Papers by Oskar Hagströmer
Background: In order to increase access to antiretroviral therapy (ART) in HIV-infected children,... more Background: In order to increase access to antiretroviral therapy (ART) in HIV-infected children, paediatric HIV care has been introduced in health centres in Ethiopia, where patients are managed by health professionals with limited training. Objective: To compare outcomes of paediatric HIV care in hospital and health centre clinics and to determine risk factors for death and loss to follow-up (LTFU). Design: Retrospective comparison of patient characteristics and outcomes among children managed in a public hospital and all five public health centres in the uptake area. Results: Among 1,960 patients (health centres 572, hospital clinic 1,388), 34% were lost to follow-up, 2% died, 14% were transferred out, and 46% remained in care. Children initiating ART in the hospital clinic had lower median CD4 cell counts (age B1 year: 575 vs. 1,183 cells/mm 3 , p00.024; age 1Á5 years: 370 vs. 598 cells/mm 3 , p B0.001; age 5 years: 186 vs. 259 cells/mm 3 , pB0.001), and a higher proportion were B1 year of age (22% vs. 15%, p 00.025). ART initiation rates and retention in care were similar between children managed in health centres and in the hospital clinic (36% vs. 37% and 47% vs. 46%, respectively). Among patients starting ART, mortality was associated with age B1 year [hazard ratio (HR) 12.0; 95% confidence interval (CI): 3.5, 41]. LTFU was associated with CD4 cell counts B350 cells/mm 3 (HR 1.8; 95% CI: 1.2, 3.0), weightfor-age z-scores below (4
European Journal of Cancer, 2011
Risk Metastasis A B S T R A C T Increasing incidence of testicular germ cell cancer (TGCC) is mos... more Risk Metastasis A B S T R A C T Increasing incidence of testicular germ cell cancer (TGCC) is most probably related to environment and lifestyle. However, an underlying genetic predisposition may play a role and since sex steroids are assumed to be important for the rise and progression of TGCC, a study of androgen receptor (AR) gene polymorphisms in relation to the risk, histological type and progression of TGCC was undertaken.
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Papers by Oskar Hagströmer