The purpose of this research is to know how much influence of Return on Assets (ROA) and Dividend... more The purpose of this research is to know how much influence of Return on Assets (ROA) and Dividend Policy to Firm Value partially on Manufacturing Companies. The method of data collection is through the population data of manufacturing companies for the period 2017 to 2021. The data is taken through the official website of the Indonesia Stock Exchange (www.idx.co.id). The total population was found to be 167 listed companies. The samples of companies used in this study are twenty seven companies that have passed the criteria that have been determined in purposive sampling. In this study, the data used is secondary data. To obtain secondary data, it is taken from financial reports, annual reports and sustainability reports of each manufacturing company listed on the Indonesia Stock Exchange. Data processing using IBM SPSS 25 application.
ABSTRACT Colorectal cancer is a rare yet aggressive neoplasm in young adult. This cancer was asso... more ABSTRACT Colorectal cancer is a rare yet aggressive neoplasm in young adult. This cancer was associated with several bacterial and viral infections like Streptococcus bovis, Helicobacter pylori, human papilloma virus, and Clostridium septicum. Here we report a case of Clostridium difficile and Entamoeba histolytica infection in young adult male patient with colorectal cancer. The patient presented with chronic bloody diarrhea since one year prior to diagnosis with histories of antibiotics but no hospitalization, surgery or chemotherapy
ABSTRACT: THE CORRELATION OF KNOWLEDGE AND FAMILY SUPPORT WITH SPUTUM EXAMINATION IN PATIENTS WIT... more ABSTRACT: THE CORRELATION OF KNOWLEDGE AND FAMILY SUPPORT WITH SPUTUM EXAMINATION IN PATIENTS WITH SUSPECTED TB IN THE WORK AREA OF BRABASAN HEALTH CENTER IN MESUJI Introduction: Achievement of positive smear pulmonary TB findings in Lampung Province, which is 38%, has not reached the MSS target. Brabasan health center as many as 28 cases. As for the case of death at the Brabasan Community Health Center during 2017, there were 5 patients with pulmonary TB who died. the purpose knowing the relationship of knowledge and family support with sputum examination in patients with suspected TB in the work area of Brabasan Health Center in Mesuji Regency in 2020Method: This type of research is quantitative, analytical survey research design with cross sectional approach. The population was all patients with suspected TB as many as 332 respondents, a sample of 182 respondents was taken by proportional random sampling. Univariate (frequency distribution) and bivariate data analysis used the c...
Prevalensi kematian akibat kardiovaskuler pada pasien penyakit ginjal kronik stadium akhir yang m... more Prevalensi kematian akibat kardiovaskuler pada pasien penyakit ginjal kronik stadium akhir yang menjalani hemodialisis, baik di negara maju maupun berkembang masih tinggi. Penelitian berbasis populasi menilai efektivitas berbagai terapi untuk mengurangi faktor risiko kematian kardiovaskuler di populasi ini telah dilakukan, salah satunya adalah suplementasi vitamin C, yang merupakan sebuah suplemen kecil, tidak mahal, dan mudah didapat. Namun, pada praktik klinis masih ditemukan kontroversi seputar risiko dan manfaat suplemen ini.
The web-based New Employee Recruitment and Placement Application could be used as a solution to h... more The web-based New Employee Recruitment and Placement Application could be used as a solution to handle recruitment process in company. This application could control recruitment process from request new employee phase, selection phase until placement for hired employee. The other hand this application could help to process relevant recruitment report with data integration system. In this study, author discusses how to build the web-base New Employee Recruitment and Placement Application in PT BFI Finance Indonesia, Tbk with system analytic methodology used is S.W.O.T and and system development methodology is RAD which includes stages of requirement planning, system design and implementation. The result of this study is system the web-based new employee recruitment and placement application sytem to help company to control recruitment process from branch offices and HC Regional offices and to help employee candidates in registration vacancy process
-The use of interactive CD-based learning adobe director as the introduction of additional rarely... more -The use of interactive CD-based learning adobe director as the introduction of additional rarely used. Because The teachers are accustomed to using books in the learning process in the classroom. the authors conducted a study to see whether the media for computer-based learning to helps students SMK N 2 Pariaman X class multimedia in understanding Multimedia subjects. This research aims to develop an interactive CD as a medium of learning in Computer Assembling subjects in class X SMK N 2 Pariaman. Results of the assessment of the overall three-validator of test vote on CD-Interactive amounted to 88.67%, so the rate can be interpreted validity is valid in use. Overall assessment of the CD-Interactive practicality as a learning resource for 86.08%, so the rate can be interpreted is Very Practical in use. As well as assessing the effectiveness of the CD-Interactive as a learning resource for 85.25%, the rate of effectiveness can be interpreted Highly Effective in use .
The study describes the revitalization of institutional functions through the Saribattang Rapid R... more The study describes the revitalization of institutional functions through the Saribattang Rapid Response Team (RRT) innovation program in dealing with street children in Makassar City Indonesia. This type of research is descriptive with a qualitative approach. The data sources consist of primary data and secondary data with the research instrument being the researcher himself in conducting observations, interviews, and documentation studies. The results of the study found that there was a revitalization of institutional functions in the form of implementing the Saribattang RRT innovation which was shown through relative advantages, easy to adopt, relevant to the systems and norms adopted by the actors, and the results can be measured through the method of data recapitulation of controlling street children, direct checks in the field, and the results of home visits by social workers. The revitalization of institutional functions and the development of innovation in RRT Saribattang is...
Lymphedema (LE) is a chronic medical condition characterized by lymphatic fluid retention, result... more Lymphedema (LE) is a chronic medical condition characterized by lymphatic fluid retention, resulting in tissue swelling. There are two general classifications of LE; primary and secondary which are based on two mechanisms; lymphatic obstruction and lymphatic interruption. The most common cause of LE in the developing world is secondary to an infection known as filariasis. Cancer including Hodgkin and non-Hodgkin lymphomas; and its treatment are some causes of secondary LE. LE also could maintain the persistence of an occult localization of lymphoma. This case illustration describes a female, 57 year-old with stage II lymphedema of both legs, bilateral inguinal lymphadenopathies that were biopsied. The filarial blood examination was negative. Biopsies showed diffuse large B-cell lymphoma.
The web-based New Employee Recruitment and Placement Application could be used as a solution to h... more The web-based New Employee Recruitment and Placement Application could be used as a solution to handle recruitment process in company. This application could control recruitment process from request new employee phase, selection phase until placement for hired employee. The other hand this application could help to process relevant recruitment report with data integration system. In this study, author discusses how to build the web-base New Employee Recruitment and Placement Application in PT BFI Finance Indonesia, Tbk with system analytic methodology used is S.W.O.T and and system development methodology is RAD which includes stages of requirement planning, system design and implementation. The result of this study is system the web-based new employee recruitment and placement application sytem to help company to control recruitment process from branch offices and HC Regional offices and to help employee candidates in registration vacancy process. Keywords: Recruitment, employee re...
on data from Globocan, the International Agency for Research on Cancer (IARC), it was reported th... more on data from Globocan, the International Agency for Research on Cancer (IARC), it was reported that in 2018 there were 2,088,849 (11.6%) new cases of breast cancer. Based on these data it is also mentioned that the number of breast cancer cases in Indonesia have the highest incidence when compared with other cancer cases, contributing up to 58,256 (16.7%) new cases (Bray et al., 2018). Breast cancer cells consist of several subtypes. The most common breast cancer is luminal subtype breast cancer with an ER-positive type. Luminal A subtype breast cancer is characterized by ER+, PR-, and HER2-(Perou and Borresen-Dale, 2011; Ostad and Parsa, 2011). Luminal A subtype breast cancer consists of MCF-7, T47D, and SUM185 cell lines. MCF-7 is the most commonly used breast cancer cell line in researches because it has very
Background: The evidence of using JAK inhibitors among hospitalized patients with COVID-19 is con... more Background: The evidence of using JAK inhibitors among hospitalized patients with COVID-19 is conflicting. The systematic review and meta-analysis aimed to address the efficacy of Janus Kinase (JAK) Inhibitors in reducing risk of mortality among hospitalized patients with COVID-19. Methods: Several electronic databases, including PubMed, EuropePMC, and the Cochrane Central Register of Controlled Trials, with relevant keywords "COVID-19 ′′ AND ("JAK inhibitor" OR "Ruxolitinib" OR "Tofacitinib" OR "Fedratinib" OR "Baricitinib") AND ("Severe" OR "Mortality"), were used to perform a systematic literature search up to December 11, 2020. All studies pertinent to the predetermined eligibility criteria were included in the analysis. Our outcome of interest was all types of mortality, clinical improvement, and clinical deterioration. Dichotomous variables of our outcomes of interest were analyzed using Maentel-Haenszel formula to obtain odds ratios (ORs) and 95% confidence intervals (CI) with random-effects modeling regardless of heterogeneity. Results: Five studies with a total of 1190 patients and were included in this systematic review and meta-analysis. The use of JAK inhibitors was associated with a reduced risk of mortality (OR 0.51, 95% CI 0.28-0.93, P = 0.02; I 2 : 7.8%, P = 0.354) and clinical improvement (OR 1.76, 95% CI 1.05-2.95, P = 0.032; I 2 : 26.4%, P = 0.253). The use of JAK inhibitors was not associated with a reduced risk of clinical deterioration (OR 0.58, 95% CI 0.28-1.19, P = 0.136; I 2 : 24.1%, P = 0.267). Conclusion: The use of JAK inhibitors was significantly associated with a reduced risk of mortality, and clinical improvement in hospitalized patients with COVID-19.
VOLT : Jurnal Ilmiah Pendidikan Teknik Elektro, 2017
This study aims to create an interactive learning module that qualifies valid, practical and effe... more This study aims to create an interactive learning module that qualifies valid, practical and effective for Computer Assembling subjects in Vocational High School. This research is a Research and Development research conducted in Vocational High School class X West Sumatra. The population of this research is SMK in West Sumatra. Samples are SMKN 6 Padang SMKN 1 Painan, SMKN 2 Pulau Punjung. The results of the assessment of the three validators overall validator test assessment of the Interactive Module of 88.67% so that the level of validity can be interpreted Valid used. Overall assessment of the practicality of the Interactive Module as a learning resource of 86.08%, so the level of practicality can be interpreted Very Practical used. And the effectiveness assessment of Interactive Module as learning resource equal to 85,25%, so the level of effectivity can be interpreted Highly Effective used.
Background: In Indonesia, geriatric population in the year 2005 was 15.8 million (7.2 % populatio... more Background: In Indonesia, geriatric population in the year 2005 was 15.8 million (7.2 % population), and expected to reach 11.34% in the year 2020. There was growing evidence for poor sleep as an independent risk factor for poor physical and mental health. Geriatric population may be particularly vulnerable to effects of sleep disturbance due to significant age-related changes in both sleep and inflammatory regulationObjective: To study the epidemiological (gender, age group) and health status (co-morbidities), sleep quality according to Pittsburgh Sleep Quality Index (PSQI) and its associations in geriatric population hospitalized in General Hospital in Karawaci, Tangerang, Banten Province, Indonesia.Materials and Methods: A hospital based cross sectional study was conducted from January to June 2014. A total of 92 subjects aged 60 years and above were selected consecutively from hospitalized geriatric patients for this study. The data was analyzed by means and proportions.Results:...
The trend of traveling has increased in recent years along with the easy access to information. T... more The trend of traveling has increased in recent years along with the easy access to information. Travelers create the itinerary before they are travelling to an area. However, creating itinerary is not easy, many factors need to be considered before deciding where to go, such as the "must visited" places in that area, distance between tourist attractions to be visited within a day, preferred tourist attractions, and other information about the places. Generating the optimized distance itinerary is similar as a Traveling Salesman Problem (TSP). The purpose of this research is to study the combination of simulated annealing and Greedy algorithms to create an itinerary. The initialization process of the simulated annealing algorithm uses Greedy algorithm searching technique and then proceeded with existing optimization step in simulated annealing method. This paper proposed a method of enhanced simulated annealing algorithm and the experiment results show the enhanced simulated annealing increase the effectiveness of simulated annealing algorithm which produce the shortest distance needed to travel places around an area.
Various Candida species are harmless commensals present in the oral mucous membranes, and Candida... more Various Candida species are harmless commensals present in the oral mucous membranes, and Candida albicans (C. albicans) is the most commonly isolated species. Overgrowth of C. albicans can lead to oral fungal infections, known as oral candidiasis, with multiple local and systemic predisposing factors. Poor oral hygiene (OH) is an important local factor that may increase the risk of oral candidiasis. An immunocompromised patient, such as cancer patient undergoing chemotherapy, has an increased susceptibility to develop oral candidiasis due to an impaired or weakened immune system. The aim of this study was to evaluate C. albicans colony forming units (CFUs) and its relationship with different levels of oral hygiene in cancer patients undergoing chemotherapy. The oral rinse technique was performed to isolate C. albicans from 60 subjects and were cultured on agar plates. Subjects were divided into different groups of OH level according to OHI-S scores. C. albicans were isolated from 44 (73.3%) subjects. There is a strong positive relationship between OH status and CFU ml-1 value (r = 0.708). It showed that oral C. albicans colonization increased significantly in cancer patients undergoing chemotheray with fair and poor OH (p = 0.001). Data from this study revealed a statistically significant relationship between oral hygiene status and C. albicans colonization among cancer patient undergoing chemotherapy. More attention should be paid to oral hygiene as one of the risk factors to be taken into account in the prevention paradigm to reduce the incidence of oral candidiasis among cancer patient undergoing chemotherapy. Further studies with larger sample sizes would be beneficial with the aim of verifying the results obtained in the present study, and consider the interaction effects of other multiple risk factors on the risk of developing oral candidiasis in cancer patients.
Abstrak_Berdasarkan penelitian yang telah dilakukan di Sekolah Menengah Kejuruan Negeri 2 Padang ... more Abstrak_Berdasarkan penelitian yang telah dilakukan di Sekolah Menengah Kejuruan Negeri 2 Padang Jl. DR.Sutomo No. 5, Kel Simpang Haru, Kec. Padang Timur, Kota Padang, Sumatera Barat di kelas X Teknik Komputer dan Jaringan pada semester ganjil, waktu penelitian dilakukan pada tanggal 8 November sampai dengan 14 November 2018 tahun ajaran 2018/2019, diperoleh nilai rata-rata penilaian uji kepraktisan terhadap media mobile learning berbasis web mobile sebesar 87,67%, sehingga tingkat praktikalitasnya dapat di interprestasikan sangat praktis digunakan.. Jadi, dapat disimpulkan bahwa Media Mobile Learning Berbasis Web Mobile mata pelajaran Komputer dan Jaringan Dasar kelas X Teknik Komputer dan Jaringan SMK Negeri 2 Padang layak digunakan untuk proses pembelajaran.
Biosaintifika: Journal of Biology & Biology Education, 2017
Colorectal carcinogenesis induced by cigarette smoke requires at least 30-40 years. This long tim... more Colorectal carcinogenesis induced by cigarette smoke requires at least 30-40 years. This long time duration causes an animal research conducted becomes relevant. This research was carried out to observe colorectal carcinogenesis due to cigarette smoke exposure in Wistar Rat. The observations focused on changes in epithelial morphology and expression of APC, MSH2 and MLH1. Twenty male Wistar rats inbreed strain were randomly allocated into control group and experimental group exposure to cigarettes smoke for 14 weeks and 28 weeks sequentially. Colorectal epithelial morphology was assessed on the histopathology examination, whereas the expression of APC, MSH2 and MLH1 was assessed on aspect of immunohistochemistry. The comparative analysis between the two groups was performed using nonparametric Mann-Whitney U test. Histology of colorectal epithelium showed pattern of colitis associated cancer that was significant both in 14 weeks and 28 weeks of treatment. This research indicated negative expression of APC, MSH2 and MLH1 in the colorectal cancer that were significant at 28 weeks of exposure. This research implies that chronic exposure to cigarette smoke can induce colitis associated colorectal cancer through decreased expression of APC, MSH2 and MLH1.
ABSTRACT Background: Measuring quality of life in breast cancer patients is of importance in asse... more ABSTRACT Background: Measuring quality of life in breast cancer patients is of importance in assessing treatment outcomes. The potential psychological and physical dysfunction caused by both the diagnosis and treatments can have a deleterious impact on the quality of a woman's life. The aim of this study is to evaluate the association of quality
to review the role of ursodeoxycholic acid in acute viral hepatitis. following literature searchi... more to review the role of ursodeoxycholic acid in acute viral hepatitis. following literature searching according to the clinical question on Pubmed and Cochrane Library. After filtered with our inclusion and exclusion criteria, one meta-analysis and two randomized clinical trials are obtained. Through critical appraisal, it was concluded that the articles meet the criteria for validity and relevance. the article found that there is a positive effect of ursodeoxycholic acid on the activity of serum transaminases and cholestasis indexes. However, there is insufficient evidence to support or to refute effects of ursodeoxycholic acid on disease's course as well as the viral load. better method of clinical trials are needed to obtain a valid and applicable result for daily practice.
Penelitian ini akan menjelaskan mengenai proses suksesi pada perusahaan keluarga yang bergerak di... more Penelitian ini akan menjelaskan mengenai proses suksesi pada perusahaan keluarga yang bergerak di bidang konveyor. Tujuan penelitian adalah untuk meneliti suksesi pada perusahaan keluarga yang bergerak di bidang konveyor yang tergolong sukses dam terus bertumbuh setelah proses suksesi tersebut. Metode yang peneliti gunakan yaitu metode kualitatif dengan melakukan wawancara langsung terhadap pemilik perusahaan, observasi dan studi pustaka. Setelah mendapatkan data maka peneliti akan melakukan uji keabsahan data dengan metode triangulasi sumber. Hasil penelitian yaitu pada perencanaan suksesi proses pemilihan calon suksesor sesuai dengan kebutuhan perusahaan namun mentoring harus terus dilangsungkan karena baru berjalan dua tahun. Proses transisi pada perusahaan keluarga yang bergerak di bidang konveyor berjalan mulus karena tidak terjadi hambatan-hambatan pada proses transisi. Evaluasi paska suksesi dinilai menghasilkan performa yang efektif berdasarkan penilaian dari 3 pola yang menyebabkan suksesi menjadi tidak efektif
The purpose of this research is to know how much influence of Return on Assets (ROA) and Dividend... more The purpose of this research is to know how much influence of Return on Assets (ROA) and Dividend Policy to Firm Value partially on Manufacturing Companies. The method of data collection is through the population data of manufacturing companies for the period 2017 to 2021. The data is taken through the official website of the Indonesia Stock Exchange (www.idx.co.id). The total population was found to be 167 listed companies. The samples of companies used in this study are twenty seven companies that have passed the criteria that have been determined in purposive sampling. In this study, the data used is secondary data. To obtain secondary data, it is taken from financial reports, annual reports and sustainability reports of each manufacturing company listed on the Indonesia Stock Exchange. Data processing using IBM SPSS 25 application.
ABSTRACT Colorectal cancer is a rare yet aggressive neoplasm in young adult. This cancer was asso... more ABSTRACT Colorectal cancer is a rare yet aggressive neoplasm in young adult. This cancer was associated with several bacterial and viral infections like Streptococcus bovis, Helicobacter pylori, human papilloma virus, and Clostridium septicum. Here we report a case of Clostridium difficile and Entamoeba histolytica infection in young adult male patient with colorectal cancer. The patient presented with chronic bloody diarrhea since one year prior to diagnosis with histories of antibiotics but no hospitalization, surgery or chemotherapy
ABSTRACT: THE CORRELATION OF KNOWLEDGE AND FAMILY SUPPORT WITH SPUTUM EXAMINATION IN PATIENTS WIT... more ABSTRACT: THE CORRELATION OF KNOWLEDGE AND FAMILY SUPPORT WITH SPUTUM EXAMINATION IN PATIENTS WITH SUSPECTED TB IN THE WORK AREA OF BRABASAN HEALTH CENTER IN MESUJI Introduction: Achievement of positive smear pulmonary TB findings in Lampung Province, which is 38%, has not reached the MSS target. Brabasan health center as many as 28 cases. As for the case of death at the Brabasan Community Health Center during 2017, there were 5 patients with pulmonary TB who died. the purpose knowing the relationship of knowledge and family support with sputum examination in patients with suspected TB in the work area of Brabasan Health Center in Mesuji Regency in 2020Method: This type of research is quantitative, analytical survey research design with cross sectional approach. The population was all patients with suspected TB as many as 332 respondents, a sample of 182 respondents was taken by proportional random sampling. Univariate (frequency distribution) and bivariate data analysis used the c...
Prevalensi kematian akibat kardiovaskuler pada pasien penyakit ginjal kronik stadium akhir yang m... more Prevalensi kematian akibat kardiovaskuler pada pasien penyakit ginjal kronik stadium akhir yang menjalani hemodialisis, baik di negara maju maupun berkembang masih tinggi. Penelitian berbasis populasi menilai efektivitas berbagai terapi untuk mengurangi faktor risiko kematian kardiovaskuler di populasi ini telah dilakukan, salah satunya adalah suplementasi vitamin C, yang merupakan sebuah suplemen kecil, tidak mahal, dan mudah didapat. Namun, pada praktik klinis masih ditemukan kontroversi seputar risiko dan manfaat suplemen ini.
The web-based New Employee Recruitment and Placement Application could be used as a solution to h... more The web-based New Employee Recruitment and Placement Application could be used as a solution to handle recruitment process in company. This application could control recruitment process from request new employee phase, selection phase until placement for hired employee. The other hand this application could help to process relevant recruitment report with data integration system. In this study, author discusses how to build the web-base New Employee Recruitment and Placement Application in PT BFI Finance Indonesia, Tbk with system analytic methodology used is S.W.O.T and and system development methodology is RAD which includes stages of requirement planning, system design and implementation. The result of this study is system the web-based new employee recruitment and placement application sytem to help company to control recruitment process from branch offices and HC Regional offices and to help employee candidates in registration vacancy process
-The use of interactive CD-based learning adobe director as the introduction of additional rarely... more -The use of interactive CD-based learning adobe director as the introduction of additional rarely used. Because The teachers are accustomed to using books in the learning process in the classroom. the authors conducted a study to see whether the media for computer-based learning to helps students SMK N 2 Pariaman X class multimedia in understanding Multimedia subjects. This research aims to develop an interactive CD as a medium of learning in Computer Assembling subjects in class X SMK N 2 Pariaman. Results of the assessment of the overall three-validator of test vote on CD-Interactive amounted to 88.67%, so the rate can be interpreted validity is valid in use. Overall assessment of the CD-Interactive practicality as a learning resource for 86.08%, so the rate can be interpreted is Very Practical in use. As well as assessing the effectiveness of the CD-Interactive as a learning resource for 85.25%, the rate of effectiveness can be interpreted Highly Effective in use .
The study describes the revitalization of institutional functions through the Saribattang Rapid R... more The study describes the revitalization of institutional functions through the Saribattang Rapid Response Team (RRT) innovation program in dealing with street children in Makassar City Indonesia. This type of research is descriptive with a qualitative approach. The data sources consist of primary data and secondary data with the research instrument being the researcher himself in conducting observations, interviews, and documentation studies. The results of the study found that there was a revitalization of institutional functions in the form of implementing the Saribattang RRT innovation which was shown through relative advantages, easy to adopt, relevant to the systems and norms adopted by the actors, and the results can be measured through the method of data recapitulation of controlling street children, direct checks in the field, and the results of home visits by social workers. The revitalization of institutional functions and the development of innovation in RRT Saribattang is...
Lymphedema (LE) is a chronic medical condition characterized by lymphatic fluid retention, result... more Lymphedema (LE) is a chronic medical condition characterized by lymphatic fluid retention, resulting in tissue swelling. There are two general classifications of LE; primary and secondary which are based on two mechanisms; lymphatic obstruction and lymphatic interruption. The most common cause of LE in the developing world is secondary to an infection known as filariasis. Cancer including Hodgkin and non-Hodgkin lymphomas; and its treatment are some causes of secondary LE. LE also could maintain the persistence of an occult localization of lymphoma. This case illustration describes a female, 57 year-old with stage II lymphedema of both legs, bilateral inguinal lymphadenopathies that were biopsied. The filarial blood examination was negative. Biopsies showed diffuse large B-cell lymphoma.
The web-based New Employee Recruitment and Placement Application could be used as a solution to h... more The web-based New Employee Recruitment and Placement Application could be used as a solution to handle recruitment process in company. This application could control recruitment process from request new employee phase, selection phase until placement for hired employee. The other hand this application could help to process relevant recruitment report with data integration system. In this study, author discusses how to build the web-base New Employee Recruitment and Placement Application in PT BFI Finance Indonesia, Tbk with system analytic methodology used is S.W.O.T and and system development methodology is RAD which includes stages of requirement planning, system design and implementation. The result of this study is system the web-based new employee recruitment and placement application sytem to help company to control recruitment process from branch offices and HC Regional offices and to help employee candidates in registration vacancy process. Keywords: Recruitment, employee re...
on data from Globocan, the International Agency for Research on Cancer (IARC), it was reported th... more on data from Globocan, the International Agency for Research on Cancer (IARC), it was reported that in 2018 there were 2,088,849 (11.6%) new cases of breast cancer. Based on these data it is also mentioned that the number of breast cancer cases in Indonesia have the highest incidence when compared with other cancer cases, contributing up to 58,256 (16.7%) new cases (Bray et al., 2018). Breast cancer cells consist of several subtypes. The most common breast cancer is luminal subtype breast cancer with an ER-positive type. Luminal A subtype breast cancer is characterized by ER+, PR-, and HER2-(Perou and Borresen-Dale, 2011; Ostad and Parsa, 2011). Luminal A subtype breast cancer consists of MCF-7, T47D, and SUM185 cell lines. MCF-7 is the most commonly used breast cancer cell line in researches because it has very
Background: The evidence of using JAK inhibitors among hospitalized patients with COVID-19 is con... more Background: The evidence of using JAK inhibitors among hospitalized patients with COVID-19 is conflicting. The systematic review and meta-analysis aimed to address the efficacy of Janus Kinase (JAK) Inhibitors in reducing risk of mortality among hospitalized patients with COVID-19. Methods: Several electronic databases, including PubMed, EuropePMC, and the Cochrane Central Register of Controlled Trials, with relevant keywords "COVID-19 ′′ AND ("JAK inhibitor" OR "Ruxolitinib" OR "Tofacitinib" OR "Fedratinib" OR "Baricitinib") AND ("Severe" OR "Mortality"), were used to perform a systematic literature search up to December 11, 2020. All studies pertinent to the predetermined eligibility criteria were included in the analysis. Our outcome of interest was all types of mortality, clinical improvement, and clinical deterioration. Dichotomous variables of our outcomes of interest were analyzed using Maentel-Haenszel formula to obtain odds ratios (ORs) and 95% confidence intervals (CI) with random-effects modeling regardless of heterogeneity. Results: Five studies with a total of 1190 patients and were included in this systematic review and meta-analysis. The use of JAK inhibitors was associated with a reduced risk of mortality (OR 0.51, 95% CI 0.28-0.93, P = 0.02; I 2 : 7.8%, P = 0.354) and clinical improvement (OR 1.76, 95% CI 1.05-2.95, P = 0.032; I 2 : 26.4%, P = 0.253). The use of JAK inhibitors was not associated with a reduced risk of clinical deterioration (OR 0.58, 95% CI 0.28-1.19, P = 0.136; I 2 : 24.1%, P = 0.267). Conclusion: The use of JAK inhibitors was significantly associated with a reduced risk of mortality, and clinical improvement in hospitalized patients with COVID-19.
VOLT : Jurnal Ilmiah Pendidikan Teknik Elektro, 2017
This study aims to create an interactive learning module that qualifies valid, practical and effe... more This study aims to create an interactive learning module that qualifies valid, practical and effective for Computer Assembling subjects in Vocational High School. This research is a Research and Development research conducted in Vocational High School class X West Sumatra. The population of this research is SMK in West Sumatra. Samples are SMKN 6 Padang SMKN 1 Painan, SMKN 2 Pulau Punjung. The results of the assessment of the three validators overall validator test assessment of the Interactive Module of 88.67% so that the level of validity can be interpreted Valid used. Overall assessment of the practicality of the Interactive Module as a learning resource of 86.08%, so the level of practicality can be interpreted Very Practical used. And the effectiveness assessment of Interactive Module as learning resource equal to 85,25%, so the level of effectivity can be interpreted Highly Effective used.
Background: In Indonesia, geriatric population in the year 2005 was 15.8 million (7.2 % populatio... more Background: In Indonesia, geriatric population in the year 2005 was 15.8 million (7.2 % population), and expected to reach 11.34% in the year 2020. There was growing evidence for poor sleep as an independent risk factor for poor physical and mental health. Geriatric population may be particularly vulnerable to effects of sleep disturbance due to significant age-related changes in both sleep and inflammatory regulationObjective: To study the epidemiological (gender, age group) and health status (co-morbidities), sleep quality according to Pittsburgh Sleep Quality Index (PSQI) and its associations in geriatric population hospitalized in General Hospital in Karawaci, Tangerang, Banten Province, Indonesia.Materials and Methods: A hospital based cross sectional study was conducted from January to June 2014. A total of 92 subjects aged 60 years and above were selected consecutively from hospitalized geriatric patients for this study. The data was analyzed by means and proportions.Results:...
The trend of traveling has increased in recent years along with the easy access to information. T... more The trend of traveling has increased in recent years along with the easy access to information. Travelers create the itinerary before they are travelling to an area. However, creating itinerary is not easy, many factors need to be considered before deciding where to go, such as the "must visited" places in that area, distance between tourist attractions to be visited within a day, preferred tourist attractions, and other information about the places. Generating the optimized distance itinerary is similar as a Traveling Salesman Problem (TSP). The purpose of this research is to study the combination of simulated annealing and Greedy algorithms to create an itinerary. The initialization process of the simulated annealing algorithm uses Greedy algorithm searching technique and then proceeded with existing optimization step in simulated annealing method. This paper proposed a method of enhanced simulated annealing algorithm and the experiment results show the enhanced simulated annealing increase the effectiveness of simulated annealing algorithm which produce the shortest distance needed to travel places around an area.
Various Candida species are harmless commensals present in the oral mucous membranes, and Candida... more Various Candida species are harmless commensals present in the oral mucous membranes, and Candida albicans (C. albicans) is the most commonly isolated species. Overgrowth of C. albicans can lead to oral fungal infections, known as oral candidiasis, with multiple local and systemic predisposing factors. Poor oral hygiene (OH) is an important local factor that may increase the risk of oral candidiasis. An immunocompromised patient, such as cancer patient undergoing chemotherapy, has an increased susceptibility to develop oral candidiasis due to an impaired or weakened immune system. The aim of this study was to evaluate C. albicans colony forming units (CFUs) and its relationship with different levels of oral hygiene in cancer patients undergoing chemotherapy. The oral rinse technique was performed to isolate C. albicans from 60 subjects and were cultured on agar plates. Subjects were divided into different groups of OH level according to OHI-S scores. C. albicans were isolated from 44 (73.3%) subjects. There is a strong positive relationship between OH status and CFU ml-1 value (r = 0.708). It showed that oral C. albicans colonization increased significantly in cancer patients undergoing chemotheray with fair and poor OH (p = 0.001). Data from this study revealed a statistically significant relationship between oral hygiene status and C. albicans colonization among cancer patient undergoing chemotherapy. More attention should be paid to oral hygiene as one of the risk factors to be taken into account in the prevention paradigm to reduce the incidence of oral candidiasis among cancer patient undergoing chemotherapy. Further studies with larger sample sizes would be beneficial with the aim of verifying the results obtained in the present study, and consider the interaction effects of other multiple risk factors on the risk of developing oral candidiasis in cancer patients.
Abstrak_Berdasarkan penelitian yang telah dilakukan di Sekolah Menengah Kejuruan Negeri 2 Padang ... more Abstrak_Berdasarkan penelitian yang telah dilakukan di Sekolah Menengah Kejuruan Negeri 2 Padang Jl. DR.Sutomo No. 5, Kel Simpang Haru, Kec. Padang Timur, Kota Padang, Sumatera Barat di kelas X Teknik Komputer dan Jaringan pada semester ganjil, waktu penelitian dilakukan pada tanggal 8 November sampai dengan 14 November 2018 tahun ajaran 2018/2019, diperoleh nilai rata-rata penilaian uji kepraktisan terhadap media mobile learning berbasis web mobile sebesar 87,67%, sehingga tingkat praktikalitasnya dapat di interprestasikan sangat praktis digunakan.. Jadi, dapat disimpulkan bahwa Media Mobile Learning Berbasis Web Mobile mata pelajaran Komputer dan Jaringan Dasar kelas X Teknik Komputer dan Jaringan SMK Negeri 2 Padang layak digunakan untuk proses pembelajaran.
Biosaintifika: Journal of Biology & Biology Education, 2017
Colorectal carcinogenesis induced by cigarette smoke requires at least 30-40 years. This long tim... more Colorectal carcinogenesis induced by cigarette smoke requires at least 30-40 years. This long time duration causes an animal research conducted becomes relevant. This research was carried out to observe colorectal carcinogenesis due to cigarette smoke exposure in Wistar Rat. The observations focused on changes in epithelial morphology and expression of APC, MSH2 and MLH1. Twenty male Wistar rats inbreed strain were randomly allocated into control group and experimental group exposure to cigarettes smoke for 14 weeks and 28 weeks sequentially. Colorectal epithelial morphology was assessed on the histopathology examination, whereas the expression of APC, MSH2 and MLH1 was assessed on aspect of immunohistochemistry. The comparative analysis between the two groups was performed using nonparametric Mann-Whitney U test. Histology of colorectal epithelium showed pattern of colitis associated cancer that was significant both in 14 weeks and 28 weeks of treatment. This research indicated negative expression of APC, MSH2 and MLH1 in the colorectal cancer that were significant at 28 weeks of exposure. This research implies that chronic exposure to cigarette smoke can induce colitis associated colorectal cancer through decreased expression of APC, MSH2 and MLH1.
ABSTRACT Background: Measuring quality of life in breast cancer patients is of importance in asse... more ABSTRACT Background: Measuring quality of life in breast cancer patients is of importance in assessing treatment outcomes. The potential psychological and physical dysfunction caused by both the diagnosis and treatments can have a deleterious impact on the quality of a woman's life. The aim of this study is to evaluate the association of quality
to review the role of ursodeoxycholic acid in acute viral hepatitis. following literature searchi... more to review the role of ursodeoxycholic acid in acute viral hepatitis. following literature searching according to the clinical question on Pubmed and Cochrane Library. After filtered with our inclusion and exclusion criteria, one meta-analysis and two randomized clinical trials are obtained. Through critical appraisal, it was concluded that the articles meet the criteria for validity and relevance. the article found that there is a positive effect of ursodeoxycholic acid on the activity of serum transaminases and cholestasis indexes. However, there is insufficient evidence to support or to refute effects of ursodeoxycholic acid on disease's course as well as the viral load. better method of clinical trials are needed to obtain a valid and applicable result for daily practice.
Penelitian ini akan menjelaskan mengenai proses suksesi pada perusahaan keluarga yang bergerak di... more Penelitian ini akan menjelaskan mengenai proses suksesi pada perusahaan keluarga yang bergerak di bidang konveyor. Tujuan penelitian adalah untuk meneliti suksesi pada perusahaan keluarga yang bergerak di bidang konveyor yang tergolong sukses dam terus bertumbuh setelah proses suksesi tersebut. Metode yang peneliti gunakan yaitu metode kualitatif dengan melakukan wawancara langsung terhadap pemilik perusahaan, observasi dan studi pustaka. Setelah mendapatkan data maka peneliti akan melakukan uji keabsahan data dengan metode triangulasi sumber. Hasil penelitian yaitu pada perencanaan suksesi proses pemilihan calon suksesor sesuai dengan kebutuhan perusahaan namun mentoring harus terus dilangsungkan karena baru berjalan dua tahun. Proses transisi pada perusahaan keluarga yang bergerak di bidang konveyor berjalan mulus karena tidak terjadi hambatan-hambatan pada proses transisi. Evaluasi paska suksesi dinilai menghasilkan performa yang efektif berdasarkan penilaian dari 3 pola yang menyebabkan suksesi menjadi tidak efektif
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