(Q28139850)

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

2

Peter Ten Dijke

1 reference

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

author name string

K Miyazono

1

0 references

P ten Dijke

2

0 references

C H Heldin

3

0 references

Kohei Miyazono

1

1 reference

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

Carl-Henrik Heldin

3

1 reference

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

language of work or name

English

0 references

publication date

2000

1 reference

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

published in

Advances in Immunology

1 reference

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

volume

75

0 references

page(s)

115-57

0 references

115-157

1 reference

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling

14 April 2017

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Phosphorylated CREB binds specifically to the nuclear protein CBP

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7 January 2021

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes

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7 January 2021

Drosophila dSmad2 and Atr-I transmit activin/TGFbeta signals

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Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

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Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

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7 January 2021

Characterization of functional domains within Smad4/DPC4

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Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3

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7 January 2021

Smad4 (DPC4)--a potent tumour suppressor?

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7 January 2021

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

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7 January 2021

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

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7 January 2021

A kinase subdomain of transforming growth factor-β (TGF-β) type I receptor determines the TGF-β intracellular signaling specificity

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7 January 2021

The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation

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Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

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7 January 2021

Conjunction dysfunction: CBP/p300 in human disease.

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A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals

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7 January 2021

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7 January 2021

The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse

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7 January 2021

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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Interaction and functional cooperation of PEBP2/CBF with Smads. Synergistic induction of the immunoglobulin germline Calpha promoter

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7 January 2021

Transforming growth factor beta activation of p44mapk in proliferating cultures of epithelial cells

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7 January 2021

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

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7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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7 January 2021

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7 January 2021

TGF-β signalling from cell membrane to nucleus through SMAD proteins

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7 January 2021

TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway

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7 January 2021

Dominant-negative Smad2 mutants inhibit activin/Vg1 signaling and disrupt axis formation in Xenopus.

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7 January 2021

Mutations in the SMAD4/DPC4 gene in juvenile polyposis

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7 January 2021

Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes.

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7 January 2021

Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene

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7 January 2021

Crystal structure of the cytoplasmic domain of the type I TGF beta receptor in complex with FKBP12

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7 January 2021

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

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7 January 2021

E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest

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7 January 2021

Smad6 inhibits signalling by the TGF-β superfamily

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7 January 2021

Interplay of signal mediators of decapentaplegic (Dpp): molecular characterization of mothers against dpp, Medea, and daughters against dpp.

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7 January 2021

Smad7 is an activin-inducible inhibitor of activin-induced growth arrest and apoptosis in mouse B cells

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7 January 2021

Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells

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7 January 2021

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

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7 January 2021

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

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7 January 2021

The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation.

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7 January 2021

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

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7 January 2021

Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer

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7 January 2021

Signal transduction by bone morphogenetic proteins

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7 January 2021

Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

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7 January 2021

Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

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7 January 2021

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

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Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer

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7 January 2021

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

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7 January 2021

Opposing BMP and EGF signalling pathways converge on the TGF-β family mediator Smad1

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7 January 2021

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

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7 January 2021

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

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7 January 2021

Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

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7 January 2021

A molecular basis for Smad specificity

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7 January 2021

Roles of pathway-specific and inhibitory Smads in activin receptor signaling

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7 January 2021

Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site

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7 January 2021

Mothers Against Decapentaplegic-Related Protein 2 Expression in Avian Granulosa Cells Is Up-Regulated by Transforming Growth Factor during Ovarian Follicular Development

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7 January 2021

Smad2 overexpression enhances Smad4 gene expression and suppresses CBFA1 gene expression in osteoblastic osteosarcoma ROS17/2.8 cells and primary rat calvaria cells

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7 January 2021

A human Mad protein acting as a BMP-regulated transcriptional activator

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

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7 January 2021

Carboxy-terminally truncated Gli3 proteins associate with Smads

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7 January 2021

FAST-2 is a mammalian winged-helix protein which mediates transforming growth factor beta signals

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7 January 2021

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

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7 January 2021

Assignment of transforming growth factor beta1 and beta3 and a third new ligand to the type I receptor ALK-1

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7 January 2021

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5

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7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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7 January 2021

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

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7 January 2021

TGF-beta signal transduction

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7 January 2021

Identification of two Smad4 proteins in Xenopus. Their common and distinct properties

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7 January 2021

The C-terminal domain of Mad-like signal transducers is sufficient for biological activity in the Xenopus embryo and transcriptional activation

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7 January 2021

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes.

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7 January 2021

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

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7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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7 January 2021

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

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7 January 2021

Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300

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7 January 2021

Smad6 functions as an intracellular antagonist of some TGF-beta family members during Xenopus embryogenesis.

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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7 January 2021

Role of p300, a transcriptional coactivator, in signalling of TGF-beta

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7 January 2021

Smad5 and DPC4 Are Key Molecules in Mediating BMP-2-induced Osteoblastic Differentiation of the Pluripotent Mesenchymal Precursor Cell Line C2C12

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7 January 2021

Smad2 role in mesoderm formation, left-right patterning and craniofacial development

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7 January 2021

TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

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7 January 2021

Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes

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7 January 2021

The DAF-3 Smad protein antagonizes TGF-β-related receptor signaling in the Caenorhabditis elegansdauer pathway

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7 January 2021

The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

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7 January 2021

Physical and functional interaction of SMADs and p300/CBP

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7 January 2021

Mad-related genes in the human

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7 January 2021

Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation

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7 January 2021

ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

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7 January 2021

A role for bone morphogenetic proteins in the induction of cardiac myogenesis

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7 January 2021

TGF-beta-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein

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7 January 2021

A structural basis for mutational inactivation of the tumour suppressor Smad4

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7 January 2021

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

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7 January 2021

Smad1 interacts with homeobox DNA-binding proteins in bone morphogenetic protein signaling

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7 January 2021

Identification of receptors and Smad proteins involved in activin signalling in a human epidermal keratinocyte cell line

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7 January 2021

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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7 January 2021

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

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7 January 2021

Smad4/DPC4 and Smad3 mediate transforming growth factor-beta (TGF-beta) signaling through direct binding to a novel TGF-beta-responsive element in the human plasminogen activator inhibitor-1 promoter

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7 January 2021

Transforming growth factor beta induces IgA production and acts additively with interleukin 5 for IgA production

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7 January 2021

Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling

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7 January 2021

Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor beta-induced smad-dependent transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Histone acetylation and transcriptional regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Somatic alterations of the SMAD-2 gene in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Induction of Smad6 mRNA by bone morphogenetic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Intracellular signaling of osteogenic protein-1 through Smad5 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Characterization of type I receptors for transforming growth factor-beta and activin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Chromatin modification: how to put a HAT on the histones

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Daughters against dpp modulates dpp organizing activity in Drosophila wing development

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

A function of CBP as a transcriptional co-activator during Dpp signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Cloning and characterization of a novel member of the human Mad gene family (MADH6)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

A Smad transcriptional corepressor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

AML and Ets proteins regulate the I alpha1 germ-line promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad1 and Smad5 Act Downstream of Intracellular Signalings of BMP-2 That Inhibits Myogenic Differentiation and Induces Osteoblast Differentiation in C2C12 Myoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Cloning and expression of a rat Smad1: regulation by TGFbeta and modulation by the Ras/MEK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Cross-talk between the Smad1 and Ras/MEK signaling pathways for TGFbeta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad5, a tumor suppressor candidate at 5q31.1, is hemizygously lost and not mutated in the retained allele in human leukemia cell line HL60.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Human Smad3 and Smad4 are sequence-specific transcription activators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Characterization of human FAST-1, a TGF beta and activin signal transducer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Hematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad3 mutant mice develop metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Smad Proteins Physically Interact with Calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

E1A inhibits transforming growth factor-beta signaling through binding to Smad proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

Positive and negative modulation of vitamin D receptor function by transforming growth factor-beta signaling through smad proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2776%2800%2975003-6

7 January 2021

10.1016/S0065-2776(00)75003-6

Identifiers

DOI

2 references

https://doi.org/10.1016%2FS0065-2776%2800%2975003-6

14 April 2017

Consolidated OpenCitations Corpus – April 2017

release_pxiq6mtkmfgnpn6x465jdv54ia

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/pxiq6mtkmfgnpn6x465jdv54ia

24 November 2022

mapped directly with Wikidata item

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

10879283

1 reference

Consolidated OpenCitations Corpus – April 2017