

number of pages

12

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Journal of Neurochemistry

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

97

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Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

1

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

280-291

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

Apoptosomes: engines for caspase activation

1 reference

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Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli

1 reference

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21 January 2018

Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

1 reference

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21 January 2018

The Apaf-1 apoptosome: a large caspase-activating complex

1 reference

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21 January 2018

Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms

1 reference

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21 January 2018

Micromolar L-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurones.

1 reference

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Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons

1 reference

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Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

1 reference

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Role of AIF in caspase-dependent and caspase-independent cell death

1 reference

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Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

1 reference

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

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Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

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Apoptosis in Huntington's disease.

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Calcineurin/NFAT-induced up-regulation of the Fas ligand/Fas death pathway is involved in methamphetamine-induced neuronal apoptosis

1 reference

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21 January 2018

Cholesterol accumulates in cell bodies, but is decreased in distal axons, of Niemann-Pick C1-deficient neurons

1 reference

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21 January 2018

Trafficking of cholesterol from cell bodies to distal axons in Niemann Pick C1-deficient neurons

1 reference

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21 January 2018

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

1 reference

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Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos

1 reference

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Mitochondrial control of cell death

1 reference

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21 January 2018

Bcl-2-family proteins and the role of mitochondria in apoptosis

1 reference

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21 January 2018

Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles

1 reference

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21 January 2018

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1 reference

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21 January 2018

Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

1 reference

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21 January 2018

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

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21 January 2018

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

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21 January 2018

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

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21 January 2018

Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders

1 reference

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21 January 2018

Lipid and cholesterol trafficking in NPC.

1 reference

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21 January 2018

Mitochondria: releasing power for life and unleashing the machineries of death

1 reference

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21 January 2018

Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space

1 reference

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21 January 2018

Mitochondrial mechanisms of neural cell apoptosis

1 reference

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21 January 2018

Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

1 reference

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21 January 2018

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

1 reference

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21 January 2018

Toxic proteins released from mitochondria in cell death

1 reference

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21 January 2018

Molecular characterization of mitochondrial apoptosis-inducing factor

1 reference

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21 January 2018

Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome

1 reference

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Apoptosis in Parkinson's disease: signals for neuronal degradation

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Mitochondrial Release of Pro-apoptotic Proteins

1 reference

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

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Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.

1 reference

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Apoptosis accompanied by up-regulation of TNF-alpha death pathway genes in the brain of Niemann-Pick type C disease

1 reference

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21 January 2018

Altered cholesterol metabolism in Niemann-Pick type C1 mouse brains affects mitochondrial function

1 reference

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Apoptosis in the nervous system

1 reference

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21 January 2018

Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release

1 reference

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

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21 January 2018

Identifiers

10.1111/J.1471-4159.2006.03733.X

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 December 2017

http://europepmc.org/abstract/MED/16515545

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