Papers by Mohamed FATH ELBAB
Journal of Taibah University for Science, 2016
The aim was to study the influence of albumin supplementation on the changes of the kidney functi... more The aim was to study the influence of albumin supplementation on the changes of the kidney function and structure in cirrhotic rats induced by common bile duct ligation (BDL). Twenty-four male albino rats weighing 200-250 g were divided into Group I: 6 rats underwent laparotomy alone, and the bile duct was only dissected from the surrounding tissue; Group II: 6 rats underwent a sham operation and received 2% albumin in their drinking water; Group III: 6 rats were subjected to bile duct ligation only; and Group IV: 6 rats were subjected to bile duct ligation and received a daily albumin 2% in drinking water. All rats were sacrificed after 4 weeks. We measured the liver and kidney functions and oxidative stress markers in the renal tissue and conducted a histological evaluation of the liver and kidney. The liver enzymes were decreased, but there was no significant difference in the bilirubin levels in group IV compared to group III. There was a significant elevation of serum creatinine in group III compared to group II, and serum creatinine was attenuated in group IV. The renal tissue catalase activity and reduced glutathione, as well as the nitric oxide levels, were significantly increased in group IV and were elevated in group III. Histologically, the livers of group IV showed degeneration and inflammatory cell infiltration with regeneration areas in which normal hepatocytes appeared. The kidneys of group IV showed recovery as well as areas of inflammatory cell infiltration. Some tubules appeared with normal epithelial lining. In conclusion, the results suggest that albumin partially improves the renal functions and structures after their disturbances as a result of BDL.
research Square, 2022
Abstract
Background: The spread of misinformation about different health issues, has become a gro... more Abstract
Background: The spread of misinformation about different health issues, has become a growing threat nowadays. The process of identifying credible information became a real problem of high urgency. It took a new dimension with the creation of numerous web platforms and ubiquity of internet coverage. During the current pandemic of COVID-19, misinformation is not the only challenge, but infodemic is another serious consequence of the growing digitization. Infodemic is defined as an excessive amount of information about a problem that is typically unreliable, false or misleading, spreads rapidly, and makes a solution more difficult to achieve. This causes anxiety and mistrust in health authorities, leading to decrease capacities for decision-making and undermining public responses, especially during disease outbreaks or pandemics.
Aim: The current study was designed to evaluate the effect of implementing a digital intervention training module, to educate participants about choosing credible online health information, according to quality standards and protocols.
Methods: This is a quasi-experimental study with pre/post-assessment comparisons. It took place between October 2019 and October 2020 with the recruitment of a group of 480 medical students, from 1st , 2nd and 3rd academic years, at the Faculty of Medicine. They were assigned to an intervention and a control group. The intervention group attended the digital health module, which was conducted online with both its theoretical and practical components. Participants responded to pre and post online questionnaire through google forms, in addition to a post-intervention assessment.
Results: Results showed post-assessment significant improvements in all items related to seeking online health information and the ability to check the credibility of such information, among the intervention group in comparison to the control group with p-value< 0.05.
Conclusion: The infodemic caused by COVID- 19 pandemic, with all its associated psychological pressure and panic due to misinformation, made it really crucial to disseminate awareness about credible digital information sources. Targeted digital health interventions about online health information quality and credibility, are highly promising, due to the safe outreach and accessibility without any physical contacting, especially during the pandemic time.
Alexandria Journal of Medicine, 2022
Achieving high levels of integration in the basic medical sciences' curricula is challenging. Pro... more Achieving high levels of integration in the basic medical sciences' curricula is challenging. Project-based learning (PtBL) is an inquiry-based learning approach that can be used in multiple educational contexts with various designs. We used PtBL to enhance curricular integration during the pre-clerkship years. The study was done at The Faculty of Medicine, Helwan University, Cairo, Egypt. We designed interdisciplinary clinically relevant integrated research project tasks. Tasks followed curricular objectives. Students worked in teams to write and deliver project reports. Based on their understanding of the basic medical sciences, they analyzed the assigned tasks and used reasoning to create diagnoses. They related the condition to the disrupted normal structure/functions, suggested/contraindicated specific treatment and preventive plans. A cross-sectional survey was introduced to assess students' perceptions of the learning approach used. Response rate was 52% (n = 694). Students' responses were analyzed. Most students (84.6%) were satisfied by the integrated interdisciplinary PtBL. They (57.9%) preferred substituting the traditional lectures completely by it. Students understood the relation between objectives of disciplines after PtBL completion (mean 3.66, SD ±0.92) higher than before it (mean 3.46, SD ±0.91), (P = 0.000). Students' ranking for the degree of integration between basic/clinical sciences in the PtBL was significantly associated with the developed clinical reasoning rank (P = 0.000). It was also associated with responses supporting the future implementation of the PtBL again (P = 0.002). Various ways of adding PtBL approach to the curricula were suggested. The PtBL can be used as a complementary learning method to elevate the level of integration within a multidisciplinary approach to boost students' learning.
Objective: To investigate the effects of green tea extract (GTE) in the presence or absence of gl... more Objective: To investigate the effects of green tea extract (GTE) in the presence or absence of glibenclamide on blood glucose level, haemoglobin, glycosylated haemoglobin, activities of some liver enzymes (hexokinase and glucose-6phosphatase), serum lipid profile and plasma insulin in normal and Streptozotocin (STZ) diabetic rats. Design: Male Sprague-Dawley rats were used and diabetes was induced in overnight fasted rats using STZ (45 mg/Kg, i.p.). The diabetic rat was given orally GTE (500 mg/Kg) alone or glibenclamide (0.5 mg/Kg) alone or in combination with glibenclamide (250 mg/Kg + 0.25 mg/Kg) for 30 days.
Journal of Taibah University Medical Sciences, 2011
Objectives Diabetes mellitus (DM) is a major public health problem worldwide. The aim is to asses... more Objectives Diabetes mellitus (DM) is a major public health problem worldwide. The aim is to assess the early detection of impaired nerve function and the risk factors associated with the development of diabetic neuropathy. Methods It is a prospective descriptive study of age-matched 263 diabetic Saudi patients from the outpatient clinic of the Diabetic Centre in King Fahd Hospital in Almadinah Almunawwarah in Kingdom of Saudi Arabia during 2008-2009. Written informed consent was obtained from each subject after the protocol was approved by the local ethics committee. All subjects were diagnosed as diabetics using WHO criteria. We obtained detailed demographic data as age, sex, special habits, height, weight and body mass index, arterial blood pressure, type and duration of diabetes, glycosated haemoglobin (HbA1C), lipid profile, management, family history of hypertension, diabetes. Assessment of neuropathy by using the Diabetic neuropathy index and diabetic neuropathy score. Asymptomatic patients who scored less than two in clinical examination were referred to be assessed by complete neurological examination, and nerve conduction studies. Data were calculated and compared by using SPSS version 13.0. Results The type I were 39 (14.8%) and type II were 244 (85.2%) diabetic patients and the mean duration of diabetes mellitus in all diabetic patients was 13.89 ± 8.7 years. The symptomatic diabetic neuropathy patients were 165 (62.7%) out of 263 diabetic patients and the asymptomatic were 98 (37.3%). The risk factors for neuropathy were old age, poor blood sugar control, long duration of diabetes, hyperlepidemia, Body Mass Index (BMI). There were no statistical significant differences in relation to types of diabetes mellitus. There was positive correlation which shown by the linear regression charts between the grades of nerve conduction defects in asymptomatic diabetic neuropathy patients and duration of diabetes, age, BMI and HbA1C. Conclusion The early detection of by sub-clinical nerve conduction of diabetic patients is of a major clinical interest that could lead to more intensive supervision of diabetic patients. Further studies should be performed in order to confirm these findings.
International Journal of General Medicine, 2013
Type 2 diabetes is a metabolic disease associated with serious complications, including diabetic ... more Type 2 diabetes is a metabolic disease associated with serious complications, including diabetic retinopathy (DR). The authors' main aim was to investigate biochemical parameters and the oxidative stress associated with the type 2 DR patients and to study gene expression of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) among patients with DR [DR(+)] compared with a control nondiabetic group. In all, 67 patients with DR included in this study were diabetic for more than 10 years. Among them, 22 patients were DR(+), and 45 patients did not have DR [DR(-)]. The subjects' age range was 14 years to 80 years old with diabetes duration range between 2 and 45 years. Body mass index (BMI) was 31.43
lit.az
... Sherif Reffat1, Bassem Sheikh2, Mohamed Fath-EL-Bab3, Abdelwahab M. Gabal4, Magdi Ibrahim5, A... more ... Sherif Reffat1, Bassem Sheikh2, Mohamed Fath-EL-Bab3, Abdelwahab M. Gabal4, Magdi Ibrahim5, Amany Hassan6 and Hassan Sandgji5 ... While Al-Rajeh used carotid bruit 2, we used the carotid duplex and ABIP as an indication for vascular pathology in these patients, which ...
Medical Teacher, 2013
We reassessed the perception of all undergraduate students in Taibah medical college regarding th... more We reassessed the perception of all undergraduate students in Taibah medical college regarding the educational environment during the academic year 2010-2011 and compared it with the assessment carried out three years earlier in order to identify the change over time from previous assessment. In the present prospective study, the validated 50-item Dundee Ready Education Environment Measure (DREEM) inventory was collected from medical students of basic phase (n = 302) and clinical phase (n = 222) and compared the scores of students&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; responses with those of previous assessment 3 years earlier. In the year 2007/2008 DREEM inventory scored 109.1/200 and scored 120.70/200 (p ≤ 0.0001) in the year 2010/2011. There was an interesting inclination of female students towards a more positively perceived learning environment as compared to male students (26/48 versus 24/48, p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.03). There were statistically significant differences in all domain components of DREEM between the academic years 2007/2008 and 2010/2011. DREEM helped pinpoint areas of change in students&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; perception regarding many aspects of the educational environment. It also helped to identify areas that are still in need of improvement by the college&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s administration and staff. DREEM inventory can be used to monitor change over time in the educational environment.
Journal of Taibah University Medical Sciences, 2011
Diabetes mellitus (DM) is a major public health problem worldwide. The aim is to assess the early... more Diabetes mellitus (DM) is a major public health problem worldwide. The aim is to assess the early detection of impaired nerve function and the risk factors associated with the development of diabetic neuropathy.
Stroke is a major community problem with a high incidence and major neurological disability. Amon... more Stroke is a major community problem with a high incidence and major neurological disability. Among the related risk factors, metabolic syndrome is gaining concern. Its relation to stroke was suggested. We measured its prevalence among acute stroke patients in this study. Between October 2009 and May 2010, patients admitted to King Fahad Hospital, AL-Madinah AL-Munawarah, Kingdom of Saudi Arabia, with acute stroke were recruited to this study. Demographic and clinical data, results of investigations, final diagnosis, the Ankle/Brachial Index Pressure and waist circumference were collected. Patients were considered positive for metabolic syndrome when had ≥3 of the components according to the Adult Treatment Panel III. Correlation between metabolic syndrome state and different clinical variables were measured. 60 patients were recruited in the study. The metabolic syndrome prevalence was 57% among the entire population and 64% among the ischemic strokes. The most prevalent metabolic syndrome component was hypertension followed by diabetes. C-reactive protein was high among the different studied subgroups. Finally platelet count was within the normal range but lower among metabolic syndrome positive patients. The percentages of metabolic syndrome positive patients were significantly higher among ischemic stroke patients and in those with extracranial carotid atherosclerotic lesions.
Uploads
Papers by Mohamed FATH ELBAB
Background: The spread of misinformation about different health issues, has become a growing threat nowadays. The process of identifying credible information became a real problem of high urgency. It took a new dimension with the creation of numerous web platforms and ubiquity of internet coverage. During the current pandemic of COVID-19, misinformation is not the only challenge, but infodemic is another serious consequence of the growing digitization. Infodemic is defined as an excessive amount of information about a problem that is typically unreliable, false or misleading, spreads rapidly, and makes a solution more difficult to achieve. This causes anxiety and mistrust in health authorities, leading to decrease capacities for decision-making and undermining public responses, especially during disease outbreaks or pandemics.
Aim: The current study was designed to evaluate the effect of implementing a digital intervention training module, to educate participants about choosing credible online health information, according to quality standards and protocols.
Methods: This is a quasi-experimental study with pre/post-assessment comparisons. It took place between October 2019 and October 2020 with the recruitment of a group of 480 medical students, from 1st , 2nd and 3rd academic years, at the Faculty of Medicine. They were assigned to an intervention and a control group. The intervention group attended the digital health module, which was conducted online with both its theoretical and practical components. Participants responded to pre and post online questionnaire through google forms, in addition to a post-intervention assessment.
Results: Results showed post-assessment significant improvements in all items related to seeking online health information and the ability to check the credibility of such information, among the intervention group in comparison to the control group with p-value< 0.05.
Conclusion: The infodemic caused by COVID- 19 pandemic, with all its associated psychological pressure and panic due to misinformation, made it really crucial to disseminate awareness about credible digital information sources. Targeted digital health interventions about online health information quality and credibility, are highly promising, due to the safe outreach and accessibility without any physical contacting, especially during the pandemic time.
Background: The spread of misinformation about different health issues, has become a growing threat nowadays. The process of identifying credible information became a real problem of high urgency. It took a new dimension with the creation of numerous web platforms and ubiquity of internet coverage. During the current pandemic of COVID-19, misinformation is not the only challenge, but infodemic is another serious consequence of the growing digitization. Infodemic is defined as an excessive amount of information about a problem that is typically unreliable, false or misleading, spreads rapidly, and makes a solution more difficult to achieve. This causes anxiety and mistrust in health authorities, leading to decrease capacities for decision-making and undermining public responses, especially during disease outbreaks or pandemics.
Aim: The current study was designed to evaluate the effect of implementing a digital intervention training module, to educate participants about choosing credible online health information, according to quality standards and protocols.
Methods: This is a quasi-experimental study with pre/post-assessment comparisons. It took place between October 2019 and October 2020 with the recruitment of a group of 480 medical students, from 1st , 2nd and 3rd academic years, at the Faculty of Medicine. They were assigned to an intervention and a control group. The intervention group attended the digital health module, which was conducted online with both its theoretical and practical components. Participants responded to pre and post online questionnaire through google forms, in addition to a post-intervention assessment.
Results: Results showed post-assessment significant improvements in all items related to seeking online health information and the ability to check the credibility of such information, among the intervention group in comparison to the control group with p-value< 0.05.
Conclusion: The infodemic caused by COVID- 19 pandemic, with all its associated psychological pressure and panic due to misinformation, made it really crucial to disseminate awareness about credible digital information sources. Targeted digital health interventions about online health information quality and credibility, are highly promising, due to the safe outreach and accessibility without any physical contacting, especially during the pandemic time.