(Q42725641)

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Rats with minimal hepatic encephalopathy due to portacaval shunt show differential increase of translocator protein (18 kDa) binding in different brain areas, which is not affected by chronic MAP-kinase p38 inhibition.

scientific article published on 4 December 2013

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Europe PubMed Central

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2 March 2020

Rats with minimal hepatic encephalopathy due to portacaval shunt show differential increase of translocator protein (18 kDa) binding in different brain areas, which is not affected by chronic MAP-kinase p38 inhibition (English)

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2 March 2020

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ChEBI release 2020-05-28

hepatic encephalopathy

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based on heuristic

inferred from title

5

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2 March 2020

1

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2 March 2020

author name string

Jennifer L Dziedzic

2

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2 March 2020

Vicente Hernandez-Rabaza

3

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2 March 2020

Tomas R Guilarte

4

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2 March 2020

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4 December 2013

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2 March 2020

Metabolic Brain Disease

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2 March 2020

29

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2 March 2020

4

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2 March 2020

955-963

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Europe PubMed Central

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2 March 2020

Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Experimental models of hepatic encephalopathy: ISHEN guidelines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Glutamatergic and gabaergic neurotransmission and neuronal circuits in hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

The neurosteroid system: implication in the pathophysiology of hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

In vivo imaging of cerebral "peripheral benzodiazepine binding sites" in patients with hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Characteristics of minimal hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Visualising microglial activation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Hepatic encephalopathy--definition, nomenclature, diagnosis, and quantification: final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Region‐selective glutamine synthetase expression in the rat central nervous system following portocaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Increased expression of the peripheral-type benzodiazepine receptor-isoquinoline carboxamide binding protein mRNA in brain following portacaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

The peripheral benzodiazepine receptor is a sensitive indicator of domoic acid neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Increased densities of peripheral-type benzodiazepine receptors in brain autopsy samples from cirrhotic patients with hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Macrophage and astrocyte populations in relation to [3H]PK 11195 binding in rat cerebral cortex following a local ischaemic lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Increased densities of binding sites for the 'peripheral-type' benzodiazepine receptor ligand [3H]PK 11195 in rat brain following portacaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Different response of astrocytes and bergmann glial cells to portacaval shunt: An immunohistochemical study in the rat cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Glial and nerve cell changes in rats with porto-caval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Glial cell reactions in rats with hyperammoniemia induced by urease or porto-caval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

27 May 2018

Hyperammonemia alters the modulation by different neurosteroids of the glutamate-nitric oxide-cyclic GMP pathway through NMDA- GABAA - or sigma receptors in cerebellum in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

p38 MAP kinase is a therapeutic target for hepatic encephalopathy in rats with portacaval shunts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Hyperammonemia increases GABAergic tone in the cerebellum but decreases it in the rat cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Inflammation and hepatic encephalopathy: ibuprofen restores learning ability in rats with portacaval shunts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Imaging the peripheral benzodiazepine receptor response in central nervous system demyelination and remyelination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Relationship between tumor necrosis factor-alpha and ammonia in patients with hepatic encephalopathy due to chronic liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Down-regulation of astroglial proteins in the rat cerebellum after portacaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Evidence in favour of a role for peripheral-type benzodiazepine receptor ligands in amplification of neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Serum levels of tumor necrosis factor-alpha correlate with severity of hepatic encephalopathy due to chronic liver failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Peripheral benzodiazepine receptor imaging in CNS demyelination: functional implications of anatomical and cellular localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Methamphetamine-induced deficits of brain monoaminergic neuronal markers: distal axotomy or neuronal plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Subclinical hepatic encephalopathy predicts the development of overt hepatic encephalopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Regional and temporal expression of the peripheral benzodiazepine receptor in MPTP neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Tissue-specific alterations of binding sites for peripheral-type benzodiazepine receptor ligand [3H]PK11195 in rats following portacaval anastomosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

The brain in experimental portal-systemic encephalopathy. I. Morphological changes in three animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Heterogeneous astroglial response in the rat spinal cord to long-term portacaval shunt: An immunohistochemical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087148

16 August 2018

Patients with minimal hepatic encephalopathy show impaired mismatch negativity correlating with reduced performance in attention tests

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular and subcellular localization of peripheral benzodiazepine receptors after trimethyltin neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Portacaval shunt in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclinical hepatic encephalopathy impairs daily functioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced expression of peripheral benzodiazepine receptors in trimethyltin-exposed rat brain: a biomarker of neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ammonium chloride on the astrocyte benzodiazepine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The compensatory 'rebound' of reactive astrogliosis: glial fibrillary acidic protein immunohistochemical analysis of reactive astrogliosis after a puncture wound to the brain of rats with portocaval anastomosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translocator protein 18 kDa is involved in the regulation of reactive gliosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 and IL-18 in blood may discriminate cirrhotic patients with and without minimal hepatic encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of ammonia toxicity in mice by PK 11195 and pregnenolone sulfate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphometry of astrocyte and oligodendrocyte ultrastructure after portocaval anastomosis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/24307181

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11011-013-9461-8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307181%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307181%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24307181%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

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