Koç University
Internal Medicine Endocrinology
In the last decade, studies were first done to determine the frequency of G s ␣ and later thyrotropin receptor (TSHR) mutations in benign autonomously functioning thyroid nodules (AFTN). Different frequencies ranging from 0% to 38% for G... more
In this paper, we propose a compliant and tetherless magnetic capsule endoscopic robot. The proposed capsule robot has two key features. First, it has one extra degree of freedom axial contraction capability to perform additional tasks... more
Background: Coronary heart diseases are inversely related to plasma high-density lipoprotein (HDL) level. Paraoxonase-1 (PON1) is mainly associated with HDL and plays a vital role in protection of low-density lipoprotein (LDL) and HDL.... more
Aims/hypothesis: Patients with diabetes mellitus are well known to be at high risk for vascular disease. Circulating endothelial cells (CECs) have been reported to be an ex vivo indicator of vascular injury. We investigated the presence... more
Objective: We hypothesized that many of the pathophysiological mechanisms that cause atherosclerotic disease may be present in early childhood in children with family history of type 2 diabetes. We aimed to investigate the relation of... more
Patients with diabetes have an increased cardiovascular morbidity and mortality despite interventions to prevent these outcomes. Abnormalities in diurnal blood pressure patterns are also associated with excess cardiovascular mortality.... more
Context: Vitamin D receptors are present in many tissues. Hypovitaminosis D is considered to be a risk factor for atherosclerosis. Objective: This study explores the effects of vitamin D replacement on insulin sensitivity, endothelial... more
Effets de la lévothyroxine sur la sensibilité à l'insuline, la fonction endothéliale et les facteurs de risque d'athérosclérose chez les femmes atteintes d'hypothyroïdie
Hiperglisemi hastane yatışı sırasında morbidite ve mortaliteye etki eden önemli bir faktördür [1,2]. Hiperglisemi, hastaların hastanede yatış süresini, yoğun bakıma alınma oranını ve mortaliteyi artırmaktadır [1]. Postoperatif glukoz... more
Advanced glycation endproducts (AGEs) are a group of modified molecules formed by nonenzymatic reactions between the aldehydic group of reducing sugars with nucleic acids , proteins or lipids. Formation and accumulation of AGEs are... more
Autonomously functioning thyroid nodules (AFTNs) can present as hyperfunctioning adenomas or toxic multinodular goiters. In the last decade, a large number of activating mutations have been identified in the thyrotropin receptor (TSHR)... more
Over 7 million people in Turkey have diabetes. Of the 1 million who inject insulin little is known of their habits and injection techniques. We conducted an Injection Technique Questionnaire (ITQ) survey throughout Turkey that involved... more
Turkey has the highest prevalence of diabetes in Europe. It is therefore essential to know the overall cardiovascular risk and reveal the predictors of metabolic control in Turkish adults with diabetes mellitus. A nationwide, multicenter... more
Introduction: Targeting better glycated hemoglobin (HbA1c) and blood pressure (BP) goals may endanger older adults with type 2 diabetes mellitus (T2DM). Overtreatment of T2DM and hypertension is a trending issue, although undertreatment... more
This expert panel of diabetes specialists aimed to provide guidance to healthcare providers on the best practice in the use of innovative continuous glucose monitoring (CGM) techniques through a practical and implementable document that... more
BACKGROUND: Hyperprolactinemia has been reported to be associated with abnormalities of carbohydrate metabolism. The aim of this study was to evaluate the effects of hyperprolactinemia and bromocriptine (Brc) treatment on endothelial... more