(Q26768501)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1

1 reference

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9 March 2020

Alessandra Marchetti

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Miguel A Del Pozo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

4

Carla Cicchini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

Roberto Moreno-Vicente

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Cecilia Battistelli

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Valeria Noce

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Laura Amicone

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Marco Tripodi

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

language of work or name

English

0 references

publication date

31 January 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

published in

Stem Cells International

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

3543678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

9 March 2020

copyright license

start time

1 January 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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7 April 2017

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Mesenchymal Conversion of Mesothelial Cells Is a Key Event in the Pathophysiology of the Peritoneum during Peritoneal Dialysis

7 April 2017

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Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis

7 April 2017

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Inhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cells

7 April 2017

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TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

7 April 2017

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

7 April 2017

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Smad transcription factors

7 April 2017

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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

7 April 2017

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The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell

7 April 2017

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

7 April 2017

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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

7 April 2017

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TGF-beta-induced epithelial to mesenchymal transition

7 April 2017

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Non-Smad pathways in TGF-beta signaling

7 April 2017

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A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

7 April 2017

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Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

7 April 2017

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p38 MAP-kinases pathway regulation, function and role in human diseases

7 April 2017

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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

7 April 2017

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

7 April 2017

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Inhibition of EGF Receptor Blocks the Development and Progression of Peritoneal Fibrosis

7 April 2017

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A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid

28 September 2017

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miR-9-5p suppresses pro-fibrogenic transformation of fibroblasts and prevents organ fibrosis by targeting NOX4 and TGFBR2

28 September 2017

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The expression profiling and ontology analysis of noncoding RNAs in peritoneal fibrosis induced by peritoneal dialysis fluid

28 September 2017

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IL-6 amplifies TLR mediated cytokine and chemokine production: implications for the pathogenesis of rheumatic inflammatory diseases

28 September 2017

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Astragalus membranaceus inhibits peritoneal fibrosis via monocyte chemoattractant protein (MCP)-1 and the transforming growth factor-β1 (TGF-β1) pathway in rats submitted to peritoneal dialysis

28 September 2017

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A pathogenetic role for endothelin-1 in peritoneal dialysis-associated fibrosis

28 September 2017

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Interleukin-6 signaling drives fibrosis in unresolved inflammation

28 September 2017

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Changes in expression of four molecular marker proteins and one microRNA in mesothelial cells of the peritoneal dialysate effluent fluid of peritoneal dialysis patients

28 September 2017

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Carcinoma-associated fibroblasts derive from mesothelial cells via mesothelial-to-mesenchymal transition in peritoneal metastasis.

28 September 2017

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BMP-7 counteracting TGF-beta1 activities in organ fibrosis

28 September 2017

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Differential expression of long non-coding RNAs in bleomycin-induced lung fibrosis

28 September 2017

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The potential role of HMGB1 release in peritoneal dialysis-related peritonitis

28 September 2017

1 reference

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Cellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis.

28 September 2017

1 reference

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Tgf-beta induced Erk phosphorylation of smad linker region regulates smad signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Relation between microRNA expression in peritoneal dialysis effluent and peritoneal transport characteristics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

miR-31 is a negative regulator of fibrogenesis and pulmonary fibrosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

28 September 2017

MicroRNAs and fibrosis

1 reference

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Pathophysiological changes to the peritoneal membrane during PD-related peritonitis: the role of mesothelial cells.

28 September 2017

1 reference

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The Roles of Mitogen-Activated Protein Kinase Pathways in TGF-β-Induced Epithelial-Mesenchymal Transition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

The p65 subunit of NF-κB and PARP1 assist Snail1 in activating fibronectin transcription

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Blocking TGF-β1 protects the peritoneal membrane from dialysate-induced damage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Human peritoneal mesothelial cells respond to bacterial ligands through a specific subset of Toll-like receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

The pathophysiology of the peritoneal membrane

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Treatment of established peritoneal fibrosis by gene transfer of Smad7 in a rat model of peritoneal dialysis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Cyclooxygenase-2 mediates dialysate-induced alterations of the peritoneal membrane

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Experimental encapsulating peritoneal sclerosis models: pathogenesis and treatment.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

CTGF inhibits BMP-7 signaling in diabetic nephropathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Impact of uremia, diabetes, and peritoneal dialysis itself on the pathogenesis of peritoneal sclerosis: a quantitative study of peritoneal membrane morphology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Molecular basis for the cell type specific induction of SnoN expression by hepatocyte growth factor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

MicroRNAs: a new class of regulatory genes affecting metabolism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Advanced glycation end products and the kidney

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Endotoxin-induced chemokine expression in murine peritoneal mesothelial cells: the role of toll-like receptor 4.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

The myofibroblast in wound healing and fibrocontractive diseases

28 September 2017

1 reference

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Morphological aspects of peritoneal sclerosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

An epistatic mini-circuitry between the transcription factors Snail and HNF4α controls liver stem cell and hepatocyte features exhorting opposite regulation on stemness-inhibiting microRNAs.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

ESRD patients in 2004: global overview of patient numbers, treatment modalities and associated trends.

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

The monocyte chemoattractant protein-1 (MCP-1)/CCR2 system is involved in peritoneal dialysis-related epithelial-mesenchymal transition of peritoneal mesothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Mast cell involvement in the progression of peritoneal fibrosis in rats with chronic renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

IL-17A is a novel player in dialysis-induced peritoneal damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Alterations in proteoglycan components and histopathology of the peritoneum in uraemic and peritoneal dialysis (PD) patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Smad3-dependent and -independent pathways are involved in peritoneal membrane injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Ex vivo reversal of in vivo transdifferentiation in mesothelial cells grown from peritoneal dialysate effluents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Low-GDP peritoneal dialysis fluid ('balance') has less impact in vitro and ex vivo on epithelial-to-mesenchymal transition (EMT) of mesothelial cells than a standard fluid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Gremlin promotes peritoneal membrane injury in an experimental mouse model and is associated with increased solute transport in peritoneal dialysis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Regulation of cyclooxygenase-2 expression in monocytes by ligation of the receptor for advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2016%2F3543678

Transforming growth factor {beta}1 induces epithelial-mesenchymal transition by activating the JNK-Smad3 pathway in rat peritoneal mesothelial cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Evidence for incorporation of free-floating mesothelial cells as a mechanism of serosal healing.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Chronic uremia induces permeability changes, increased nitric oxide synthase expression, and structural modifications in the peritoneum

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Role of mast cell tryptase in renal interstitial fibrosis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Atlas of peritoneal histology.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4752998

Simple peritoneal sclerosis and sclerosing peritonitis: related or distinct entities?

28 November 2018

1 reference

12 December 2020

Altering peritoneal membrane function: removing the GAG?

1 reference

12 December 2020

Association between markers of inflammation, fibrosis and hypervolemia in peritoneal dialysis patients

1 reference

12 December 2020

Twist overexpression promoted epithelial-to-mesenchymal transition of human peritoneal mesothelial cells under high glucose

1 reference

12 December 2020

Effects of epithelial-to-mesenchymal transition on acute stress response in human peritoneal mesothelial cells

1 reference

12 December 2020

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

1 reference

12 December 2020

Induction of hyaluronan metabolism after mechanical injury of human peritoneal mesothelial cells in vitro

1 reference

12 December 2020

Sclerosing peritonitis: a nosological entity

1 reference

12 December 2020

Identifiers

DOI

10.1155/2016/3543678

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

26941801

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26941801%20AND%20SRC:MED&resulttype=core&format=json