(Q35632517)

English

The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization

scientific article published on 26 January 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitization (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

metastatic melanoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

4

object named as

Mario Sznol

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Harriet M Kluger

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Mary M McCarthy

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Ayesha B Alvero

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Stephan Ariyan

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Robert L Camp

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

David L Rimm

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Gil Mor

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

26 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Journal of Translational Medicine

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Europe PubMed Central

PubMed publication ID

9 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

copyright license

Creative Commons Attribution 2.0 Generic

26 January 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Phenoxodiol, a novel approach for the treatment of ovarian cancer

1 reference

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Expression of tumor necrosis factor--related apoptosis-inducing ligand receptors 1 and 2 in melanoma

1 reference

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Cancer statistics, 2006

1 reference

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12 July 2018

Molecular mechanism of phenoxodiol-induced apoptosis in ovarian carcinoma cells

1 reference

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12 July 2018

Chemotherapy for metastatic melanoma

1 reference

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Targeting XIAP for the treatment of malignancy

1 reference

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Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction

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Targeting the IAP family of caspase inhibitors as an emerging therapeutic strategy.

1 reference

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

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ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

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Increased expression of apoptosis inhibitor protein XIAP contributes to anoikis resistance of circulating human prostate cancer metastasis precursor cells.

1 reference

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Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells.

1 reference

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12 July 2018

Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells

1 reference

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Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.

1 reference

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12 July 2018

Resistance of ovarian carcinoma cells to docetaxel is XIAP dependent and reversible by phenoxodiol.

1 reference

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Apoptosis, Bcl-2 antisense, and cancer therapy

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The role of taxanes in the treatment of metastatic melanoma

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Management of cutaneous melanoma

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12 July 2018

XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer

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DNA repair pathways in drug resistance in melanoma

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12 July 2018

Exposure of melanoma cells to dacarbazine results in enhanced tumor growth and metastasis in vivo

1 reference

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12 July 2018

V599EB-RAF is an oncogene in melanocytes

1 reference

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Quantitative determination of expression of the prostate cancer protein alpha-methylacyl-CoA racemase using automated quantitative analysis (AQUA): a novel paradigm for automated and continuous biomarker measurements

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cDNA microarray analysis of invasive and tumorigenic phenotypes in a breast cancer model

1 reference

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12 July 2018

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1796544

12 July 2018

Death receptors and melanoma resistance to apoptosis

1 reference

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Apoptosis and melanoma chemoresistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1796544

12 July 2018

Phenoxodiol – an isoflavone analog – induces apoptosis in chemoresistant ovarian cancer cells

1 reference

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Maternal serum of women with pre-eclampsia reduces trophoblast cell viability: evidence for an increased sensitivity to Fas-mediated apoptosis

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Apoptosis regulators and responses in human melanocytic and keratinocytic cells

1 reference

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Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer

1 reference

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Apoptosis and chemoresistance in transgenic cancer models

1 reference

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IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition

1 reference

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Apoptosis is critical for drug response in vivo

1 reference

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Characterization of XIAP-deficient mice

1 reference

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Down-regulation of X-linked inhibitor of apoptosis protein induces apoptosis in chemoresistant human ovarian cancer cells

1 reference

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The biochemistry of apoptosis

1 reference

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Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

1 reference

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

1 reference

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Malignant melanoma: incidence issues and their effect on diagnosis and treatment in the 1990s

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Phase II trial of carboplatin in patients with advanced melanoma

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1796544

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XIAP expression is an independent prognostic marker in clear-cell renal carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1796544

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Her2/neu is not a commonly expressed therapeutic target in melanoma -- a large cohort tissue microarray study

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Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis

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The tyrphostin AG1024 accelerates the degradation of phosphorylated forms of retinoblastoma protein (pRb) and restores pRb tumor suppressive function in melanoma cells

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Cisplatin hydration with and without mannitol diuresis in refractory disseminated malignant melanoma: a southwest oncology group study

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https://pubmed.ncbi.nlm.nih.gov/17257402

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based on heuristic

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Phase II trial of carboplatin in patients with metastatic malignant melanoma. A report from the Eastern Cooperative Oncology Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/17257402

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based on heuristic

inferred from PubMed ID database lookup

Automated quantitative analysis of HDM2 expression in malignant melanoma shows association with early-stage disease and improved outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17257402

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based on heuristic

inferred from PubMed ID database lookup

Phase I trial of phenoxodiol delivered by continuous intravenous infusion in patients with solid cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17257402

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based on heuristic

inferred from PubMed ID database lookup

Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma

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https://pubmed.ncbi.nlm.nih.gov/17257402

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1479-5876-5-6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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