In this study, a 35% phosphoric acid gel (3M Scotchbond etchant), a nonrinse etchant (NRC), and t... more In this study, a 35% phosphoric acid gel (3M Scotchbond etchant), a nonrinse etchant (NRC), and two EDTA-containing conditioners (RC-Prep and File-Eze) were tested in vitro for blocking nerve conductance evoked in the rat sciatic nerve after local application. The phosphoric acid gel and NRC completely and irreversibly inhibited conductance. On the other hand, RC-Prep reduced the compound action potentials (cAPs) by 50% in 120 min. With File-Eze, the reduction in cAPs was less than 50% after an application time of 160 min (61.8 ؎ 1.8%). At 160 min the cAPs in the RC-Prep group had been inhibited by 62.4%. These results indicated strong neurotoxic effects of phosphoric acid and NRC when applied directly on exposed pulp in the total etch procedure.
The aim of this study was to compare the cross-sec- tional area of sealer plus voids of Epiphany ... more The aim of this study was to compare the cross-sec- tional area of sealer plus voids of Epiphany sealer surrounding root fillings completed with Resilon cones and laterally compacted gutta-percha. The root canals of extracted human mandibular premolars were pre- pared to a final size of 40 (0.06 taper). The teeth were then randomly assigned into 2 groups (n 12/group)
International Journal of Paediatric Dentistry, 2009
This paper describes the management of self-inflicted trauma by a 4-year-old boy who was mentally... more This paper describes the management of self-inflicted trauma by a 4-year-old boy who was mentally retarded as a result of encephalitis in infancy. There was severe damage to his lower lip, as well as a moderate degree of injury to the skin and nail of his right thumb. Preliminary intervention was made with a mouthguard using silicone elastomeric positioner material, which soon proved ineffective because of poor retention. The problem was overcome successfully through use of a special appliance in which a heat-cured acrylic base was combined with a superstructure made of silicone positioner material retained mechanically with retention loops of 0.7 mm orthodontic wire.
OBJECTIVES: Resin-based dental materials contain various diluent monomers that can interfere with... more OBJECTIVES: Resin-based dental materials contain various diluent monomers that can interfere with vascular function by causing vasorelaxation. In this study, we evaluated the vasoactive potential of hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA), and the possible mechanism(s) of their vascular action on isolated rat aorta. METHODS: Responses of thoracic rat aorta rings were recorded isometrically by using force displacement transducers. After pre-contracting aorta rings, relaxations to HEMA and TEGDMA were recorded in the absence and presence of nitric oxide synthase inhibitor N-nitro-L-arginine methyl ester(L-NAME), cyclooxygenase inhibitor indomethacin, and K+ channel inhibitors: tetraethylammonium(TEA), glibenclamide(GLI) and 4-aminopyridine(4-AP). To investigate the Ca2+-channel antagonistic effect of HEMA and TEGDMA in different aorta rings, concentration-response curves to CaCl2 were obtained in the absence and presence of the test monomers. Co...
Objectives: The aim was to evaluate the demineralization around and beneath the orthodontic brack... more Objectives: The aim was to evaluate the demineralization around and beneath the orthodontic brackets using 4 adhesive systems and bonding methods. Methods: 80 human molars were randomly divided into 2 groups according to bonding methods (A=enamel around the brackets were kept from contamination of adhesives;B=adhesives were spread over the enamel surface like clinical bonding conditions) and each one was divided into 4 sub-groups. Groups were; 1.Clearfil Protect Bond(CPB)+Transbond XT Light-Cure Adhesive(TXT), 2.GC ORTHO Conditioner+Fuji Ortho LC Capsule, 3.Transbond Plus Self-Etching Primer(TPSEP)+TXT, 4.37% phosphoric acid+Transbond XT Primer+TXT. Additional untreated enamel control group (n=10) was also formed. Thermal and pH-cycles were applied to all experimental specimens. Teeth were sectioned and one of the sections was randomly selected for quantitative elemental analysis with energy dispersive x-ray spectroscopy(EDS). Calcium loss was analyzed at occlusal and cervical (0.5m...
The aim of this study was to determine the extent of calcium removal on root canal dentin after 1... more The aim of this study was to determine the extent of calcium removal on root canal dentin after 17% EDTA, 17% EGTA, 15% EDTAC, and 1% tetracycline-HCl treatment; with or without subsequent use of 2.5% NaOCl. Extracted single-rooted human teeth were bisected longitudinally and the root halves (n=100) were isolated with nail varnish, leaving the root canal exposed. The samples were immersed in the test solutions for 1 and 5 minutes, after which the amount of calcium ion (Ca(2+)) release into the solutions was determined by flame photometry. Regardless of treatment time, all single (treatment solution only) and combined (treatment solution with subsequent NaOCl application) irrigation regimens removed significantly more Ca(2+) than control treatment (distilled water). Compared with other groups, treatment with 17% EDTA and 17% EDTA + 2.5% NaOCl resulted in the maximum amount of Ca(2+) removal from root canal dentin (p<0.05). All combined-treatment groups except 17% EGTA + 2.5% NaOCl...
The aim of this study was to investigate the extent of calcium ion (Ca(2+)) removal on root denti... more The aim of this study was to investigate the extent of calcium ion (Ca(2+)) removal on root dentin after treatment with 1.25% NaOCl, 2.5% NaOCl, 5.25% NaOCl, 2% chlorhexidine (CHX), 2% iodine potassium iodide (IKI), and MTAD in 3 immersion time periods. Extracted human mandibular premolars were bisected longitudinally, and the root halves (n = 70) were isolated with nail varnish, leaving the root canal exposed. The specimens were immersed in the test solutions, during which the amount of Ca(2+) release into the solutions was determined at 5, 10, and 15 minutes by flame photometry. The decalcifying effect of 5%, 2.5%, and 1.25% NaOCl and 2% IKI significantly increased within time (P < .05), with 5% NaOCl extracting the greatest amount of Ca(2+) at all treatment times. For 2% CHX and distilled water, a significant increase in the amount of Ca(2+) extraction from root dentin was only evident at 10 minutes (P < .05) and did not change at 15-minute readings. Between the 5- to 10-mi...
In the last years, several single-bottle dental adhesives have been developed. They are supposed ... more In the last years, several single-bottle dental adhesives have been developed. They are supposed to chemically adhere to dentin, and a liner to protect pulp is not thought to be necessary. In the case of direct pulp capping, hemorrhage control is an important step in success, but little is known about the effect of these new bonding agents on pulpal bleeding. The aim of this study was to evaluate the effect of a new one-step single-bottle adhesive on the smooth muscle contraction of rat uterine muscle and carotid arteries. Efficacy of the bonding agent was compared with that of epinephrine (control), and the contraction forces induced were recorded using a force displacement transducer. Statistical analysis of data revealed that the bonding material produced epinephrine-like concentration-dependent contractions of the smooth muscle, suggesting that one-step bonding agents may act as candidates for hemorrhage control without the use of an additional agent in direct pulp capping proce...
Inflammatory root resorption is a serious complication of dental trauma, which leads to progressi... more Inflammatory root resorption is a serious complication of dental trauma, which leads to progressive loss of the root structure. The purpose of this report was to present a case of perforating inflammatory root resorption in a previously traumatized young incisor tooth with incomplete root development. A 12-year-old girl, who had suffered a traumatic dental injury 4 years earlier, was referred with symptoms of pain and swelling in a permanent maxillary central incisor. The tooth had been root-filled and had thin dentinal walls and a wide open apex. During retreatment, a perforating resorption site was observed on the root's distal aspect. Because the entire root canal filling could not be removed, the resorption site was repaired with white mineral trioxide aggregate in the presence of the remaining gutta-percha. Clinical and radiographic follow-up was conducted for 36 months, demonstrating arrest of the resorptive process, regeneration of the periradicular tissues, and re-establ...
Inflammatory root resorption is a pathologic condition caused by several etiologic factors includ... more Inflammatory root resorption is a pathologic condition caused by several etiologic factors including traumatic dental injury. In this case report, we describe treatment of a maxillary lateral incisor affected by severe, perforating inflammatory root resorption. An 11-year-old patient presented with a previously traumatized, root-filled maxillary lateral incisor associated with pain, mobility and a sinus tract. Radiographic examination revealed a large periradicular lesion involving pathologic resorption of the apical region of the root. After removal of the root canal filling, the tooth was treated with intracanal calcium hydroxide for 2 weeks. The calcium hydroxide dressing was then removed and the entire root canal was filled with mineral trioxide aggregate. The endodontic access cavity was restored with composite resin. After 1 year, advanced osseous healing of the periradicular region had occurred and no clinical symptoms were apparent.
This study investigated the effect of ozone pretreatment on the microleakage and marginal integri... more This study investigated the effect of ozone pretreatment on the microleakage and marginal integrity of pit and fissure sealants placed with or without a self-etch 6th generation adhesive. Freshly-extracted, human third molars were randomly assigned into two main groups (n = 48): Group A: Fissures were pretreated with ozone; Group B: Fissures were left untreated. The teeth were further randomly divided into two subgroups (n = 24/each) so that half of teeth were sealed with a conventional fissure sealant (Fissurit F, Voco, Germany), while the remaining half received the same sealant bonded with a self-etch adhesive (Clearfil Protect Bond, Kuraray, Japan). Following thermal cycling (1000X), the specimens were subjected to dye penetration within 0.5% basic fuchsin for 24h. The extent of dye penetration was measured by image analysis. Kruskal Wallis and Mann-Whitney U tests were used for statistical analysis of the data (p = 0.05). Two randomly-selected sections from each group were obse...
This report describes the 24-month clinical and radiographic outcome of an unintentionally extrud... more This report describes the 24-month clinical and radiographic outcome of an unintentionally extruded mineral trioxide aggregate (MTA) apical plug. A 9 year old boy presented with a previously traumatized, immature central incisor; associated with a large periradicular lesion. During placement of MTA in the treatment of wide open apex, the material was inadvertently extruded into the periapical region upon a sudden movement of the child. No intervention was made, except for obturation of the remaining root canal two weeks later. The radiographic follow up at 12 and 24 months confirmed successful management through the non surgical approach, as evidenced by advanced healing of the periapical lesion and regeneration of the periradicular tissue in the absence of clinical symptoms.
Inversion of premolars is an extremely rare condition, which usually requires extraction. This ca... more Inversion of premolars is an extremely rare condition, which usually requires extraction. This case report describes the inversion of an impacted maxillary second premolar in an 11-year-old male, and the multidisciplinary treatment approach for bringing the tooth into a normal position within the arch. In order to provide sufficient space for surgical reimplantation of the tooth, the mesially-drifted neighbouring maxillary first molar was first endodontically treated, followed by orthodontic distalization of the tooth. The inverted tooth was removed surgically and reimplanted without the use of splints for stabilization. After a 12-month follow-up period, the tooth maintained its vitality without any root resorption. Reimplantation of impacted inverted premolars can be a viable treatment alternative to extraction.
The purpose of this study was to investigate the degree of conversion of a methacrylate-based sea... more The purpose of this study was to investigate the degree of conversion of a methacrylate-based sealer (Epiphany; Pentron Clinical Technologies, Wallingford, CT) with regard to the method of photoactivation, distance from the light-curing unit (LCU), and post-curing time. Freshly mixed Epiphany sealer was dispensed into half-pipe-shaped silicone moulds (n = 48), after which the specimens were photoactivated with one of the following LCUs from the coronal aspect: (1) quartz tungsten halogen/40 seconds and (2) light-emitting diode/20 seconds. In each specimen, the degree of conversion was measured at three different locations (coronal, middle, and apical) using Fourier transform infrared spectroscopy before and after photoactivation. The amount of conversion was approximately 50% after photoactivation and improved by approximately 10% after 15 days. Conversion of Epiphany was not affected by the type of LCU (p > 0.001) or the distance from the LCU (p > 0.001) but showed a signific...
To evaluate the effect of long-term water storage on the microleakage of a fissure sealant applie... more To evaluate the effect of long-term water storage on the microleakage of a fissure sealant applied with or without different bonding agents. Extracted human third molars were randomly assigned into 8 groups (n = 24/each). The occlusal surfaces were sealed with a fluoride fissure sealant material (Helioseal F) after one of the following pretreatments: (1) phosphoric acid etching only; (2) phosphoric acid etching + Single Bond; (3) phosphoric acid etching + Prime & Bond NT; (4) Clearfil SE Bond; (5) FL Bond; (6) One Up Bond F; (7) Prompt L-Pop; (8) Mac Bond II. All specimens were thermocycled (1000X), after which half of them (n=96) were stored in distilled water for 48 h (group A), and the remaining half (n=96) for 48 months (group B). The specimens were immersed in 0.5% basic fuchsin solution, sectioned, and digitally photographed. Microleakage was evaluated quantitatively using an open-source image analysis toolkit (ImageJ), and the data were analyzed statistically. Four-year water...
Intrusive luxation of primary teeth carries a high risk of damage to underlying permanent tooth g... more Intrusive luxation of primary teeth carries a high risk of damage to underlying permanent tooth germs. Ectopic eruption of permanent incisors is an unusual outcome of traumatic injury to their predecessors. In this case report, we describe the multidisciplinary management of the consequences of a primary tooth intrusion that led to severe ectopic eruption of the permanent left central incisor in a horizontal position at the level of the labial sulcus.
Intrusive luxation is a serious dental injury that causes damage to the pulp and supporting struc... more Intrusive luxation is a serious dental injury that causes damage to the pulp and supporting structures of a tooth because of its dislocation into the alveolar process. This paper presents the case of the re-eruption of a severely intruded immature permanent incisor with a crown-root fracture. A 9-year-old boy was referred to the clinic 1 day after a fall. Clinical and radiographic examinations revealed intrusive luxation of the immature left permanent incisor and a crown-root fracture without pulp exposure. Palatal gingivectomy was done 2 weeks later to facilitate re-eruption. Root canal therapy with intracanal calcium hydroxide paste was initiated during the first month owing to severe spontaneous pain. Six months later, the tooth re-erupted to a normal position, after which root canal obturation and a final esthetic restoration were done. The present case demonstrates the possibility of obtaining re-eruption of intruded immature permanent teeth with interim medication (calcium hyd...
Head & Face Medicine (HFM) was launched in August 2005 to provide multidisciplinary science in th... more Head & Face Medicine (HFM) was launched in August 2005 to provide multidisciplinary science in the field of head and face disorders with an open access and open peer review publication platform. The objective of this study is to evaluate the characteristics of submissions, the effectiveness of open peer reviewing, and factors biasing the acceptance or rejection of submitted manuscripts. A 1-year period of submissions and all concomitant journal operations were retrospectively analyzed. The analysis included submission rate, reviewer rate, acceptance rate, article type, and differences in duration for peer reviewing, final decision, publishing, and PubMed inclusion. Statistical analysis included Mann-Whitney U test, Chi-square test, regression analysis, and binary logistic regression. HFM received 126 articles (10.5 articles/month) for consideration in the first year. Submissions have been increasing, but not significantly over time. Peer reviewing was completed for 82 articles and r...
To evaluate the effects of two home-use bleaching gels (Nite-White and Contrast PM) on the surfac... more To evaluate the effects of two home-use bleaching gels (Nite-White and Contrast PM) on the surface roughness of one high-viscosity glass ionomer cement (Fuji IX GP), four polyacid-modified resin-based composites (Dyract AP, F2000, Elan and Compoglass F), two resin-modified glass-ionomer cements (Vitremer and Fuji II LC), a microfilled fluoride-releasing resin-based composite (Tetric) and a microfilled non-fluoridated resin-based composite (Valux) were used as controls. The null hypotheses tested were: (1) the use of bleaching gels would not result in surface roughness values different from those obtained at baseline; (2) differences in the amount of carbamide peroxide present in the gels would not influence surface roughness. Thirty specimen disks (the first 10 used for controls and the balance divided randomly into two groups) were made for each material according to the manufacturers' instructions. Finishing and polishing of the test and control specimens was performed after 2...
In this study, a 35% phosphoric acid gel (3M Scotchbond etchant), a nonrinse etchant (NRC), and t... more In this study, a 35% phosphoric acid gel (3M Scotchbond etchant), a nonrinse etchant (NRC), and two EDTA-containing conditioners (RC-Prep and File-Eze) were tested in vitro for blocking nerve conductance evoked in the rat sciatic nerve after local application. The phosphoric acid gel and NRC completely and irreversibly inhibited conductance. On the other hand, RC-Prep reduced the compound action potentials (cAPs) by 50% in 120 min. With File-Eze, the reduction in cAPs was less than 50% after an application time of 160 min (61.8 ؎ 1.8%). At 160 min the cAPs in the RC-Prep group had been inhibited by 62.4%. These results indicated strong neurotoxic effects of phosphoric acid and NRC when applied directly on exposed pulp in the total etch procedure.
The aim of this study was to compare the cross-sec- tional area of sealer plus voids of Epiphany ... more The aim of this study was to compare the cross-sec- tional area of sealer plus voids of Epiphany sealer surrounding root fillings completed with Resilon cones and laterally compacted gutta-percha. The root canals of extracted human mandibular premolars were pre- pared to a final size of 40 (0.06 taper). The teeth were then randomly assigned into 2 groups (n 12/group)
International Journal of Paediatric Dentistry, 2009
This paper describes the management of self-inflicted trauma by a 4-year-old boy who was mentally... more This paper describes the management of self-inflicted trauma by a 4-year-old boy who was mentally retarded as a result of encephalitis in infancy. There was severe damage to his lower lip, as well as a moderate degree of injury to the skin and nail of his right thumb. Preliminary intervention was made with a mouthguard using silicone elastomeric positioner material, which soon proved ineffective because of poor retention. The problem was overcome successfully through use of a special appliance in which a heat-cured acrylic base was combined with a superstructure made of silicone positioner material retained mechanically with retention loops of 0.7 mm orthodontic wire.
OBJECTIVES: Resin-based dental materials contain various diluent monomers that can interfere with... more OBJECTIVES: Resin-based dental materials contain various diluent monomers that can interfere with vascular function by causing vasorelaxation. In this study, we evaluated the vasoactive potential of hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA), and the possible mechanism(s) of their vascular action on isolated rat aorta. METHODS: Responses of thoracic rat aorta rings were recorded isometrically by using force displacement transducers. After pre-contracting aorta rings, relaxations to HEMA and TEGDMA were recorded in the absence and presence of nitric oxide synthase inhibitor N-nitro-L-arginine methyl ester(L-NAME), cyclooxygenase inhibitor indomethacin, and K+ channel inhibitors: tetraethylammonium(TEA), glibenclamide(GLI) and 4-aminopyridine(4-AP). To investigate the Ca2+-channel antagonistic effect of HEMA and TEGDMA in different aorta rings, concentration-response curves to CaCl2 were obtained in the absence and presence of the test monomers. Co...
Objectives: The aim was to evaluate the demineralization around and beneath the orthodontic brack... more Objectives: The aim was to evaluate the demineralization around and beneath the orthodontic brackets using 4 adhesive systems and bonding methods. Methods: 80 human molars were randomly divided into 2 groups according to bonding methods (A=enamel around the brackets were kept from contamination of adhesives;B=adhesives were spread over the enamel surface like clinical bonding conditions) and each one was divided into 4 sub-groups. Groups were; 1.Clearfil Protect Bond(CPB)+Transbond XT Light-Cure Adhesive(TXT), 2.GC ORTHO Conditioner+Fuji Ortho LC Capsule, 3.Transbond Plus Self-Etching Primer(TPSEP)+TXT, 4.37% phosphoric acid+Transbond XT Primer+TXT. Additional untreated enamel control group (n=10) was also formed. Thermal and pH-cycles were applied to all experimental specimens. Teeth were sectioned and one of the sections was randomly selected for quantitative elemental analysis with energy dispersive x-ray spectroscopy(EDS). Calcium loss was analyzed at occlusal and cervical (0.5m...
The aim of this study was to determine the extent of calcium removal on root canal dentin after 1... more The aim of this study was to determine the extent of calcium removal on root canal dentin after 17% EDTA, 17% EGTA, 15% EDTAC, and 1% tetracycline-HCl treatment; with or without subsequent use of 2.5% NaOCl. Extracted single-rooted human teeth were bisected longitudinally and the root halves (n=100) were isolated with nail varnish, leaving the root canal exposed. The samples were immersed in the test solutions for 1 and 5 minutes, after which the amount of calcium ion (Ca(2+)) release into the solutions was determined by flame photometry. Regardless of treatment time, all single (treatment solution only) and combined (treatment solution with subsequent NaOCl application) irrigation regimens removed significantly more Ca(2+) than control treatment (distilled water). Compared with other groups, treatment with 17% EDTA and 17% EDTA + 2.5% NaOCl resulted in the maximum amount of Ca(2+) removal from root canal dentin (p<0.05). All combined-treatment groups except 17% EGTA + 2.5% NaOCl...
The aim of this study was to investigate the extent of calcium ion (Ca(2+)) removal on root denti... more The aim of this study was to investigate the extent of calcium ion (Ca(2+)) removal on root dentin after treatment with 1.25% NaOCl, 2.5% NaOCl, 5.25% NaOCl, 2% chlorhexidine (CHX), 2% iodine potassium iodide (IKI), and MTAD in 3 immersion time periods. Extracted human mandibular premolars were bisected longitudinally, and the root halves (n = 70) were isolated with nail varnish, leaving the root canal exposed. The specimens were immersed in the test solutions, during which the amount of Ca(2+) release into the solutions was determined at 5, 10, and 15 minutes by flame photometry. The decalcifying effect of 5%, 2.5%, and 1.25% NaOCl and 2% IKI significantly increased within time (P < .05), with 5% NaOCl extracting the greatest amount of Ca(2+) at all treatment times. For 2% CHX and distilled water, a significant increase in the amount of Ca(2+) extraction from root dentin was only evident at 10 minutes (P < .05) and did not change at 15-minute readings. Between the 5- to 10-mi...
In the last years, several single-bottle dental adhesives have been developed. They are supposed ... more In the last years, several single-bottle dental adhesives have been developed. They are supposed to chemically adhere to dentin, and a liner to protect pulp is not thought to be necessary. In the case of direct pulp capping, hemorrhage control is an important step in success, but little is known about the effect of these new bonding agents on pulpal bleeding. The aim of this study was to evaluate the effect of a new one-step single-bottle adhesive on the smooth muscle contraction of rat uterine muscle and carotid arteries. Efficacy of the bonding agent was compared with that of epinephrine (control), and the contraction forces induced were recorded using a force displacement transducer. Statistical analysis of data revealed that the bonding material produced epinephrine-like concentration-dependent contractions of the smooth muscle, suggesting that one-step bonding agents may act as candidates for hemorrhage control without the use of an additional agent in direct pulp capping proce...
Inflammatory root resorption is a serious complication of dental trauma, which leads to progressi... more Inflammatory root resorption is a serious complication of dental trauma, which leads to progressive loss of the root structure. The purpose of this report was to present a case of perforating inflammatory root resorption in a previously traumatized young incisor tooth with incomplete root development. A 12-year-old girl, who had suffered a traumatic dental injury 4 years earlier, was referred with symptoms of pain and swelling in a permanent maxillary central incisor. The tooth had been root-filled and had thin dentinal walls and a wide open apex. During retreatment, a perforating resorption site was observed on the root's distal aspect. Because the entire root canal filling could not be removed, the resorption site was repaired with white mineral trioxide aggregate in the presence of the remaining gutta-percha. Clinical and radiographic follow-up was conducted for 36 months, demonstrating arrest of the resorptive process, regeneration of the periradicular tissues, and re-establ...
Inflammatory root resorption is a pathologic condition caused by several etiologic factors includ... more Inflammatory root resorption is a pathologic condition caused by several etiologic factors including traumatic dental injury. In this case report, we describe treatment of a maxillary lateral incisor affected by severe, perforating inflammatory root resorption. An 11-year-old patient presented with a previously traumatized, root-filled maxillary lateral incisor associated with pain, mobility and a sinus tract. Radiographic examination revealed a large periradicular lesion involving pathologic resorption of the apical region of the root. After removal of the root canal filling, the tooth was treated with intracanal calcium hydroxide for 2 weeks. The calcium hydroxide dressing was then removed and the entire root canal was filled with mineral trioxide aggregate. The endodontic access cavity was restored with composite resin. After 1 year, advanced osseous healing of the periradicular region had occurred and no clinical symptoms were apparent.
This study investigated the effect of ozone pretreatment on the microleakage and marginal integri... more This study investigated the effect of ozone pretreatment on the microleakage and marginal integrity of pit and fissure sealants placed with or without a self-etch 6th generation adhesive. Freshly-extracted, human third molars were randomly assigned into two main groups (n = 48): Group A: Fissures were pretreated with ozone; Group B: Fissures were left untreated. The teeth were further randomly divided into two subgroups (n = 24/each) so that half of teeth were sealed with a conventional fissure sealant (Fissurit F, Voco, Germany), while the remaining half received the same sealant bonded with a self-etch adhesive (Clearfil Protect Bond, Kuraray, Japan). Following thermal cycling (1000X), the specimens were subjected to dye penetration within 0.5% basic fuchsin for 24h. The extent of dye penetration was measured by image analysis. Kruskal Wallis and Mann-Whitney U tests were used for statistical analysis of the data (p = 0.05). Two randomly-selected sections from each group were obse...
This report describes the 24-month clinical and radiographic outcome of an unintentionally extrud... more This report describes the 24-month clinical and radiographic outcome of an unintentionally extruded mineral trioxide aggregate (MTA) apical plug. A 9 year old boy presented with a previously traumatized, immature central incisor; associated with a large periradicular lesion. During placement of MTA in the treatment of wide open apex, the material was inadvertently extruded into the periapical region upon a sudden movement of the child. No intervention was made, except for obturation of the remaining root canal two weeks later. The radiographic follow up at 12 and 24 months confirmed successful management through the non surgical approach, as evidenced by advanced healing of the periapical lesion and regeneration of the periradicular tissue in the absence of clinical symptoms.
Inversion of premolars is an extremely rare condition, which usually requires extraction. This ca... more Inversion of premolars is an extremely rare condition, which usually requires extraction. This case report describes the inversion of an impacted maxillary second premolar in an 11-year-old male, and the multidisciplinary treatment approach for bringing the tooth into a normal position within the arch. In order to provide sufficient space for surgical reimplantation of the tooth, the mesially-drifted neighbouring maxillary first molar was first endodontically treated, followed by orthodontic distalization of the tooth. The inverted tooth was removed surgically and reimplanted without the use of splints for stabilization. After a 12-month follow-up period, the tooth maintained its vitality without any root resorption. Reimplantation of impacted inverted premolars can be a viable treatment alternative to extraction.
The purpose of this study was to investigate the degree of conversion of a methacrylate-based sea... more The purpose of this study was to investigate the degree of conversion of a methacrylate-based sealer (Epiphany; Pentron Clinical Technologies, Wallingford, CT) with regard to the method of photoactivation, distance from the light-curing unit (LCU), and post-curing time. Freshly mixed Epiphany sealer was dispensed into half-pipe-shaped silicone moulds (n = 48), after which the specimens were photoactivated with one of the following LCUs from the coronal aspect: (1) quartz tungsten halogen/40 seconds and (2) light-emitting diode/20 seconds. In each specimen, the degree of conversion was measured at three different locations (coronal, middle, and apical) using Fourier transform infrared spectroscopy before and after photoactivation. The amount of conversion was approximately 50% after photoactivation and improved by approximately 10% after 15 days. Conversion of Epiphany was not affected by the type of LCU (p > 0.001) or the distance from the LCU (p > 0.001) but showed a signific...
To evaluate the effect of long-term water storage on the microleakage of a fissure sealant applie... more To evaluate the effect of long-term water storage on the microleakage of a fissure sealant applied with or without different bonding agents. Extracted human third molars were randomly assigned into 8 groups (n = 24/each). The occlusal surfaces were sealed with a fluoride fissure sealant material (Helioseal F) after one of the following pretreatments: (1) phosphoric acid etching only; (2) phosphoric acid etching + Single Bond; (3) phosphoric acid etching + Prime & Bond NT; (4) Clearfil SE Bond; (5) FL Bond; (6) One Up Bond F; (7) Prompt L-Pop; (8) Mac Bond II. All specimens were thermocycled (1000X), after which half of them (n=96) were stored in distilled water for 48 h (group A), and the remaining half (n=96) for 48 months (group B). The specimens were immersed in 0.5% basic fuchsin solution, sectioned, and digitally photographed. Microleakage was evaluated quantitatively using an open-source image analysis toolkit (ImageJ), and the data were analyzed statistically. Four-year water...
Intrusive luxation of primary teeth carries a high risk of damage to underlying permanent tooth g... more Intrusive luxation of primary teeth carries a high risk of damage to underlying permanent tooth germs. Ectopic eruption of permanent incisors is an unusual outcome of traumatic injury to their predecessors. In this case report, we describe the multidisciplinary management of the consequences of a primary tooth intrusion that led to severe ectopic eruption of the permanent left central incisor in a horizontal position at the level of the labial sulcus.
Intrusive luxation is a serious dental injury that causes damage to the pulp and supporting struc... more Intrusive luxation is a serious dental injury that causes damage to the pulp and supporting structures of a tooth because of its dislocation into the alveolar process. This paper presents the case of the re-eruption of a severely intruded immature permanent incisor with a crown-root fracture. A 9-year-old boy was referred to the clinic 1 day after a fall. Clinical and radiographic examinations revealed intrusive luxation of the immature left permanent incisor and a crown-root fracture without pulp exposure. Palatal gingivectomy was done 2 weeks later to facilitate re-eruption. Root canal therapy with intracanal calcium hydroxide paste was initiated during the first month owing to severe spontaneous pain. Six months later, the tooth re-erupted to a normal position, after which root canal obturation and a final esthetic restoration were done. The present case demonstrates the possibility of obtaining re-eruption of intruded immature permanent teeth with interim medication (calcium hyd...
Head & Face Medicine (HFM) was launched in August 2005 to provide multidisciplinary science in th... more Head & Face Medicine (HFM) was launched in August 2005 to provide multidisciplinary science in the field of head and face disorders with an open access and open peer review publication platform. The objective of this study is to evaluate the characteristics of submissions, the effectiveness of open peer reviewing, and factors biasing the acceptance or rejection of submitted manuscripts. A 1-year period of submissions and all concomitant journal operations were retrospectively analyzed. The analysis included submission rate, reviewer rate, acceptance rate, article type, and differences in duration for peer reviewing, final decision, publishing, and PubMed inclusion. Statistical analysis included Mann-Whitney U test, Chi-square test, regression analysis, and binary logistic regression. HFM received 126 articles (10.5 articles/month) for consideration in the first year. Submissions have been increasing, but not significantly over time. Peer reviewing was completed for 82 articles and r...
To evaluate the effects of two home-use bleaching gels (Nite-White and Contrast PM) on the surfac... more To evaluate the effects of two home-use bleaching gels (Nite-White and Contrast PM) on the surface roughness of one high-viscosity glass ionomer cement (Fuji IX GP), four polyacid-modified resin-based composites (Dyract AP, F2000, Elan and Compoglass F), two resin-modified glass-ionomer cements (Vitremer and Fuji II LC), a microfilled fluoride-releasing resin-based composite (Tetric) and a microfilled non-fluoridated resin-based composite (Valux) were used as controls. The null hypotheses tested were: (1) the use of bleaching gels would not result in surface roughness values different from those obtained at baseline; (2) differences in the amount of carbamide peroxide present in the gels would not influence surface roughness. Thirty specimen disks (the first 10 used for controls and the balance divided randomly into two groups) were made for each material according to the manufacturers' instructions. Finishing and polishing of the test and control specimens was performed after 2...
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Papers by Zafer Cehreli