Papers by Nevenka Pavlovic
Zdravstvena zaštita, 2016
Zdravstvena zaštita, 2017
Zdravstvena zastita, 2017
епидемиолог, Градски завод за јавно здравље Београд. 2 Мр сц. мед. др Соња Гиљача, епидемиолог, Г... more епидемиолог, Градски завод за јавно здравље Београд. 2 Мр сц. мед. др Соња Гиљача, епидемиолог, Градски завод за јавно здравље Београд. 3 Ивана Беговић Лазаревић, епидемиолог, Градски завод за јавно здравље Београд. 4 Мр сц. мед. др Славица Марис, епидемиолог, Градски завод за јавно здравље Београд. 5 Мр сц. мед. др Невенка Павловић, епидемиолог, Градски завод за јавно здравље Београд.
Aspects of Lyme Borreliosis, 1993
Our prospective study covered 1093 patients with epidemiological features and demonstrable clinic... more Our prospective study covered 1093 patients with epidemiological features and demonstrable clinical manifestations of Lyme borreliosis from 1987 to 1992. Basic criteria for the inclusion of our patients in the study were: tick bite, erythema migrans and antibodies to B. burgdorferi in each patient's serum. Various clinical manifestations were found un 1034 (94.6%) patients out of whom 829 (80.2%) had a history of tick bite, 901 (87.1%) had erythema migrans and 217 (21.0%) had serologic confirmation of the diagnosis. Inapparent infection was discovered in 59 (5.4%) patients. Other Types of skin changes (II and III stage) were found in 123 (11.9%) patients. The disease resulted in neurologic, joint and cardiac manifestations in somewhat lower percentage of patients (6.3%, 6.6% and 1.5%, respectively). In the three-year period (1990-1992) microscopic examination of the ticks (Ixodes ricinus) collected at several green areas of Belgrade confirmed the presence of B. burgdorferi in 29.1 per cent.
Vector-Borne and Zoonotic Diseases, 2010
Lyme borreliosis is vector-borne zoonosis. The causative agent of Lyme borreliosis is a spirochet... more Lyme borreliosis is vector-borne zoonosis. The causative agent of Lyme borreliosis is a spirochete of Borrelia burgdorferi (Bb) sensu lato complex, which is transmitted by ticks of the Ixodes ricinus complex. The aim of our paper is to estimate the prevalence of I. ricinus ticks, the level of their infectivity by Bb, and the prevalence of certain genospecies of Bb sensu lato in ixodide ticks inhabiting Belgrade. An estimate of the tick population density was expressed by the value of flag/hour. For isolation and cultivation of Borrelia, selective Barbour-Stonner-Kelly II media was used. Typization of Borrelia was made by applying the species-specific polymerase chain reaction (PCR) and polymerase chain reaction-restriction fragment length polymorphism analysis. In statistical analysis, Chi(2) test was used. Values of flag/hour have varied in relation to year observed and type of habitat: The lowest values were recorded in the city parks (17.9). The values were higher in parks-woods (19.7 and 33.4, respectively). The highest values were detected in localities similar to wooded areas (48.0). The estimated average infestation of ticks with Bb was 21.9%, excluding statistically significant differences by years of investigation. We found the dominance of Borrelia afzelii (75%). Bb sensu stricto (22.2%) as well as Borrelia garinii (2.8%) was much less present. Statistically significant difference was established in the prevalence of the above-mentioned genospecies in relation to the examined localities. We have established the prevalence of all three genospecies in the city of Belgrade. Bb sensu lato was found, with the dominance of B. afzelii.
PubMed, 1993
Our prospective study covered 1093 patients with epidemiological features and demonstrable clinic... more Our prospective study covered 1093 patients with epidemiological features and demonstrable clinical manifestations of Lyme borreliosis from 1987 to 1992. Basic criteria for the inclusion of our patients in the study were: tick bite, erythema migrans and antibodies to B. burgdorferi in each patient's serum. Various clinical manifestations were found un 1034 (94.6%) patients out of whom 829 (80.2%) had a history of tick bite, 901 (87.1%) had erythema migrans and 217 (21.0%) had serologic confirmation of the diagnosis. Inapparent infection was discovered in 59 (5.4%) patients. Other Types of skin changes (II and III stage) were found in 123 (11.9%) patients. The disease resulted in neurologic, joint and cardiac manifestations in somewhat lower percentage of patients (6.3%, 6.6% and 1.5%, respectively). In the three-year period (1990-1992) microscopic examination of the ticks (Ixodes ricinus) collected at several green areas of Belgrade confirmed the presence of B. burgdorferi in 29.1 per cent.
Vaccines
The epidemic control approach was based on non-pharmacological measures in the first year of the ... more The epidemic control approach was based on non-pharmacological measures in the first year of the COVID-19 pandemic, followed by vaccine uptake in the second year. Vaccine uptake depends on the individual attitude toward vaccination. The aim was to assess the changes in attitudes regarding COVID-19 vaccine protection during the pandemic and to determine the vaccination uptake concerning these attitudes. A panel study on COVID-19 vaccine attitudes and vaccination against COVID-19 was conducted in Belgrade, Serbia. The first survey was carried out in May–June 2020, and the second survey was organized in August–September 2021. During the baseline testing performed in 2020, 64.4% of respondents believed that the future vaccine against COVID-19 could protect against the COVID-19 disease, while 9.7% thought that it could not, and 25.9% were unsure. One year later, in the second survey, the percentage of participants with positive attitudes was slightly lower (64.7% vs. 62.5%). However, neg...
Vojnosanitetski Pregled, 2018
Background/Aim. Cervical cancer is still an important public health problem in Belgrade. The aim ... more Background/Aim. Cervical cancer is still an important public health problem in Belgrade. The aim of this study was to explore spatial patterns of cervical cancer, provision and accessibility of women's health service on the primary health care level in Belgrade, as well as the needs for improving cancer surveillance and preventive programs. Methods. This study applied a descriptive epidemiological method and a geographic information system based on data on cervical cancer diagnosed among female residents of Belgrade in 2006 and 2011. A map of the density of cases, with precise and complete data on the address of residence at the time of diagnosis, and a map of the distribution of gynecological practices in the primary health care in Belgrade, were generated through the process of georeferencing. Results. A total of 569 cases of cervical cancer were registered in 2006 and 2011, without significant differences. Significant associations were noticed for municipality of residence and year of diagnosis (χ 2 = 42.99, df = 16, p = 0.000), and year of diagnosis and age groups 30-34 (р = 0.038, f = 3.998, df = 11, ANOVA), 40-44 (р = 0.001, f = 7.545 df = 13, ANOVA) and 45-49 (р = 0.046, f = 2.679, df = 15, ANOVA). The process of georeferencing covered a total of 466 (81.8%) cases with 97.4% of all cases diagnosed in 2006 and 68.6% in 2011. The generated maps showed similar spatial patterns of cases for both years: a higher density of cases with addresses in central parts of urban and suburban municipalities, as well as in parts of densely populated areas of urban municipalities. There was no regularity of grouping found for the cases in relation to the provision of women's health service, or of distance from the place of residence of cases to gynecological practices. Conclusion. Our results indicate possibilities for the perception of the spatial distribution of cervical cancer and needs for improving cancer surveillance and preventive programs on small geographical areas.
Medicinski podmladak, 2014
Medicinski podmladak, 2014
Vector borne and zoonotic diseases (Larchmont, N.Y.)
Lyme borreliosis is vector-borne zoonosis. The causative agent of Lyme borreliosis is a spirochet... more Lyme borreliosis is vector-borne zoonosis. The causative agent of Lyme borreliosis is a spirochete of Borrelia burgdorferi (Bb) sensu lato complex, which is transmitted by ticks of the Ixodes ricinus complex. The aim of our paper is to estimate the prevalence of I. ricinus ticks, the level of their infectivity by Bb, and the prevalence of certain genospecies of Bb sensu lato in ixodide ticks inhabiting Belgrade. An estimate of the tick population density was expressed by the value of flag/hour. For isolation and cultivation of Borrelia, selective Barbour-Stonner-Kelly II media was used. Typization of Borrelia was made by applying the species-specific polymerase chain reaction (PCR) and polymerase chain reaction-restriction fragment length polymorphism analysis. In statistical analysis, Chi(2) test was used. Values of flag/hour have varied in relation to year observed and type of habitat: The lowest values were recorded in the city parks (17.9). The values were higher in parks-woods ...
Vojnosanitetski pregled
Background/Aim. Cervical cancer is still an important public health problem in Belgrade. The aim ... more Background/Aim. Cervical cancer is still an important public health problem in Belgrade. The aim of this study was to explore spatial patterns of cervical cancer, provision and accessibility of women?s health service on the primary health care level in Belgrade, as well as the needs for improving cancer surveillance and preventive programs. Methods. This study applied a descriptive epidemiological method and a geographic information system based on data on cervical cancer diagnosed among female residents of Belgrade in 2006 and 2011. A map of the density of cases, with precise and complete data on the address of residence at the time of diagnosis, and a map of the distribution of gynecological practices in the primary health care in Belgrade, were generated through the process of georeferencing. Results. A total of 569 cases of cervical cancer were registered in 2006 and 2011, without significant differences. Significant associations were noticed for municipality of residence and ye...
Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, 2017
Aim To investigate a correlation between cervical canal infection and imminent preterm labor and ... more Aim To investigate a correlation between cervical canal infection and imminent preterm labor and to identify most frequent pathogens. Methods A prospective study was conducted in obstetrics/gynecology departments of Health Center and the University Clinical Center Tuzla, and General Hospital Tešanj (Bosnia and Herzegovina, B&H) between October 2013 and May 2014. An examined group included 50 healthy pregnant women with singleton pregnancy of the gestation age between the 28th and 37th week, with cervical changes that are related to imminent preterm labor. Changes were detected by ultrasound biometry of cervix and modified Bishop score. A control group included 30 healthy pregnant women with singleton pregnancy of the gestation age between the 28th and 37th week of pregnancy without signs of imminent preterm labor. Cervical mucus was microbiologically analyzed for identification of pathogens. Results The infection in cervical canal was proven in 35 (70%) examinees and four (13%) pati...
Vojnosanitetski pregled, 2015
Background/Aim. Norovirus (NoV), formerly Norwalk-like virus is the most common cause of acute ga... more Background/Aim. Norovirus (NoV), formerly Norwalk-like virus is the most common cause of acute gastroenteritis in humans of all ages. It is known that 90% of viral gastroenteritis and about 60-85% of all outbreaks of gastroenteritis, especially in the territory of United States of America, Europe and Japan are caused by this virus. For the countries of the northern hemisphere, individual cases and outbreaks of acute NoV gastroenteritis appear in seasonal pattern, mainly during the winter months. The aim of this study was to describe characteristics of acute gastroenteritis with the established NoV etiology in Serbia. Methods. The study group included 88 patients with the symptoms of acute gastroenteritis, throughout the year 2010 and 2011. From all the patients, stool samples were taken less than three days from the onset of symptoms. Detection of NoV in stool samples was performed by commercial qualitative immunochromatography assay. Statistical analysis included application of χ 2 test, Mann-Whitney U-test, Kruskal-Wallis's test, Spearman's rank correlation test and logistic regression analysis. Results. Outbreaks of acute gastroenteritis caused by NoV were recorded to be the most common in children with the incidence of infection of 50% in the age group 0-15 years. Analysis of individual symptoms in the NoV proven infection, showed that diarrhea was the most common symptom, followed by vomiting especially in small children, while abdominal pain was most common in elderly (≥ 65 years). The presence of frequent vomiting, more than 4 times/day, indicated NoV infection in the women, while for men the infection was always presented with diarrhea. Conclusion. The obtained results confirmed that small children and elderly are the most susceptible to NoV infection and that outbreaks are more frequent in the winter months. Those who consumed food in restaurants and other public facilities were not at higher risk for NoV infection.
Vector-Borne and Zoonotic Diseases, 2010
Lyme borreliosis is vector-borne zoonosis. The causative agent of Lyme borreliosis is a spirochet... more Lyme borreliosis is vector-borne zoonosis. The causative agent of Lyme borreliosis is a spirochete of Borrelia burgdorferi (Bb) sensu lato complex, which is transmitted by ticks of the Ixodes ricinus complex. The aim of our paper is to estimate the prevalence of I. ricinus ticks, the level of their infectivity by Bb, and the prevalence of certain genospecies of Bb sensu lato in ixodide ticks inhabiting Belgrade. An estimate of the tick population density was expressed by the value of flag/hour. For isolation and cultivation of Borrelia, selective Barbour-Stonner-Kelly II media was used. Typization of Borrelia was made by applying the species-specific polymerase chain reaction (PCR) and polymerase chain reaction-restriction fragment length polymorphism analysis. In statistical analysis, Chi(2) test was used. Values of flag/hour have varied in relation to year observed and type of habitat: The lowest values were recorded in the city parks (17.9). The values were higher in parks-woods (19.7 and 33.4, respectively). The highest values were detected in localities similar to wooded areas (48.0). The estimated average infestation of ticks with Bb was 21.9%, excluding statistically significant differences by years of investigation. We found the dominance of Borrelia afzelii (75%). Bb sensu stricto (22.2%) as well as Borrelia garinii (2.8%) was much less present. Statistically significant difference was established in the prevalence of the above-mentioned genospecies in relation to the examined localities. We have established the prevalence of all three genospecies in the city of Belgrade. Bb sensu lato was found, with the dominance of B. afzelii.
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Papers by Nevenka Pavlovic