Papers by José Fernando Vera
This is the First de novo-National Clinical practice Guideline of diarrhea, 2013
Revista Gastrohnup …, 2006
The presence of blood in the vomit and feces is an emergency in pediatric age and it isn't must b... more The presence of blood in the vomit and feces is an emergency in pediatric age and it isn't must be ignored; it will cause anguish in parents and patients and always will generate a consultation immediate. In children the hemorrhage of digestive routes is a given urgency its total circulatory volume.
Revista Colombiana de Gastroenterología, Dec 30, 2019
Autoimmune hepatitis (AIH) is a progressive inflammatory liver disease. It is uncommon in childre... more Autoimmune hepatitis (AIH) is a progressive inflammatory liver disease. It is uncommon in children and adolescents, and is a diagnostic challenge for clinicians and pathologists. We describe the clinical, biochemical and histopathological characteristics of 21 pediatric patients with AIH diagnosed in the last 14 years. Liver biopsies were reassessed to analyze histopathological findings in detail. Of the 21 cases evaluated, 12 (57.1%) were girls and young women, the median age was 14 years old, and 17 (80.9%) had type 1 AIH. The most frequent clinical signs were jaundice (66.7%), choluria (44.4%), evidence of portal hypertension with esophageal varices (47.1%), and splenomegaly (41.2%). Histories of other autoimmune diseases were found in 11.8% of these patients. Elevated levels of aminotransferases were found in 89.5% of the patients, hyperbilirubinemia was found in 88.9%, and 60.0% of the cases had low levels of serum albumin. Reassessed biopsies showed portal lymphoplasmocytic infiltrate (94.4%), interface hepatitis (77.8%) and rosette formation (50.0%). Hyaline inclusions were found in Kupffer cells in 42.9% of the biopsies. About 33.5% of the cases showed cirrhosis at the initial biopsy. Despite immunosuppressive treatment, four patients required liver transplantation and two are on the waiting list. AIH in children can manifest with jaundice, choluria, signs of portal hypertension, elevated aminotransferases, hyperbilirubinemia and circulating antibodies. Hyaline inclusions in Kupffer cells may be a useful finding in the histopathological diagnosis of AIH in children.
Pediatría, 2015
As part of the Ministry of Health national Clinical Practice Guidelines (CPG) project, under the ... more As part of the Ministry of Health national Clinical Practice Guidelines (CPG) project, under the administrative and financial coordination of the of the Administrative Department of Science, Technology and Innovation (Colciencias), the Development Group has prepared a CPG based on the evidence gathered in the most recent literature. The quality of the evidence was then evaluated, along with an analysis of its characteristics, in order to improve the recommendations for the Colombian context. GRADE methodology was used to evaluate the risks and biases according to the prioritised outcomes and to develop these recommendations in order to provide the answers to the questions that were pre-established and discussed with the funding body. The members of the group were professionals from all areas involved in diarrhoea in children. It also included patient representatives also took part, and values and preferences of the parents were taken into account. A summary is presented on the recommendations for the diagnosis and treatment of children with diarrhoea in Colombia.
Nota legal : En todos los casos en los que esta GAI-SCA sea utilizada para la gestión de las orga... more Nota legal : En todos los casos en los que esta GAI-SCA sea utilizada para la gestión de las organizaciones del sector salud en Colombia,
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Papers by José Fernando Vera