(Q28646215)

3 February 2017

1 reference

Europe PubMed Central

title

Rho GTPases and signaling networks (English)

1 reference

3 February 2017

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9308960

17 November 2024

signal transduction

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9308960

17 November 2024

author name string

L. Van Aelst

1

1 reference

3 February 2017

C. D'Souza-Schorey

2

1 reference

3 February 2017

language of work or name

1 reference

15 September 1997

1 reference

3 February 2017

1 reference

3 February 2017

volume

11

1 reference

3 February 2017

issue

18

1 reference

3 February 2017

page(s)

2295–2322

1 reference

Characterization, expression and chromosomal localization of a human gene homologous to the mouse Lsc oncogene, with strongest expression in hematopoetic tissues

3 February 2017

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Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

17 November 2024

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Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

17 November 2024

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Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

17 November 2024

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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

17 November 2024

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Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

17 November 2024

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Identification of a mouse p21Cdc42/Rac activated kinase

17 November 2024

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An essential role for a phospholipid transfer protein in yeast Golgi function

17 November 2024

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Myogenesis and muscle patterning in Drosophila.

17 November 2024

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Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in Yeast

17 November 2024

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The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains

17 November 2024

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Signal transduction of phagocytosis

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Proteins regulating Ras and its relatives

17 November 2024

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Regulation of the phagocyte respiratory burst by small GTP-binding proteins

17 November 2024

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Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

17 November 2024

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The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases

17 November 2024

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Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

17 November 2024

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The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

17 November 2024

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

17 November 2024

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Focal adhesions, contractility, and signaling

17 November 2024

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Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

17 November 2024

34

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Effects of profilin and profilactin on actin structure and function in living cells

17 November 2024

35

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The Dbl family of oncogenes

17 November 2024

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Cooperative interaction of S. pombe proteins required for mating and morphogenesis

17 November 2024

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c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

17 November 2024

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GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more

17 November 2024

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Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

17 November 2024

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The LIM domain-containing Dbm1 GTPase-activating protein is required for normal cellular morphogenesis in Saccharomyces cerevisiae

17 November 2024

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https://api.crossref.org/works/10.1101/GAD.11.18.2295

Requirement of CDC42 for Salmonella-induced cytoskeletal and nuclear responses

17 November 2024

45

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https://api.crossref.org/works/10.1101/GAD.11.18.2295

The Caenorhabditis elegans p21-activated kinase (CePAK) colocalizes with CeRac1 and CDC42Ce at hypodermal cell boundaries during embryo elongation

17 November 2024

48

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase.

17 November 2024

49

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

17 November 2024

50

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

17 November 2024

51

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

17 November 2024

52

1 reference

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Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

17 November 2024

54

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

17 November 2024

55

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts.

17 November 2024

56

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis

17 November 2024

57

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https://api.crossref.org/works/10.1101/GAD.11.18.2295

Galpha12 stimulates c-Jun NH2-terminal kinase through the small G proteins Ras and Rac.

17 November 2024

59

1 reference

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chickadee encodes a profilin required for intercellular cytoplasm transport during Drosophila oogenesis

17 November 2024

60

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https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

17 November 2024

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Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway

17 November 2024

62

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

17 November 2024

63

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Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

17 November 2024

64

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

17 November 2024

65

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

17 November 2024

66

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

17 November 2024

67

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Bcr encodes a GTPase-activating protein for p21rac

17 November 2024

68

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

17 November 2024

69

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Inhibition of Rac function using antisense oligonucleotides

17 November 2024

70

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos.

17 November 2024

72

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho1p, a yeast protein at the interface between cell polarization and morphogenesis

17 November 2024

73

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A regulatory role for ARF6 in receptor-mediated endocytosis

17 November 2024

74

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements

17 November 2024

75

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

17 November 2024

77

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila

17 November 2024

78

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP.

17 November 2024

79

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The O-2 Generating NADPH Oxidase of Phagocytes: Structure and Methods of Detection

17 November 2024

80

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

17 November 2024

81

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus

17 November 2024

82

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus

17 November 2024

83

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Isolation of a new human oncogene from a diffuse B-cell lymphoma.

17 November 2024

84

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis

17 November 2024

85

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

17 November 2024

87

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

17 November 2024

88

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Involvement of the epidermal growth factor receptor in the invasion of cultured mammalian cells by Salmonella typhimurium

17 November 2024

90

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

17 November 2024

92

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Activation of ternary complex factor Elk-1 by stress-activated protein kinases

17 November 2024

93

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

17 November 2024

94

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

17 November 2024

95

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Mechanism of the interaction of human platelet profilin with actin

17 November 2024

96

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

17 November 2024

98

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Transcription factor ATF2 regulation by the JNK signal transduction pathway

17 November 2024

99

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

17 November 2024

100

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

ras and GAP--who's controlling whom?

17 November 2024

101

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

17 November 2024

102

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Lck regulates Vav activation of members of the Rho family of GTPases

17 November 2024

103

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

17 November 2024

105

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect.

17 November 2024

106

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function

17 November 2024

107

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Deletion analysis of the lambda tR1 termination region. Effect of sequences near the transcript release sites, and the minimum length of rho-dependent transcripts

17 November 2024

108

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

17 November 2024

109

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs

17 November 2024

110

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

17 November 2024

111

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

17 November 2024

112

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Phosphatidylinositol transfer protein required for ATP-dependent priming of Ca(2+)-activated secretion

17 November 2024

113

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The GTPase Rho has a critical regulatory role in thymus development

17 November 2024

114

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

MAP kinase pathways in yeast: for mating and more

17 November 2024

115

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

17 November 2024

116

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

17 November 2024

117

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

17 November 2024

118

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities

17 November 2024

119

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Tandem SH2 binding sites mediate the RasGAP-RhoGAP interaction: a conformational mechanism for SH3 domain regulation

17 November 2024

121

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae

17 November 2024

122

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

17 November 2024

123

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions

17 November 2024

125

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

17 November 2024

126

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Salmonella typhimurium induces membrane ruffling by a growth factor-receptor-independent mechanism

17 November 2024

127

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase

17 November 2024

128

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

17 November 2024

129

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

17 November 2024

130

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

17 November 2024

132

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

17 November 2024

133

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

17 November 2024

134

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

17 November 2024

135

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

17 November 2024

138

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The GTPase-activating protein n-chimaerin cooperates with Rac1 and Cdc42Hs to induce the formation of lamellipodia and filopodia

17 November 2024

139

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

17 November 2024

140

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Protein kinase cascades activated by stress and inflammatory cytokines

17 November 2024

141

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

17 November 2024

142

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation of receptor-mediated endocytosis by Rho and Rac.

17 November 2024

143

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

17 November 2024

146

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Pheromone response in yeast: association of Bem1p with proteins of the MAP kinase cascade and actin

17 November 2024

147

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins

17 November 2024

148

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes

17 November 2024

151

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

17 November 2024

152

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Bee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton

17 November 2024

153

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.

17 November 2024

154

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A novel Cdc42Hs mutant induces cellular transformation

17 November 2024

156

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes

17 November 2024

157

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways

17 November 2024

158

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion

17 November 2024

159

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.

17 November 2024

160

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho- and Rac-dependent Assembly of Focal Adhesion Complexes and Actin Filaments in Permeabilized Fibroblasts: An Essential Role for Ezrin/Radixin/Moesin Proteins

17 November 2024

161

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A novel partner for the GTP-bound forms of rho and rac

17 November 2024

162

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family

17 November 2024

163

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

17 November 2024

164

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe

17 November 2024

165

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Wortmannin-sensitive Trafficking Pathways in Chinese Hamster Ovary Cells

17 November 2024

170

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho

17 November 2024

171

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Yeast src homology region 3 domain-binding proteins involved in bud formation

17 November 2024

172

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding protein Rho1p is localized on the Golgi apparatus and post-Golgi vesicles in Saccharomyces cerevisiae

17 November 2024

173

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2

17 November 2024

174

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A role for Rac in Tiam1-induced membrane ruffling and invasion

17 November 2024

175

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

17 November 2024

176

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Oncogene ect2 is related to regulators of small GTP-binding proteins

17 November 2024

177

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

17 November 2024

178

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The morphogenesis of cell hairs on Drosophila wings.

17 November 2024

179

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Cell type-specific roles for Cdc42, Rac, and RhoL in Drosophila oogenesis

17 November 2024

180

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Endosome dynamics regulated by a Rho protein.

17 November 2024

181

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

D4-GDI, a substrate of CPP32, is proteolyzed during Fas-induced apoptosis

17 November 2024

182

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

17 November 2024

183

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho effectors and reorganization of actin cytoskeleton

17 November 2024

184

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Opposite effects of cofilin and profilin from porcine brain on rate of exchange of actin-bound adenosine 5'-triphosphate

17 November 2024

185

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells

17 November 2024

186

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

17 November 2024

187

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Activation of the small GTP-binding proteins rho and rac by growth factor receptors.

17 November 2024

188

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae.

17 November 2024

189

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways

17 November 2024

190

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

17 November 2024

191

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

17 November 2024

194

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

17 November 2024

195

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase

17 November 2024

196

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.

17 November 2024

197

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

17 November 2024

199

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

17 November 2024

201

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Drosophila spectrin: the membrane skeleton during embryogenesis

17 November 2024

202

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments.

17 November 2024

204

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP dissociation inhibitors

17 November 2024

205

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

p70 S6 kinase: an enigma with variations

17 November 2024

207

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Phosphorylation of c-jun mediated by MAP kinases.

17 November 2024

208

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase.

17 November 2024

209

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

An essential role for Rac in Ras transformation

17 November 2024

211

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A role for Rho in Ras transformation

17 November 2024

212

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

17 November 2024

213

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

17 November 2024

214

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase

17 November 2024

215

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

17 November 2024

216

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

17 November 2024

217

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

17 November 2024

218

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A novel type of myosin implicated in signalling by rho family GTPases

17 November 2024

219

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.

17 November 2024

220

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rac is required for v-Abl tyrosine kinase to activate mitogenesis

17 November 2024

221

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

17 November 2024

222

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells

17 November 2024

223

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

17 November 2024

224

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

17 November 2024

226

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

17 November 2024

227

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

17 November 2024

229

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

17 November 2024

230

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes

17 November 2024

231

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes

17 November 2024

232

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

TOR2 is required for organization of the actin cytoskeleton in yeast

17 November 2024

233

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2.

17 November 2024

234

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

17 November 2024

235

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The MAPK signaling cascade

17 November 2024

236

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Emerging from the Pak: the p21-activated protein kinase family.

17 November 2024

237

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

17 November 2024

238

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

17 November 2024

239

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes

17 November 2024

240

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

17 November 2024

241

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

17 November 2024

242

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Lamellipodia architecture: actin filament turnover and the lateral flow of actin filaments during motility

17 November 2024

243

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers

17 November 2024

244

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Mutation of RGA1, which encodes a putative GTPase-activating protein for the polarity-establishment protein Cdc42p, activates the pheromone-response pathway in the yeast Saccharomyces cerevisiae.

17 November 2024

245

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

On the crawling of animal cells

17 November 2024

246

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

17 November 2024

247

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The role of RhoA in tissue polarity and Frizzled signalling

17 November 2024

248

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

17 November 2024

249

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Phagocytosis by zippers and triggers

17 November 2024

250

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies

17 November 2024

251

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho family GTPases: the cytoskeleton and beyond

17 November 2024

252

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

17 November 2024

253

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

17 November 2024

254

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho as a regulator of the cytoskeleton.

17 November 2024

255

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Control of nonmuscle myosins by phosphorylation

17 November 2024

256

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

17 November 2024

258

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

17 November 2024

259

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

17 November 2024

260

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

17 November 2024

261

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho Family GTPases Bind to Phosphoinositide Kinases

17 November 2024

262

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Ternary complex factors: growth factor regulated transcriptional activators

17 November 2024

264

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons

17 November 2024

266

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

ERM proteins: head-to-tail regulation of actin-plasma membrane interaction

17 November 2024

267

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

17 November 2024

Ras Partners

269

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Oncogenic activity of Tiam1 and Rac1 in NIH3T3 cells.

17 November 2024

271

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

17 November 2024

Integrins and cancer

272

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

17 November 2024

273

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization

17 November 2024

274

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Increased neutrophil respiratory burst in bcr-null mutants

17 November 2024

275

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

17 November 2024

276

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

17 November 2024

277

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

17 November 2024

278

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

17 November 2024

279

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

17 November 2024

280

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Multiple Ras functions can contribute to mammalian cell transformation

17 November 2024

281

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein

17 November 2024

282

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Role of p38 and JNK mitogen-activated protein kinases in the activation of ternary complex factors

17 November 2024

283

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape

17 November 2024

284

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells

17 November 2024

285

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

17 November 2024

286

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.

17 November 2024

287

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.

17 November 2024

288

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG

17 November 2024

289

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein

17 November 2024

290

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

17 November 2024

291

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

17 November 2024

292

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24.

17 November 2024

293

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae

17 November 2024

295

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

The pleckstrin homology domain mediates transformation by oncogenic dbl through specific intracellular targeting

17 November 2024

296

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Signal transduction and actin filament organization

17 November 2024

297

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295

Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity

17 November 2024

298

1 reference

https://api.crossref.org/works/10.1101/GAD.11.18.2295