(Q36575386)

15 August 2017

1 reference

title

Enhancing and confirming the specificity of RNAi experiments (English)

1 reference

15 August 2017

Bryan R Cullen

1

1 reference

15 August 2017

publication date

1 September 2006

1 reference

15 August 2017

1 reference

15 August 2017

volume

3

1 reference

15 August 2017

issue

9

1 reference

15 August 2017

page(s)

677-681

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

15 August 2017

cites work

1 reference

Transcription and processing of human microRNA precursors

21 January 2018

1 reference

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

1 reference

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

21 January 2018

1 reference

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

1 reference

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

21 January 2018

1 reference

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

21 January 2018

1 reference

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors

21 January 2018

1 reference

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

1 reference

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

21 January 2018

1 reference

Interactions between double-stranded RNA regulators and the protein kinase DAI

21 January 2018

1 reference

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

21 January 2018

1 reference

Specificity of short interfering RNA determined through gene expression signatures

21 January 2018

1 reference

Induction of the interferon response by siRNA is cell type- and duplex length-dependent

21 January 2018

1 reference

Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs

21 January 2018

1 reference

On the art of identifying effective and specific siRNAs

21 January 2018

1 reference

Induction of stable RNA interference in mammalian cells

21 January 2018

1 reference

Identification of novel genes coding for small expressed RNAs

21 January 2018

1 reference

A mechanism by which adenovirus virus-associated RNAI controls translation in a transient expression assay

21 January 2018

1 reference

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

21 January 2018

1 reference

Off-target effects by siRNA can induce toxic phenotype

21 January 2018

1 reference

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

1 reference

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

21 January 2018

1 reference

RNA interference in human cells is restricted to the cytoplasm

21 January 2018

1 reference

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NMETH913

1 reference

15 August 2017

1 reference