Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q33801822)
Watch
English
Cyclin-dependent kinases: inhibition and substrate recognition.
scientific article
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Cyclin-dependent kinases: inhibition and substrate recognition
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author
Martin Noble
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
J A Endicott
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
J A Tucker
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
publication date
1 December 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Current Opinion in Structural Biology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
9
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
738-744
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
Cyclin-dependent kinases: engines, clocks, and microprocessors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Understanding the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of CDKs by phosphorylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma protein and cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of pRB phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of E2F by pRB-family proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of cyclin-dependent kinase 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The crystal structure of cyclin A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of cyclin-dependent kinase activation by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional structure of human cyclin H, a positive regulator of the CDK-activating kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure of cyclin H: common mode of kinase activation and specific features
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The dynamics of cyclin dependent kinase structure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active and inactive protein kinases: structural basis for regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The crystal structure of p13suc1, a p34cdc2-interacting cell cycle control protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the yeast cell-cycle control protein, p13suc1, in a strand-exchanged dimer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Xe-p9, a Xenopus Suc1/Cks protein, is essential for the Cdc2-dependent phosphorylation of the anaphase- promoting complex at mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the cyclin-dependent kinase inhibitor p19Ink4d
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR structural characterization of the CDK inhibitor p19INK4d.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the CDK4/6 inhibitory protein p18INK4c provides insights into ankyrin-like repeat structure/function and tumor-derived p16INK4 mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Backbone dynamics of the CDK inhibitor p19(INK4d) studied by 15N NMR relaxation experiments at two field strengths
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor INK4: determination of the solution structure of p18INK4C and demonstration of the functional significance of loops in p18INK4C and p16INK4A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evolving ideas about cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural principles in cell-cycle control: beyond the CDKs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a substrate-targeting domain in cyclin E necessary for phosphorylation of the retinoblastoma protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of substrate binding site of cyclin-dependent kinase 5
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the cyclin-dependent kinase inhibitory domain of the INK4 family as a model for a synthetic tumour suppressor molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CDK inhibition and cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemical inhibitors of cyclin-dependent kinases: insights into design from X-ray crystallographic studies.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-440X%2899%2900038-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-440X(99)00038-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed publication ID
10607671
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10607671
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10607671%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit