Papers by Ricardo Oliveira
Epilepsy & Behavior, 2003
In this study we present data from a survey that aimed to assess the physical activity of a sampl... more In this study we present data from a survey that aimed to assess the physical activity of a sample of adult outpatients with epilepsy. One hundred adult outpatients of both sexes with epilepsy answered a survey addressing exercise habits. Fifty-eight males and forty-two females participated in this study. The mean age of onset of seizures was 18.6 years and the mean duration of epilepsy was 16.1 years. Sixty patients had controlled or rare seizures, 8 infrequent seizures, 17 frequent seizures, and 11 very frequent seizures. Eighty-six had partial epilepsy and only 3 had abnormal neurological examinations. Of the total, 51 engaged in physical activity, 85 did not believe that sports precipitate seizures, and 15 were forbidden by their physicians to engage in physical activities. Moreover, 14 were cautioned against participation in sports by their relatives and friends. Eight-four patients had never experienced seizures during physical exercise, 36 believed that physical activity has a positive influence on treatment, and only 1 related injuries associated with seizures. Forty-five are afraid of having seizures during exercise because the seizures might attract the attention of others and they would make fools of themselves. Our data show that although most of our patients do not regularly engage in physical activity, they believe that it might improve medical treatment.
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Revista do Colégio Brasileiro de Cirurgiões
To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileosto... more To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileostomies. We analyzed epidemiological data, postoperative complications, morbidity and mortality of patients who underwent operations for closure of loop colostomies and ileostomies. We excluded patients whose data could not be obtained from the files and operations that required laparotomy for closure. 88 patients were operated on, five being excluded. We evaluated the data of 83 patients, 56 patients with colostomies (group C) and 27 with ileostomies (group I). Males predominated in both groups (C = 71.9% and I = 57.7%). In group C the most common indication for making the stoma was abdominal trauma (43.9%) and in group I it was protecting a colorectal anastomosis (57.6%). The rate of anastomotic dehiscence in group C was 3.5% and in group I 19.2%. Morbidity was higher in group I than in group C (30.7% vs. 12.2%). There was one death in group I. The study suggests that morbidity associated...
Revista do Colégio Brasileiro de Cirurgiões
To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileosto... more To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileostomies. We analyzed epidemiological data, postoperative complications, morbidity and mortality of patients who underwent operations for closure of loop colostomies and ileostomies. We excluded patients whose data could not be obtained from the files and operations that required laparotomy for closure. 88 patients were operated on, five being excluded. We evaluated the data of 83 patients, 56 patients with colostomies (group C) and 27 with ileostomies (group I). Males predominated in both groups (C = 71.9% and I = 57.7%). In group C the most common indication for making the stoma was abdominal trauma (43.9%) and in group I it was protecting a colorectal anastomosis (57.6%). The rate of anastomotic dehiscence in group C was 3.5% and in group I 19.2%. Morbidity was higher in group I than in group C (30.7% vs. 12.2%). There was one death in group I. The study suggests that morbidity associated...
Revista do Colégio Brasileiro de Cirurgiões
To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileosto... more To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileostomies. We analyzed epidemiological data, postoperative complications, morbidity and mortality of patients who underwent operations for closure of loop colostomies and ileostomies. We excluded patients whose data could not be obtained from the files and operations that required laparotomy for closure. 88 patients were operated on, five being excluded. We evaluated the data of 83 patients, 56 patients with colostomies (group C) and 27 with ileostomies (group I). Males predominated in both groups (C = 71.9% and I = 57.7%). In group C the most common indication for making the stoma was abdominal trauma (43.9%) and in group I it was protecting a colorectal anastomosis (57.6%). The rate of anastomotic dehiscence in group C was 3.5% and in group I 19.2%. Morbidity was higher in group I than in group C (30.7% vs. 12.2%). There was one death in group I. The study suggests that morbidity associated...
Revista do Colégio Brasileiro de Cirurgiões
To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileosto... more To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileostomies. We analyzed epidemiological data, postoperative complications, morbidity and mortality of patients who underwent operations for closure of loop colostomies and ileostomies. We excluded patients whose data could not be obtained from the files and operations that required laparotomy for closure. 88 patients were operated on, five being excluded. We evaluated the data of 83 patients, 56 patients with colostomies (group C) and 27 with ileostomies (group I). Males predominated in both groups (C = 71.9% and I = 57.7%). In group C the most common indication for making the stoma was abdominal trauma (43.9%) and in group I it was protecting a colorectal anastomosis (57.6%). The rate of anastomotic dehiscence in group C was 3.5% and in group I 19.2%. Morbidity was higher in group I than in group C (30.7% vs. 12.2%). There was one death in group I. The study suggests that morbidity associated...
Revista do Colégio Brasileiro de Cirurgiões
To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileosto... more To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileostomies. We analyzed epidemiological data, postoperative complications, morbidity and mortality of patients who underwent operations for closure of loop colostomies and ileostomies. We excluded patients whose data could not be obtained from the files and operations that required laparotomy for closure. 88 patients were operated on, five being excluded. We evaluated the data of 83 patients, 56 patients with colostomies (group C) and 27 with ileostomies (group I). Males predominated in both groups (C = 71.9% and I = 57.7%). In group C the most common indication for making the stoma was abdominal trauma (43.9%) and in group I it was protecting a colorectal anastomosis (57.6%). The rate of anastomotic dehiscence in group C was 3.5% and in group I 19.2%. Morbidity was higher in group I than in group C (30.7% vs. 12.2%). There was one death in group I. The study suggests that morbidity associated...
Revista do Colégio Brasileiro de Cirurgiões
To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileosto... more To evaluate the morbidity and mortality of operations for closure of loop colostomies and ileostomies. We analyzed epidemiological data, postoperative complications, morbidity and mortality of patients who underwent operations for closure of loop colostomies and ileostomies. We excluded patients whose data could not be obtained from the files and operations that required laparotomy for closure. 88 patients were operated on, five being excluded. We evaluated the data of 83 patients, 56 patients with colostomies (group C) and 27 with ileostomies (group I). Males predominated in both groups (C = 71.9% and I = 57.7%). In group C the most common indication for making the stoma was abdominal trauma (43.9%) and in group I it was protecting a colorectal anastomosis (57.6%). The rate of anastomotic dehiscence in group C was 3.5% and in group I 19.2%. Morbidity was higher in group I than in group C (30.7% vs. 12.2%). There was one death in group I. The study suggests that morbidity associated...
Acta Cirurgica Brasileira, 2006
ABSTRACT OBJETIVO: Propor uma padronização, no idioma inglês, na formatação da citação da sede da... more ABSTRACT OBJETIVO: Propor uma padronização, no idioma inglês, na formatação da citação da sede da pesquisa. MÉTODOS: A partir das três publicações mais recentes dos 20 primeiros periódicos disponíveis no Portal Brasileiro de Informação Científica - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), com maior fator de impacto durante a ano de 2004, segundo levantamento na base de dados ISI Web of Knowledge Journal Citation Reports no biênio 2004-2005, extraíram-se os formatos das citações das sedes de pesquisa. Realizou-se uma analogia ao escalonamento hierárquico institucional da Universidade Federal de São Paulo (UNIFESP), e os formatos mais freqüentes, no idioma inglês, foram adotados como padrão a ser sugerido para citar as sedes de pesquisa ao envio dos artigos. RESULTADOS: Em relação à citação "Departamento", padronizou-se "Department of ..." (sendo "..." o nome em inglês do Departamento), à citação "Programa de Pós-Graduação" "... Program", "Disciplina" "Division of ...", "Órgãos, Grupos e Associações" "... Group", "Setor" "Section of ...", "Centro" "Center for ...", "Unidade" "... Unit" "Instituto" "Institute of ...", "Laboratório" "Laboratory of ..." e "Grupo" "Group of ...".
Neste trabal ho descreveremos os primeiros resultados de uma ação de formação continuada de profe... more Neste trabal ho descreveremos os primeiros resultados de uma ação de formação continuada de professores de ciências do ensino fundamental e professores de física, biologia e química do ensino médio, tendo como âncora a teoria vygotskyana, utilizando kits de atividades experimentais, e sua correlação com brinquedos científicos interativos, propositalmente dispostos num Centro de Ciências com formas e cores que permitam medir pedagogicamente os efeitos de aprendizagem em ações integradas de ensino. Cada vez mais precisamo s conscientizar não só a comunidade acadêmica, mas também a sociedade em geral, da importância dos conhecimento s científicos em nossas vidas. É fundamental qualquer pessoa reunir minimamente condições de opinar sobre questões do cotidiano que nos influenciam diretamente em diversas situações, para assim nossas ações serem sempre direcionadas para um comportamento de autênticos cidadãos críticos. Para contribuir com essa importante e necessária pretensão faz-se necessário a existência de espaços de educação alternativos. Estes espaços não formais de ensino podem se tornar grandes aliados na busca por um autêntico e frutífero apoio na questão de consolidar uma verdadeira cultura de divulgação científica nas escolas e na sociedade. Nesse sentido, com o intuito inicial de poder auxiliar a escola básica, principalmente no que diz respeito à formação continuada de professores de ciências e áreas afins, foi inaugurado em agosto de 2006 o Centro de Ciências da Universidade Federal de Juiz de Fora. Várias atividades estão sendo desenvolvidas no Centro de Ciências da UFJF, como visitas de escolas, atividades de observação astronômica, exibições de um planetário inflável, experimentos de laboratório, exposições interativas de curta e longa duração, e cursos para professo res da rede básica , entre outras iniciativas de divulgação e popularização da ciência.
This study aimed to evaluate the response of photosynthesis (A), given by photosynthetic O2 evolu... more This study aimed to evaluate the response of photosynthesis (A), given by photosynthetic O2 evolution, to increasing temperature from 25 to 50ºC in sweet orange (Citrus sinensis (L.) Osbeck) leaf discs under non-photorespiring conditions. In order to evaluate the response of gross photosynthesis to temperature and the balance between photosynthetic and respiratory activities, respiration (Rd) rates were also measured, i.e.
Clinical physiology and functional imaging, Jan 16, 2015
Ageing is associated with changes in body composition that may result in sarcopenic obesity (SO).... more Ageing is associated with changes in body composition that may result in sarcopenic obesity (SO). Interleukin-6 (IL-6) and C-reactive protein (CRP) are important inflammatory markers related to ageing. SO has been examined as an important public health problem, but its association with inflammatory markers has yet to be investigated. The aim of this study was to investigate the association between SO-related phenotypes and inflammatory markers in postmenopausal women. A total of 130 women (66·7 ± 5·2 years) underwent body composition evaluation using dual-energy X-ray absorptiometry. Volunteers were classified according to a SO definition previously described in the literature. Waist circumference (WC) and handgrip strength (HG) were also measured. Blood samples were collected for CRP, tumour necrosis factor and IL-6 measurements. All the inflammatory markers were higher in SO individuals when compared to non-SO; however, only IL-6 reached statistical significance (median 3·34 versu...
Journal of Science and Medicine in Sport, 2014
Please cite this article in press as: Silva NL, et al. Influence of strength training variables o... more Please cite this article in press as: Silva NL, et al. Influence of strength training variables on strength gains in adults over 55 years-old: A meta-analysis of dose-response relationships. J Sci Med Sport (2013), http://dx.
Journal of Cancer Research and Clinical Oncology, 1995
Chemotherapy with oxazaphosphorines, such as ifosfamide, is often limited by unacceptable urotoxi... more Chemotherapy with oxazaphosphorines, such as ifosfamide, is often limited by unacceptable urotoxicity. Without uroprotection hemorrhagic cystitis becomes dose-limiting. Mesna, a thiol compound, is a drug able to bind the toxic metabolites, forming nontoxic compounds in the urine. A total of 122 patients were enrolled in this study and 228 chemotherapy cycles with an ifosfamide-containing regimen were performed (225 evaluable). Mesna was given at the same total dose as the ifosfamide in all arms. On arm A, mesna was given i. v. in equal doses 15 min before and 4 h and 8 h following the ifosfamide dose. On arm B, mesna was given in three equivalent doses 15 min before (i.v.) and 4 h (i.v.) and 8 h (p.o., double dose) following ifosfamide. On arm C, mesna was given i.v. in two equal doses given 15 min before and 4 h following. The incidence of urotoxicity was very low (lower than 15%) in the three arms, 0% in A, 1.36% in B and 2.70% in C. All three arms were equally efficient. Schedule C was considered superior to the others, since it was equally effective, simpler and more convenient.
Pharmacology Biochemistry and Behavior, 2004
Partial sleep deprivation is clinically associated with fatigue, depressive symptoms and reduced ... more Partial sleep deprivation is clinically associated with fatigue, depressive symptoms and reduced memory. Previously, it has been demonstrated that venlafaxine, an atypical antidepressant, increases the levels of noradrenaline and serotonin in rat hippocampus. The aim of this study was to evaluate the effects of venlafaxine on depression, anxiety, locomotor activity and memory in a model of REM sleep (REMs) deprivation in rats. We have also studied the influence of venlafaxine on monoamine levels in the striatum. Six groups of animals (N=20 each) were treated with saline or venlafaxine (1 or 10 mg/kg) during 10 days, submitted or not to REMs deprivation and studied with the forced swimming test of Porsolt (STP), plus-maze, passive avoidance and open-field tests right after sleep deprivation. Animals were also studied for passive avoidance 24 h later (rebound period). Brain samples for monoamine measurements were collected either immediately after REMs deprivation or after 24 h. Both REMs deprivation and venlafaxine showed an antidepressant effect. An anxiolytic effect was also observed after REMs deprivation. Previous treatment with venlafaxine blocked the antidepressant and anxiolytic effects of REMs deprivation. REMs deprivation alone and treatment with venlafaxine 10 mg/kg increased locomotor activity, and this effect was inhibited by venlafaxine in REMs deprived rats. Both venlafaxine treatment and REMs deprivation induced weight loss. Venlafaxine treatment, but not REMs deprivation, induced an increase in striatal dopamine (DA) levels. The combination of REMs deprivation and venlafaxine treatment was associated with an increase in serotonin turnover 24 h after rebound sleep. In this study, venlafaxine treatment hindered most behavioral effects of REMs deprivation and was associated with an interference on dopamine and serotonin systems in the striatum.
Journal of Nanobiotechnology, 2011
Background: Rhodium (II) citrate (Rh 2 (H 2 cit) 4 ) has significant antitumor, cytotoxic, and cy... more Background: Rhodium (II) citrate (Rh 2 (H 2 cit) 4 ) has significant antitumor, cytotoxic, and cytostatic activity on Ehrlich ascite tumor. Although toxic to normal cells, its lower toxicity when compared to carboxylate analogues of rhodium (II) indicates Rh 2 (H 2 cit) 4 as a promising agent for chemotherapy. Nevertheless, few studies have been performed to explore this potential. Superparamagnetic particles of iron oxide (SPIOs) represent an attractive platform as carriers in drug delivery systems (DDS) because they can present greater specificity to tumor cells than normal cells. Thus, the association between Rh 2 (H 2 cit) 4 and SPIOs can represent a strategy to enhance the former's therapeutic action. In this work, we report the cytotoxicity of free rhodium (II) citrate (Rh 2 (H 2 cit) 4 ) and rhodium (II) citrate-loaded maghemite nanoparticles or magnetoliposomes, used as drug delivery systems, on both normal and carcinoma breast cell cultures.
European Journal of Cardiovascular Prevention & Rehabilitation, 2009
Background A graded but nonlinear relationship exists between fitness and mortality, with the gre... more Background A graded but nonlinear relationship exists between fitness and mortality, with the greatest mortality differences occurring between the least-fit (first, Q1) and the next-least-fit (second, Q2) quintiles of fitness. The purpose of this study was to compare clinical characteristics, exercise test responses, and physical activity (PA) patterns in Q1 versus Q2 in patients with cardiovascular disease (CVD). Design Observational retrospective study. Methods A total of 5101 patients with a history of CVD underwent clinical treadmill testing and were followed up for 9.1 ± 5.5 years. Patients were classified into quintiles of exercise capacity measured in metabolic equivalents. Clinical characteristics, treadmill test results, and recreational PA patterns were compared between Q1 (n = 923) and Q2 (n = 929). Results Q1 had a nearly two-fold increase in age-adjusted relative risk of cardiovascular mortality compared with Q2 (hazard ratio: 3.79 vs. 2.04, P < 0.05; reference: fittest quintile). Q1 patients were older, had more extensive use of medications, and were more likely to have a history of typical angina (35 vs. 28%), myocardial infarction (30 vs. 24%), chronic heart failure (25 vs. 14%), claudication (15 vs. 9%) and stroke (9 vs. 6%) compared with Q2 (all comparisons: P < 0.05). Recent and lifetime recreational PA was not different between the two groups. Conclusion Greater severity of disease in the least-fit versus the next-least-fit quintile likely contributes to but cannot fully explain marked differences in mortality rates in CVD patients. To achieve potential survival benefits, our results suggest that unfit CVD patients should engage in exercise programs of sufficient volume and intensity to improve fitness. Eur J Cardiovasc Prev
The American Journal of Cardiology, 2009
There is scarce information regarding the prognostic utility of peak exercise oxygen pulse (peak ... more There is scarce information regarding the prognostic utility of peak exercise oxygen pulse (peak O 2 pulse), a surrogate for stroke volume, in patients with heart failure (HF). From patients with HF underwent cardiopulmonary exercise testing. The ability of peak oxygen uptake (VO 2 ) and peak O 2 pulse to predict cardiac events was examined. Peak O 2 pulse was calculated by dividing peak VO 2 by heart rate at the time peak VO 2 was achieved and was expressed in both milliliters per beat and as a percentage achieved of the age-predicted value. There were 212 cardiac events (176 deaths, 26 transplantations, and 10 left ventricular assist device implantations) over a mean of 28 ؎ 26 months of follow-up. Peak VO 2 and age-predicted peak O 2 pulse were demonstrated by univariate and multivariate Cox regression analyses to be independent predictors of mortality (p <0.001). The optimal cut points for peak VO 2 and age-predicted peak O 2 pulse (<14.3 and >14.3 [mL/kg ؊1 /min ؊1 ] and <85% and >85%, respectively) were established by areas under the receiver-operating characteristic curves. Patients exhibiting abnormalities for both responses had 4.8-fold (95% confidence interval 2.7 to 8.5) and 6.7-fold (95% confidence interval 4.1 to 11.1) higher risks for mortality and cardiac events, respectively, than those whose responses were normal. Age-predicted peak O 2 pulse also predicted mortality in patients in the intermediate range of peak VO 2 (10 to 14 (mL/kg ؊1 / min ؊1 )). The 3-year mortality rate for patients in this range who had age-predicted peak O 2 pulse values <85% was even slightly higher than those with peak VO 2 <10.1 (mL/ kg ؊1 /min ؊1 ). In conclusion, age-predicted peak O 2 pulse was a strong and independent predictor of cardiac mortality and complemented peak VO 2 in predicting risk in patients with HF. Published by Elsevier
European Journal of Cardiovascular Prevention & Rehabilitation, 2009
Background Maximal oxygen pulse (O 2 pulse) mirrors the stroke volume response to exercise, and s... more Background Maximal oxygen pulse (O 2 pulse) mirrors the stroke volume response to exercise, and should therefore be a strong predictor of mortality. Limited and conflicting data are, however, available on this issue. Methods Nine hundred forty-eight participants, classified as those with cardiopulmonary disease (CPD) and those without (non-CPD), underwent cardiopulmonary exercise testing (CPX) for clinical reasons between 1993 and 2003. The ability of maximal O 2 pulse and maximal oxygen uptake (peak VO 2 ) to predict mortality was investigated using proportional hazards and Akaike information criterion analyses. All-cause mortality was the endpoint. Results Over a mean follow-up of 6.3 ± 3.2 years, there were 126 deaths. Maximal O 2 pulse, expressed in either absolute or relative to age-predicted terms, and peak VO 2 were significant and independent predictors of mortality in those with and without CPD (P < 0.04). Akaike information criterion analysis revealed that the model including both maximal O 2 pulse and peak VO 2 had the highest accuracy for predicting mortality. The optimal cut-points for O 2 pulse and peak VO 2 ( < 12; Z 12 ml/beat and < 16; Z 16 ml/(kg . min) respectively) were established by the area under the receiver-operating-characteristic curve. The relative risks of mortality were 3.4 and 2.2 (CPD and non-CPD, respectively) among participants with both maximal O 2 pulse and peak VO 2 responses below these cut-points compared with participants with both responses above these cut-points. Conclusion These results indicate that maximal O 2 pulse is a significant predictor of mortality in patients with and without CPD. The addition of absolute and relative O 2 pulse data provides complementary information for risk-stratifying heterogeneous participants referred for CPX and should be routinely included in the CPX report. Eur J Cardiovasc Prev
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Papers by Ricardo Oliveira