Dr. A.K. Karunamoorthi M.Sc., M.Phil., DPHM., Ph.D., FRES (London)
Dr. Kaliyaperumal Karunamoorthi has involved in vigorous teaching and research activities in both national and international settings for more than fifteen years. He has published several book chapters with various eminent publishers in USA, Europe and the rest of the world. He has published copious research articles in various internationally reputed high impact factored peer-reviewed journals.
I have published more than forty research articles in the area of invertebrate zoology in particular entomology, public health in particular medical entomology, pesticide poisoning, vector biology and control in various internationally reputed with high impact factored journals. I have written nearly ten book chapters in relation with public health for the various internationally reputed publishers. I am pleased to inform you that I am currently serving as an Associate Editor in two international peer reviewed journals and an Editorial-Board Member for seven US-based journals.
Current Research Areas:
Socialomics, Social Science Medicine, Health Management, Ethnomedicinal Plants, Traditional Medicinal System, Indian System of Medicine, Medical Entomology, Epidemiology, Biological control of Vectors, Vector Biology, Environmental Health Sciences and Toxicology, Medicinal and Aromatic Plants, Environmental Health Sciences, Ecotoxocology, Wetland Ecology, Clinical Research on HIV/AIDS Prevention, Biochemistry and Bioinformatics. Besides he has remarkable interest with the Ethnopharmacological study of plant-based antimalarial and repellent products and in the study on the impact of climate change on the insect vector of diseases biodiversity, transmission dynamics and epidemiology.
I have published more than forty research articles in the area of invertebrate zoology in particular entomology, public health in particular medical entomology, pesticide poisoning, vector biology and control in various internationally reputed with high impact factored journals. I have written nearly ten book chapters in relation with public health for the various internationally reputed publishers. I am pleased to inform you that I am currently serving as an Associate Editor in two international peer reviewed journals and an Editorial-Board Member for seven US-based journals.
Current Research Areas:
Socialomics, Social Science Medicine, Health Management, Ethnomedicinal Plants, Traditional Medicinal System, Indian System of Medicine, Medical Entomology, Epidemiology, Biological control of Vectors, Vector Biology, Environmental Health Sciences and Toxicology, Medicinal and Aromatic Plants, Environmental Health Sciences, Ecotoxocology, Wetland Ecology, Clinical Research on HIV/AIDS Prevention, Biochemistry and Bioinformatics. Besides he has remarkable interest with the Ethnopharmacological study of plant-based antimalarial and repellent products and in the study on the impact of climate change on the insect vector of diseases biodiversity, transmission dynamics and epidemiology.
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Papers by Dr. A.K. Karunamoorthi M.Sc., M.Phil., DPHM., Ph.D., FRES (London)
In order to pursue an effective research on hemovigilance, a comprehensive search has been conducted by using the premier academic-scientific databases, WHO documents, and English-language search engines. One hundred two appropriate articles were chosen for data extraction, with a particular reference to emerging pathogens transmitted through blood transfusion, specifically malaria. Blood donation screening is done through microscopic examination and immunological assays to improve the safety of blood products by detection major blood-borne pathogens, viz., HIV, HBV, HCV, syphilis, and malarial parasites. Transfusion therapy significantly dwindles the preventable morbidity and mortality attributed to various illnesses and diseases, particularly AIDS, tuberculosis, and malaria. Examination of thick and thin blood smears are performed to detect positivity and to identify the Plasmodium species, respectively. However, all of these existing diagnostic tools have their own limitations in terms of sensitivity, specificity, cost-effectiveness, and lack of resources and skilled personnel. Globally, despite the mandate need of screening blood and its components according to the blood-establishment protocols, it is seldom practiced in the low-income/poverty-stricken settings. In addition, each and every single phase of transfusion chain carries sizable inherent risks from donors to recipients. Interestingly, opportunities also lie ahead to enhance the safety of blood-supply chain and patients. It can be achieved through sustainable blood-management strategies like (1) appropriate usage of precise diagnostic tools/techniques, (2) promoting hemovigilance system, and (3) adopting novel processes of inactivation technology. Furthermore, selection of the zero-risk donors could pave the way to build a transmissible malaria-free world in the near future.
In order to pursue an effective research on hemovigilance, a comprehensive search has been conducted by using the premier academic-scientific databases, WHO documents, and English-language search engines. One hundred two appropriate articles were chosen for data extraction, with a particular reference to emerging pathogens transmitted through blood transfusion, specifically malaria. Blood donation screening is done through microscopic examination and immunological assays to improve the safety of blood products by detection major blood-borne pathogens, viz., HIV, HBV, HCV, syphilis, and malarial parasites. Transfusion therapy significantly dwindles the preventable morbidity and mortality attributed to various illnesses and diseases, particularly AIDS, tuberculosis, and malaria. Examination of thick and thin blood smears are performed to detect positivity and to identify the Plasmodium species, respectively. However, all of these existing diagnostic tools have their own limitations in terms of sensitivity, specificity, cost-effectiveness, and lack of resources and skilled personnel. Globally, despite the mandate need of screening blood and its components according to the blood-establishment protocols, it is seldom practiced in the low-income/poverty-stricken settings. In addition, each and every single phase of transfusion chain carries sizable inherent risks from donors to recipients. Interestingly, opportunities also lie ahead to enhance the safety of blood-supply chain and patients. It can be achieved through sustainable blood-management strategies like (1) appropriate usage of precise diagnostic tools/techniques, (2) promoting hemovigilance system, and (3) adopting novel processes of inactivation technology. Furthermore, selection of the zero-risk donors could pave the way to build a transmissible malaria-free world in the near future.
of malaria were described in numerous ancient medical literatures and treatises worldwide. It
can be fatal, if not promptly diagnosed and treated. In the past, we have eliminated and
eradicated this scourge in several industrialized nations, particularly from much of Europe,
North America, Australia and much of the Middle East by 1970 through vector control
interventions, particularly intra-domiciliary spraying of dichloro-diphenyl-trichloroethane
(DDT) with effective larviciding and public health campaigns. However, early diagnosis,
and prompt and effective treatment with chloroquine have played the pivotal role in the
malaria eradication programme. Recent scientific advancements, discovery of new concepts as
well as bio-molecular tools have significantly enriched our knowledge and understanding
about malarial parasites and mosquito vectors. It has paved the way to formulate several
potent anti-malarials and a prophylactic vaccine. World’s most clinically advanced malaria
vaccine candidate (RTS, S) is now within reach as early as 2015. However, currently the
widespread multi-drug resistant Plasmodium strains is a matter of important concern, as the
parasites have exhibited varied resistance profiles against almost all existing first-line
antimalarials globally. It calls for development of low-cost resistance-proof antimalarials
with new modes of action. In these perspectives this chapter delineates the global burden of
malaria in terms of negative socio-economic, public health and clinical impact, importance of
vector control interventions, and the role of antimalarials in reducing the global malaria