(Q28278642)

Fibroblast growth factor 8

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Anne M Boulet

1

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Anne M Moon

2

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Benjamin R Arenkiel

3

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Mario R Capecchi

Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo

4

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language of work or name

English

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publication date

15 September 2004

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published in

Developmental Biology

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volume

273

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issue

2

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page(s)

361-72

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cites work

1 reference

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Sox9 is required for cartilage formation

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Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations

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Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod

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The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum.

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Roles for FGF8 in the induction, initiation, and maintenance of chick limb development

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A re-examination of proximodistal patterning during vertebrate limb development

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FGF-2: apical ectodermal ridge growth signal for chick limb development

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Limb initiation and development is normal in the absence of the mesonephros

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Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants

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A growth-promoting influence from the mesonephros during limb outgrowth

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Molecular Models for Vertebrate Limb Development

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WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.

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Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud

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Fgf8 signalling from the AER is essential for normal limb development.

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Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development

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The roles of FGFs in the early development of vertebrate limbs

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Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

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Fgf8 is required for outgrowth and patterning of the limbs

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SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

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Pattern formation: old models out on a limb.

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FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

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A positive feedback loop coordinates growth and patterning in the vertebrate limb.

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Distinct transcriptional regulatory mechanisms underlie left-right asymmetric expression of lefty-1 and lefty-2.

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Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

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A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

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Fgf10 is essential for limb and lung formation

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Generalized lacZ expression with the ROSA26 Cre reporter strain

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Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development

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Functions of FGF signalling from the apical ectodermal ridge in limb development

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Patterning Systems—From One End of the Limb to the Other

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Vertebrate limb development--the early stages in chick and mouse

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Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch

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A staging system for mouse limb development

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Parallel expression ofSox9 andCol2a1 in cells undergoing chondrogenesis

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