Papers by Manvendra Singh
Journal of Pharmacognosy and Phytochemistry, 2017
Stevia rebaudiana is a perennial herb belonging to Asteraceae family and an excellent substitute ... more Stevia rebaudiana is a perennial herb belonging to Asteraceae family and an excellent substitute of artificial sugar. Increasing demand of quality panting material has emphasized the need of rapid and mass multiplication through plant tissue culture technology in limited time duration. Sterilized in vivo leaves were used as leaf explants on different concentration of BAP, Kin and TDZ. In all media, shoot induction was not observed at any concentration from in vivo leaf explants. Cold treatment (4 oC) of different time duration (0-72 hr) was applied on in vitro leaf explants and cultured on various concentration of TDZ (1.0-5.0 mg/l). Highest shoot induction response (42.40%) was occurred at 4.0 mg/l TDZ from 72 hrs cold treated in vitro leaf. Highest number of shoots per explant (25.80) was observed at 3.0 mg/l TDZ from 48 hrs cold treated in vitro leaf explants. Highest shoot length (1.36 cm) was observed at 3.0 mg/l TDZ from 72 hrs cold treated in vitro leaf. Cold treatment was us...
Evolutionary changes in the anatomy and physiology of the female reproductive system underlie the... more Evolutionary changes in the anatomy and physiology of the female reproductive system underlie the origins and diversification of pregnancy in Eutherian (“Placental”) mammals. This developmental and evolutionary history constrains normal physiological functions and biases the ways in which dysfunction contributes to reproductive trait diseases and adverse pregnancy outcomes. Here, we show that gene expression changes in the human endometrium during pregnancy are associated with the evolution of human-specific traits and pathologies of pregnancy. We found that hundreds of genes gained or lost endometrial expression in the human lineage. Among these are genes that may contribute to human-specific maternal-fetal communication (HTR2B) and maternal-fetal immunotolerance (PDCD1LG2) systems, as well as vascular remodeling and deep placental invasion (CORIN). These data suggest that explicit evolutionary studies of anatomical systems complement traditional methods for characterizing the gene...
RSC Advances, 2018
In hepatocellular carcinoma (HCC), primary liver cancer is primarily responsible for inflammation... more In hepatocellular carcinoma (HCC), primary liver cancer is primarily responsible for inflammation-related cancer as more than 90% of HCCs emerge with regard to hepatic damage and inflammation.
Uploads
Papers by Manvendra Singh