Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2014
Extraction of bioactive materials from herbal plants may be interesting due to the growing trend ... more Extraction of bioactive materials from herbal plants may be interesting due to the growing trend of using herbal remedies instead of chemical ones. The aim of present study is to optimize the conditions of Berberine extraction from roots of <em>Berberis Vulgaris</em> by supercritical CO<sub>2</sub>. The dependency of Berberine extraction yield on extraction parameters, time and pressure, was studied by Response surface Methodology. The effective factors on the extraction yield and adequacy of proposed model was investigated according to the experimental data and statistical analysis. The correlation coefficient (R<sup>2</sup> = 92.71 %( showed that about 93% of all alternatives can be explained by this experimental model. Pressure has the most influence on yield of extracted berberine and the interaction term of Time –Pressure is statistically significant on the berberine yield. Using supercritical CO<sub>2</sub> method with pressure i...
Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2014
Extraction of bioactive materials from herbal plants may be interesting due to the growing trend ... more Extraction of bioactive materials from herbal plants may be interesting due to the growing trend of using herbal remedies instead of chemical ones. The aim of present study is to optimize the conditions of Berberine extraction from roots of <em>Berberis Vulgaris</em> by supercritical CO<sub>2</sub>. The dependency of Berberine extraction yield on extraction parameters, time and pressure, was studied by Response surface Methodology. The effective factors on the extraction yield and adequacy of proposed model was investigated according to the experimental data and statistical analysis. The correlation coefficient (R<sup>2</sup> = 92.71 %( showed that about 93% of all alternatives can be explained by this experimental model. Pressure has the most influence on yield of extracted berberine and the interaction term of Time –Pressure is statistically significant on the berberine yield. Using supercritical CO<sub>2</sub> method with pressure i...
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