(Q34859478)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

review article

1 reference

title

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

0 references

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Peter Vandenabeele

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

2

Saelens X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

author name string

van Loo G

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

van Gurp M

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

MacFarlane M

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

publication date

1 October 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

13 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

issue

10

1 reference

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13 November 2019

page(s)

1031-1042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12232790%20AND%20SRC:MED&resulttype=core&format=json

Biochemical pathways of caspase activation during apoptosis

13 November 2019

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The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

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HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

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The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

21 January 2018

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The pro-apoptotic Bcl-2 family member tBid localizes to mitochondrial contact sites

21 January 2018

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

21 January 2018

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Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

21 January 2018

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Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

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21 January 2018

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Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

21 January 2018

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Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion

21 January 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

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Mouse models of cell death

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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21 January 2018

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21 January 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast

21 January 2018

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Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.

21 January 2018

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Lipids, cardiolipin and apoptosis: a greasy licence to kill

21 January 2018

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Injected cytochrome c induces apoptosis

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

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The proteolytic procaspase activation network: an in vitro analysis

21 January 2018

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

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Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation.

21 January 2018

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The Apaf-1 apoptosome: a large caspase-activating complex

21 January 2018

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The ancient regulatory-protein family of WD-repeat proteins

21 January 2018

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Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

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Regulation of apoptotic protease activating factor-1 oligomerization and apoptosis by the WD-40 repeat region

21 January 2018

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A mutational epitope for cytochrome C binding to the apoptosis protease activation factor-1

21 January 2018

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Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

21 January 2018

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Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

21 January 2018

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

21 January 2018

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Apaf1 is required for mitochondrial pathways of apoptosis and brain development

21 January 2018

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Differential requirement for caspase 9 in apoptotic pathways in vivo.

21 January 2018

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Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

21 January 2018

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Two distinct pathways leading to nuclear apoptosis

21 January 2018

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NADH oxidase activity of mitochondrial apoptosis-inducing factor

21 January 2018

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Heat-shock protein 70 antagonizes apoptosis-inducing factor

21 January 2018

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Signals for death and survival: A two-step mechanism for cavitation in the vertebrate embryo

21 January 2018

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Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

21 January 2018

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Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

21 January 2018

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 January 2018

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Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

21 January 2018

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Structural basis of IAP recognition by Smac/DIABLO

21 January 2018

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Structural basis of caspase-7 inhibition by XIAP

21 January 2018

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Structural basis for the inhibition of caspase-3 by XIAP

21 January 2018

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Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides

21 January 2018

1 reference

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Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM.

21 January 2018

1 reference

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The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

21 January 2018

1 reference

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Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

21 January 2018

1 reference

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sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein

21 January 2018

1 reference

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Drosophila sickle is a novel grim-reaper cell death activator

21 January 2018

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The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, grim, and hid.

21 January 2018

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The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

21 January 2018

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Generation and characterization of Smac/DIABLO-deficient mice.

21 January 2018

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Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

21 January 2018

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Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

21 January 2018

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Expression, purification, and functional analysis of the human serine protease HtrA2

21 January 2018

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Protein-protein interactions: PDZ domain networks

21 January 2018

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Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

21 January 2018

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Protein modules as organizers of membrane structure

21 January 2018

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CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B

21 January 2018

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Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein

21 January 2018

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Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

21 January 2018

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The HtrA family of serine proteases

21 January 2018

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A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

21 January 2018

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Mitochondrial endonuclease G is important for apoptosis in C. elegans.

21 January 2018

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Primers for mitochondrial DNA replication generated by endonuclease G.

21 January 2018

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Review: nuclear events in apoptosis

21 January 2018

1 reference

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

1 reference

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Baculoviruses and apoptosis: the good, the bad, and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

21 January 2018

Viruses and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Programmed cell death, mitochondria and the plant hypersensitive response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Detection of pro-caspase-3 in cytosol and mitochondria of various tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Mitochondrial release of caspase-2 and -9 during the apoptotic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Caspases: their intracellular localization and translocation during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Pre-processed caspase-9 contained in mitochondria participates in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2

21 January 2018

1 reference

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1H-n.m.r. evaluation of the ferricytochrome c-cardiolipin interaction. Effect of superoxide radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

S-nitrosylation regulates apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

S-Nitrosylation of mitochondrial caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

The biochemistry of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Cardiolipin provides specificity for targeting of tBid to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Expression and functional analysis of Apaf-1 isoforms. Extra Wd-40 repeat is required for cytochrome c binding and regulated activation of procaspase-9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021

Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401088

7 January 2021