(Q34554757)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

review article

1 reference

title

Rho GTPases in transformation and metastasis (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

author name string

Alan Hall

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

publication date

1 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

Advances in Cancer Research

8 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

volume

84

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

page(s)

57-80

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

8 December 2019

cites work

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7 January 2021

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

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7 January 2021

Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1.

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7 January 2021

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

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7 January 2021

Chp, a homologue of the GTPase Cdc42Hs, activates the JNK pathway and is implicated in reorganizing the actin cytoskeleton

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7 January 2021

Motility and invasion are differentially modulated by Rho family GTPases

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7 January 2021

Induction of membrane ruffling and fluid-phase pinocytosis in quiescent fibroblasts by ras proteins

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7 January 2021

Rho GTPases and their effector proteins

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7 January 2021

Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration

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7 January 2021

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

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7 January 2021

Coding sequence of human rho cDNAs clone 6 and clone 9

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7 January 2021

Genomic analysis of metastasis reveals an essential role for RhoC

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7 January 2021

Rho proteins induce metastatic properties in vivo

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7 January 2021

Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

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7 January 2021

Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

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7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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7 January 2021

The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements

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7 January 2021

Tiam1 mutations in human renal-cell carcinomas

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7 January 2021

Rho-like GTPases in tumor cell invasion

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7 January 2021

Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

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7 January 2021

Rho GTPases are over-expressed in human tumors.

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7 January 2021

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

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7 January 2021

Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Characterization of RAC3, a novel member of the Rho family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Rho GTPases and the Actin Cytoskeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The Hallmarks of Cancer

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

New CD44 splice variants associated with human breast cancers

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

An essential part for Rho-associated kinase in the transcellular invasion of tumor cells.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

A Rac1 effector site controlling mitogenesis through superoxide production

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Overexpression of RhoA mRNA is associated with advanced stage in testicular germ cell tumour

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The insert region of Rac1 is essential for membrane ruffling but not cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

1 reference

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7 January 2021

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7 January 2021

Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation

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7 January 2021

Initial sequencing and analysis of the human genome

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

A novel Cdc42Hs mutant induces cellular transformation

1 reference

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7 January 2021

Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

1 reference

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7 January 2021

A role for Rac in Tiam1-induced membrane ruffling and invasion

1 reference

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7 January 2021

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Oncogene ect2 is related to regulators of small GTP-binding proteins

1 reference

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7 January 2021

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

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7 January 2021

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Nonrandom 4p13 rearrangements of the RhoH/TTF gene, encoding a GTP-binding protein, in non-Hodgkin's lymphoma and multiple myeloma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Transformation mediated by RhoA requires activity of ROCK kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Cross-talk between Ras and Rho signalling pathways in transformation favours proliferation and increased motility

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1 reference

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7 January 2021

Isolation of a novel human cDNA (rhoHP1) homologous to rho genes

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7 January 2021

PTEN: life as a tumor suppressor

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7 January 2021

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Rho GTPases and signaling networks

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

5q-, twenty-five years later: a synopsis

1 reference

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7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Growth-regulated expression of rhoG, a new member of the ras homolog gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

CDC42 and FGD1 cause distinct signaling and transforming activities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Dependence of Dbl and Dbs transformation on MEK and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The gamma-subunit of the coatomer complex binds Cdc42 to mediate transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Transformation activity of Cdc42 requires a region unique to Rho-related proteins

1 reference

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7 January 2021

Nucleotide sequence of human rho cDNA clone 12.

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https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Small GTP-binding protein Rho stimulates the actomyosin system, leading to invasion of tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

G2A is an oncogenic G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Mas Oncogene Signaling and Transformation Require the Small GTP-Binding Protein Rac

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

Loop 6 of RhoA confers specificity for effector binding, stress fiber formation, and cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-230X%2802%2984003-9

7 January 2021

10.1016/S0065-230X(02)84003-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11883532%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference