(Q30878855)

27 June 2017

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title

PET and MR imaging of neuroinflammation in hepatic encephalopathy (English)

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27 June 2017

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hepatic encephalopathy

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Yun Yan Su

1

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27 June 2017

Gui Fen Yang

2

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27 June 2017

Guang Ming Lu

3

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27 June 2017

Shawn Wu

4

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27 June 2017

Long Jiang Zhang

5

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27 June 2017

publication date

17 December 2014

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27 June 2017

published in

Metabolic Brain Disease

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27 June 2017

volume

30

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27 June 2017

issue

1

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27 June 2017

page(s)

31-45

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Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [¹⁸F]DPA-714.

27 June 2017

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Rats with minimal hepatic encephalopathy due to portacaval shunt show differential increase of translocator protein (18 kDa) binding in different brain areas, which is not affected by chronic MAP-kinase p38 inhibition.

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21 January 2018

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Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation

21 January 2018

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The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model.

21 January 2018

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The role of microbiota in hepatic encephalopathy

21 January 2018

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[11C]-PK11195 PET: quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease?

21 January 2018

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Liver-brain proinflammatory signalling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema.

21 January 2018

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Radiotracer imaging studies in hepatic encephalopathy: ISHEN practice guidelines

21 January 2018

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Evaluation of early cerebral metabolic, perfusion and microstructural changes in HCV-positive patients: a pilot study

21 January 2018

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Value of perfusion-weighted MR imaging in the assessment of early cerebral alterations in neurologically asymptomatic HIV-1-positive and HCV-positive patients

21 January 2018

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Evidence for neuroinflammation and neuroprotection in HCV infection-associated encephalopathy

21 January 2018

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[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats

21 January 2018

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Hepatic encephalopathy: A central neuroinflammatory disorder?

21 January 2018

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Neuroinflammation in acute liver failure: mechanisms and novel therapeutic targets

21 January 2018

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The liver-brain axis in liver failure: neuroinflammation and encephalopathy

21 January 2018

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In vivo imaging of cerebral "peripheral benzodiazepine binding sites" in patients with hepatic encephalopathy

21 January 2018

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Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

PET imaging of acute and chronic inflammation in living mice.

21 January 2018

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Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: ibuprofen restores its motor activity

21 January 2018

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Magnetic resonance spectroscopy to assess neuroinflammation and neuropathic pain

21 January 2018

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Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Magnetic resonance of the brain in chronic and acute liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Brain magnetic resonance in experimental acute-on-chronic liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Distinct spatiotemporal pattern of CNS lesions revealed by USPIO-enhanced MRI in MOG-induced EAE rats implicates the involvement of spino-olivocerebellar pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Current paradigm of the 18-kDa translocator protein (TSPO) as a molecular target for PET imaging in neuroinflammation and neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Imaging of neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Biological applications of magnetic nanoparticles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Molecular imaging of microglial activation in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Hepatic Encephalopathy: From the Pathogenesis to the New Treatments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

11C-PK11195 PET for the in vivo evaluation of neuroinflammation in the rat brain after cortical spreading depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

The yin and yang of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Repertoire of microglial and macrophage responses after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Imaging neuroinflammation after stroke: current status of cellular and molecular MRI strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Microglial proliferation in the brain of chronic alcoholics with hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Gut microbiota and hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

[11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Microglial migration mediated by ATP-induced ATP release from lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Targeted imaging: an important biomarker for understanding disease progression in the era of personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

The role of the immune system in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Acute-on-chronic liver failure: the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Pregnenolone sulfate restores the glutamate-nitric-oxide-cGMP pathway and extracellular GABA in cerebellum and learning and motor coordination in hyperammonemic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Cerebral microglial activation in patients with hepatitis C: in vivo evidence of neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

The application of nanoparticles in gene therapy and magnetic resonance imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

PEG minocycline-liposomes ameliorate CNS autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Peripheral benzodiazepine receptors in the brain of cirrhosis patients with manifest hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Noninvasive molecular imaging of neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Emerging targets in neuroinflammation-driven chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Magnetic resonance molecular imaging of post-stroke neuroinflammation with a P-selectin targeted iron oxide nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Brain edema and inflammatory activation in bile duct ligated rats with diet-induced hyperammonemia: A model of hepatic encephalopathy in cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Demonstration of interstitial cerebral edema with diffusion tensor MR imaging in type C hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Positron emission tomography imaging of neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Systematic review with meta-analysis: the effects of rifaximin in hepatic encephalopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Value of critical flicker frequency and psychometric hepatic encephalopathy score in diagnosis of low-grade hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Reactive astrocytes overexpress TSPO and are detected by TSPO positron emission tomography imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Inflaming the brain: CRPS a model disease to understand neuroimmune interactions in chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Diffusion MRI shows increased water apparent diffusion coefficient in the brains of cirrhotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Reduced PBR/TSPO expression after minocycline treatment in a rat model of focal cerebral ischemia: a PET study using [(18)F]DPA-714.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Evaluation of a radiolabelled peripheral benzodiazepine receptor ligand in the central nervous system inflammation of experimental autoimmune encephalomyelitis: a possible probe for imaging multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Multifunctional magnetic nanoparticles for targeted imaging and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

[18F]DPA-C5yne, a novel fluorine-18-labelled analogue of DPA-714: radiosynthesis and preliminary evaluation as a radiotracer for imaging neuroinflammation with PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Mechanisms of cognitive alterations in hyperammonemia and hepatic encephalopathy: therapeutical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Imaging and nanomedicine in inflammatory atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Why integrin as a primary target for imaging and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Cerebral effects of ammonia in liver disease: current hypotheses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Neuroinflammation in the living brain of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

The synthesis and in vivo pharmacokinetics of fluorinated arachidonic acid: implications for imaging neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Mechanisms, diagnosis and management of hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Structural and functional abnormalities of default mode network in minimal hepatic encephalopathy: a study combining DTI and fMRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

The gut microbiota and the liver: implications for clinical practice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

PET versus SPECT: strengths, limitations and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Cortical brain metabolism as measured by proton spectroscopy is related to memory performance in patients with amnestic mild cognitive impairment and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Minimal hepatic encephalopathy in children with liver cirrhosis: diffusion-weighted MR imaging and proton MR spectroscopy of the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Could (18) F-DPA-714 PET imaging be interesting to use in the early post-stroke period?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Magnetic resonance methods and applications in pharmaceutical research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

How do immune cells support and shape the brain in health, disease, and aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Pathophysiology of cerebral oedema in acute liver failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

In vivo expression of cyclooxygenase-1 in activated microglia and macrophages during neuroinflammation visualized by PET with 11C-ketoprofen methyl ester.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Long-range Ca2+ waves transmit brain-damage signals to microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Minimal hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Imaging of inflammation in the peripheral and central nervous system by magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Visualization of inflammation using (19) F-magnetic resonance imaging and perfluorocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Neuroinflammation and regulation of glial glutamate uptake in neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Neuroinflammatory imaging biomarkers: relevance to multiple sclerosis and its therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Imaging neuroinflammation in vivo in a neuropathic pain rat model with near-infrared fluorescence and ¹⁹F magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Molecular imaging of microglia/macrophages in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

PET imaging of neuroinflammation in a rat traumatic brain injury model with radiolabeled TSPO ligand DPA-714.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

In vivo imaging of inflammation in the peripheral nervous system by (19)F MRI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Psychometric tests for diagnosing minimal hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Dual contrast magnetic resonance imaging tracking of iron-labeled cells in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Non-invasive visualization of CNS inflammation with nuclear and optical imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Metabolic changes of anterior cingulate cortex in patients with hepatic cirrhosis: A magnetic resonance spectroscopy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Altered brain functional connectivity in patients with cirrhosis and minimal hepatic encephalopathy: a functional MR imaging study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Multimodality MR imaging findings of low-grade brain edema in hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Resting-state functional magnetic resonance imaging in hepatic encephalopathy: current status and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Pathogenesis of hepatic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-014-9633-1

Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain

21 January 2018

1 reference

12 December 2020

Hepatic encephalopathy in chronic liver disease: 2014 Practice Guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver

1 reference

12 December 2020

Imaging of delayed-type hypersensitivity reaction by PET and 18F-galacto-RGD.

1 reference

12 December 2020

Microglia activation in hepatic encephalopathy in rats and humans

1 reference

12 December 2020

Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine

1 reference

12 December 2020

Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy

1 reference

12 December 2020

Intestinal microbiota metabolism of a prebiotic to treat hepatic encephalopathy

1 reference

12 December 2020

Brain cytokine flux in acute liver failure and its relationship with intracranial hypertension

1 reference

12 December 2020

Ammonia and inflammation in the pathogenesis of hepatic encephalopathy: Pandora's box?

1 reference

12 December 2020

10.1007/S11011-014-9633-1

Identifiers

DOI

1 reference

Dimensions Publication ID

27 June 2017

1010644443

0 references

1 reference