(Q36272950)

13 August 2017

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title

Induction of stable RNA interference in mammalian cells (English)

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13 August 2017

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Bryan R Cullen

1

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13 August 2017

publication date

1 March 2006

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13 August 2017

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13 August 2017

volume

13

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13 August 2017

issue

6

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13 August 2017

page(s)

503-508

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Perspective: machines for RNAi

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

siRNAs can function as miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Identification of novel genes coding for small expressed RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Processing of primary microRNAs by the Microprocessor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Interactions between double-stranded RNA regulators and the protein kinase DAI

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Rational siRNA design for RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Local RNA target structure influences siRNA efficacy: a systematic global analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

A statistical sampling algorithm for RNA secondary structure prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Sfold web server for statistical folding and rational design of nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

RNA interference in human cells is restricted to the cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Specific and potent RNAi in the nucleus of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Retroviral delivery of small interfering RNA into primary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Inhibition of human immunodeficiency virus type 1 replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

Target accessibility dictates the potency of human RISC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

inferred from DOI database lookup

7 January 2021

based on heuristic

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302656

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302656

1 reference

13 August 2017

1 reference