(Q33991803)

30 July 2017

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title

Targeting XIAP for the treatment of malignancy (English)

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30 July 2017

A D Schimmer

1

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30 July 2017

S Dalili

series ordinal

2

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30 July 2017

R A Batey

series ordinal

3

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30 July 2017

S J Riedl

series ordinal

4

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30 July 2017

publication date

1 February 2006

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Cell Death & Differentiation

30 July 2017

published in

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30 July 2017

volume

13

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30 July 2017

issue

2

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30 July 2017

page(s)

179-188

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Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice

30 July 2017

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7 January 2021

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics

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7 January 2021

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7 January 2021

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7 January 2021

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Caspase-independent cell death in AML: caspase inhibition in vitro with pan-caspase inhibitors or in vivo by XIAP or Survivin does not affect cell survival or prognosis

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP.

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7 January 2021

Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer

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7 January 2021

Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.

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7 January 2021

Structure-based design of potent, conformationally constrained Smac mimetics

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401826

7 January 2021

Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics.

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7 January 2021

Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database

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7 January 2021

Antitumor, anti-inflammatory and analgesic property of embelin, a plant product

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7 January 2021

Reversible contraception like activity of embelin in male dogs (Canis indicus Linn)

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7 January 2021

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

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7 January 2021

A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

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7 January 2021

Development and characterization of nonpeptidic small molecule inhibitors of the XIAP/caspase-3 interaction

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7 January 2021

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

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7 January 2021

Cellular, biochemical, and genetic analysis of mechanism of small molecule IAP inhibitors

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401826

7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

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7 January 2021

ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: a study by the GIMEMA Working Party o

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7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401826

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30 July 2017

1 reference