(Q28481277)

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Inhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cells

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384029%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Inhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384029%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Raffaele Strippoli

1

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24 January 2020

Maria-Luisa Pérez Lozano

3

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24 January 2020

5

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24 January 2020

Manuel López Cabrera

6

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24 January 2020

Miguel A Del Pozo

7

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24 January 2020

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Ignacio Benedicto

2

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24 January 2020

Teijo Pellinen

4

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Europe PubMed Central

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24 January 2020

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27 February 2012

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24 January 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384029%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

7

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Europe PubMed Central

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24 January 2020

2

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Europe PubMed Central

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24 January 2020

e31492

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Europe PubMed Central

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24 January 2020

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Creative Commons Attribution 4.0 International

27 February 2012

1 reference

April 2022 Public Data File from Crossref

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0 references

Epithelial-mesenchymal transitions in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

The basics of epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Stoichiometry of active smad-transcription factor complexes on DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

TAK1 is an essential regulator of BMP signalling in cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

19 March 2017

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

7 April 2017

TGF-beta and epithelial-to-mesenchymal transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

7 April 2017

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

7 April 2017

TGF-beta-induced epithelial to mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

7 April 2017

Influence of bicarbonate/low-GDP peritoneal dialysis fluid (BicaVera) on in vitro and ex vivo epithelial-to-mesenchymal transition of mesothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Glucocorticoid induces mesenchymal‐to‐epithelial transition and inhibits TGF‐β1‐induced epithelial‐to‐mesenchymal transition and cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

The pathophysiology of the peritoneal membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

The TAK1-TRAF6 signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

HGF and BMP-7 ameliorate high glucose-induced epithelial-to-mesenchymal transition of peritoneal mesothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Cadherin switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

TGF-beta, Smad3 and the process of progressive fibrosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Epithelial to mesenchymal transition and peritoneal membrane failure in peritoneal dialysis patients: pathologic significance and potential therapeutic interventions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Dose-dependent cross-talk between the transforming growth factor-beta and interleukin-1 signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Plasminogen activator inhibitor-1 in chronic kidney disease: evidence and mechanisms of action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Ex vivo analysis of dialysis effluent-derived mesothelial cells as an approach to unveiling the mechanism of peritoneal membrane failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Smad3 as a mediator of the fibrotic response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

PAI-1, fibrosis, and the elusive provisional fibrin matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

Type 1 plasminogen activator inhibitor gene: functional analysis and glucocorticoid regulation of its promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

29 September 2017

c-Jun N-terminal kinase 1 promotes transforming growth factor-β1-induced epithelial-to-mesenchymal transition via control of linker phosphorylation and transcriptional activity of Smad3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

2 June 2018

Peritoneal dialysis and epithelial-to-mesenchymal transition of mesothelial cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Ex vivo reversal of in vivo transdifferentiation in mesothelial cells grown from peritoneal dialysate effluents.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Smad3-dependent and -independent pathways are involved in peritoneal membrane injury

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Human peritoneal mesothelial cells isolated from spent dialysate fluid maintain contaminating macrophages via production of macrophage colony stimulating factor

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0031492

21 January 2018

Expression of the leukocyte early activation antigen CD69 is regulated by the transcription factor AP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288041

27 November 2018

Isolation, culture and characterization of human peritoneal mesothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of the human peritoneal mesothelial cell to injury: an in vitro model of peritoneal wound healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta stimulates the production of extracellular matrix in cultured human peritoneal mesothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paricalcitol attenuates renal interstitial fibrosis in obstructive nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dominant negative TAK1 inhibits cellular fibrotic responses induced by TGF-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22384029

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0031492

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384029%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

2012PLoSO...731492S

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384029%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22384029%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

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