Papers by pratik malusare
Journal of Indian Academy of Oral Medicine and Radiology
Background: Oral leukoplakia is a condition commonly associated with tobacco use. The literature ... more Background: Oral leukoplakia is a condition commonly associated with tobacco use. The literature also has documentation pertaining to likely cancerous transformation of leukoplakia. It is always a challenge to discover a therapeutic modality to prevent this transformation. Imiquimod is an immune response modifier possessing antiviral and anti-tumor activity which is being explored as an off label use in many cancerous conditions. Aim: To show any regression in oral leukoplakia and to test its safety and tolerability. Setting and Design: This is a randomized, open-label, single-centered clinical pilot study carried out with Imiquimod. Material and Methods: Two groups OPD of dental college with topical 5% Imiquimod and Topical Vitamin A (50,000 IU) were compared for their efficacy in the management of oral leukoplakia, pre- and post-treatment clinically and regression of oral dysplasia was observed histopathologically. Unit of improvement was noted for assessing the effectiveness of treatment. Statistical Analysis: Quantitative data were analyzed by Wilcoxon signed test. Results: Topical 5% Imiquimod application resulted in good clinical response +1, +2 unit of improvement with more regression of lesion noted in non-homogeneous leukoplakia and areas with less salivary contamination. Topical Imiquimod 5% is the best alternative to conservative management of moderate to severe dysplasia cases where we can offer more to the patient than just observation, and it is also better than a surgical option where surgery leads to more morbidity, in recurrent cases.
Pyogenic tumor or pregnancy tumor or lobular capillary hemangioma is an inflammatory hyper plasia... more Pyogenic tumor or pregnancy tumor or lobular capillary hemangioma is an inflammatory hyper plasia occurs in oral cavity, due to hormonal effects on blood vessels. It is not a true granuloma or infection, and caused by localised irritation, hormones, trauma seen in between 2nd to 5th decade, more common in pregnant females occurs in gingiva most commonly, then lip, buccal mucosa, tongue, floor of mouth and rarely in hard palate. In this we are going to present a rare case of pyogenic granuloma of hard palate and detailed review in correlation with pregnant females.
Introduction: Oral and pharyngeal cancers are largely preventable and can be successfully treated... more Introduction: Oral and pharyngeal cancers are largely preventable and can be successfully treated when diagnosed at an early stage. Lack of dental practitioner knowledge has been shown to contribute to delays in referral and treatment. Early detection of oral cancers makes them more amenable to treatment, thus reducing morbidity and allowing the greatest chance of cure. The malignancy is often detected at advanced stages, when more aggressive therapies, often with poor and devastating outcomes for the patient, are needed. Aims and objectives: To assess the awareness and knowledge of oral cancer and its early signs and risk factors in dental practitioners. Materials and methods: The data was collected using a self-administered questionnaire related to oral cancer awareness, oral examination habits, delivery of advice on oral cancer risk factors, knowledge of oral cancer risk factors and clinical appearance, preferred point of referral. The questionnaire was given to 100 dental practi...
Aim: The purpose of the study to assess the incidence of retromolar canals and provide informatio... more Aim: The purpose of the study to assess the incidence of retromolar canals and provide information with regard to their course in Indian subpopulation.
Advances in Human Biology, 2021
Aims: The aim of this study is to evaluate the efficacy of supplementary file system in the remov... more Aims: The aim of this study is to evaluate the efficacy of supplementary file system in the removal of gutta-percha and sealer from the root canal system. Subjects and Methods: Forty-five oval single-rooted mandibular premolars were prepared up to size F2 (DENTSPLY ProTaper) and obturated with gutta-percha and sealer and randomly divided into Group I, Group II and Group III (n = 15). Each group was retreated with ProTaper retreatment files and then additionally retreated with Supplementary files, XP EndoFinisher R file, ProTaper F3 and F4 and WaveOne large, respectively. The cone-beam computed tomography scans were taken after obturation, during the first stage retreatment and second stage retreatment to compare the volume of root filling residue that remained after different stages of retreatment. Statistical Analysis Used: ANOVA and Tukey's multiple comparison tests were used to compare the data. Results: Group I exhibited least root canal residue (P < 0.01) as compared to ...
Journal of Evolution of Medical and Dental Sciences, 2019
Acta Scientific Dental Scienecs, 2019
Journal of Indian Academy of Oral Medicine and Radiology, 2019
Objective: The purpose of the study is to explore the capability of the CBCT to provide informati... more Objective: The purpose of the study is to explore the capability of the CBCT to provide information concerning the position and dimensions of the mandibular incisive canal in relation to adjacent anatomical landmarks. Methodology: CBCT scans of 150 subjects were retrospectively studied to analyze the dimensions of the mandibular incisive canal and to assess the relationship of the mandibular incisive canal to the adjacent anatomical structures of the mandible. Results: 150 CBCT scans were evaluated for the position and dimensions of mandibular incisive canal to adjacent structures. In 87% of cases, the MIC was identified and had a mean length of 13.4mm (range, 5.6 to 24.7 mm) on the right side and 12.4 mm (range, 4 to 22.5 mm) on the left side. From the mental foramen, the incisive canal runs forward toward the incisors, in a slight downward direction, with its diameter decreasing as it progresses towards the midline. Discussion: The data from this study indicates surgical anatomic relationships should be considered in pre-surgical planning to avoid neurosensory disturbances and other potential complications. With the increased interest in performing a thorough pre-surgical examination in the inter-foraminal region, crosssectional images should be utilized to obtain information on the appearance, location, and course of the foramina and canals and their relation to other anatomical structures of the jaw.
Dentistry: Advanced Research, 2017
Journal of Oral and Maxillofacial Radiology, 2018
Synovial chondromatosis (SC) of temporomandibular joint (TMJ) is a rare benign disorder in which ... more Synovial chondromatosis (SC) of temporomandibular joint (TMJ) is a rare benign disorder in which mesenchymal remnants of synovial tissue undergo cartilaginous metaplasia. It is usually confined to the superior joint space; however, it can occasionally extend beyond the joint capsule into the cranium, parotid gland, infratemporal fossa, or external auditory meatus. SC of TMJ with intracranial invasion is very rare. Few cases with such large extent of the disease have been reported in the literature. In this report, we present the clinical features and imaging findings of a rare case of TMJ SC perforating the glenoid fossa leading to communication with the base of the skull. This case report attempts to identify clinical characteristics of intracranial extension and highlighting the various imaging modalities which aid in the diagnosis of SC.
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Papers by pratik malusare