Papers by Gaetano Licitra
Epidemiology, Sep 1, 2012
CRC Press eBooks, Sep 6, 2012
Environments, Apr 4, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Environmental health perspectives, Feb 1, 2018
Rivista Italiana di Acustica, Jun 23, 2015
Il lavoro riporta i risultati di un questionario rivolto a personale tecnico delle Agenzie Ambien... more Il lavoro riporta i risultati di un questionario rivolto a personale tecnico delle Agenzie Ambientali (ARPA-APPA) per rilevarne il grado di consapevolezza e di applicazione dei concetti relativi all'incertezza di misura in acustica ambientale nonché le aspettative e le richieste in materia. I risultati evidenziano che, sebbene la stima dell'incertezza ed il suo impiego nella valutazione di conformità appaiano ad oggi ancora a uno stato embrionale, un'ampia maggioranza di operatori avverte l'importanza di non ignorare l'incertezza nelle proprie valutazioni e sente l'esigenza di disporre di regole decisionali certe e condivise, soprattutto quando il valore misurato è vicino al limite fissato.
Environmental health perspectives, Sep 13, 2011
Background and Aims: Evidence is growing on association between exposure to road traffic noise an... more Background and Aims: Evidence is growing on association between exposure to road traffic noise and health effects, in particular cardiovascular and myocardial infarction (MI). The ongoing study aim...
The purpose of this work was to propose a method for modelling tyre/road noise measured according... more The purpose of this work was to propose a method for modelling tyre/road noise measured according to the CPX protocol on newly laid low-noise road surfaces, using only data available prior to the laying process or through coring tests, such as aggregate grading, fractal dimension, bitumen percentage and air void percentage. CPX levels were modelled using three different frequency ranges (i.e. low, mid and high) and the resulting broadband levels were compared with the experimental ones. The low frequency region includes one-third octave bands from 315 to 800 Hz, the mid-frequency region covers the bands from 1000 to 1600 Hz and the remaining bands from 2000 to 5000 Hz are in the high frequency region. The model developed showed low RMSE, although, due to the limited data available up to date, a tyre different than the Standard Reference Test Tyre (SRTT) was used. The procedure adopted for modelling remains however valid and can be easily followed when data obtained by CPX measurements compliant to the last ISO release will be available.
Journal of Physics: Conference Series, 2022
This paper proposes a system based on Neural Networks (NN), designed for providing an efficient, ... more This paper proposes a system based on Neural Networks (NN), designed for providing an efficient, non-invasive and automated method for monitoring the health status of road pavements by using features derived from Tyre Cavity Noise (TCN) analysis. Indeed, visual inspection remains to date the most common choice for evaluating the condition of road pavements; however, this method is both labor intensive and time consuming. The system presented in this work uses a microphone placed inside the vehicle tyre that measures TCN while travelling normally, and an embedded data acquisition system based on a Raspberry Pi which feeds the NN tools to recognize and classify road deterioration. We also present a preliminary analysis of features based on temporal and spectral characteristics of TCN signals generated by tyre/road interaction and acquired on three different kind of road distresses. The results show good classification capability and, moreover, the sound pressure measured inside the ty...
ISEE Conference Abstracts, 2011
Background and Aims: Evidence is growing on association between exposure to road traffic noise an... more Background and Aims: Evidence is growing on association between exposure to road traffic noise and health effects, in particular cardiovascular and myocardial infarction (MI). The ongoing study aim...
ISEE Conference Abstracts, 2013
Environmental Research, 2021
Introduction: Kidney transplant donors lose 50% of their renal mass after nephrectomy. The remain... more Introduction: Kidney transplant donors lose 50% of their renal mass after nephrectomy. The remaining kidney compensates for this loss and it is estimated that 70% of the baseline renal function prior to donation is recovered. Factors associated with post-donation renal compensation are not well understood. Methods: Retrospective study of 66 consecutive kidney donors (mean age 48.8 years, 74.2% women). We analyzed the potential factors associated with the compensatory mechanisms of the remaining kidney by comparing donors according to their renal compensation rate (RCR) (Group A, infra-compensation [<70%]; Group B, normal compensation [>70%]). Results: We compared Group A (n = 38) and group B (n = 28). Predictors for RCR > 70% were higher baseline creatinine (A vs. B: 0.73 ± 0.14 vs. 0.82 ± 0.11; p = 0.03) and a lower baseline glomerular filtration rate (GFR), estimated both by MDRD-4 (A vs. B: 97.7 ± 18.8 vs. 78.6 ± 9.6 ml/min; p < 0.001) and CKD-EPI (A vs. B: 101.7 ± 15 vs. 88.3 ± 11.7 ml/min; p ≤ 0.001). Age, gender, smoking, hypertension and GFR measured by Tc-DTPA did not show any correlation with the RCR. The multivariate analysis confirmed baseline estimated glomerular filtration rate (eGFR) to be a predictor of compensation: the higher the baseline eGFR, the lower the likelihood of >70% compensation (MDRD-4, OR = 0.94 [95% CI 0.8-0.9], p = 0.01). The compensation rate decreased by 0.4% (p < 0.001) and 0.3% (p = 0.006) for every ml/min increase in baseline eGFR estimated by MDRD-4 and CKD-EPI, respectively. Conclusions: One year after living donor nephrectomy, the remaining kidney partially compensates baseline renal function. In our experience, baseline eGFR is inversely proportional to the one-year renal compensation rate.
Journal of Hypertension, 2017
In hypertensive patients, inappropriately elevated PWV is associated more tightly than observed P... more In hypertensive patients, inappropriately elevated PWV is associated more tightly than observed PWV to younger age and high blood glucose, thus it might help to better depict vascular aging in younger hypertensives and in those with metabolic alterations. A more advanced atherosclerotic process might also contribute to excess aortic stiffness. Whether an inappropriately high PWV translates into an increased cardiovascular risk should be determined in longitudinal studies.
Nutrition, Metabolism and Cardiovascular Diseases, 2017
CD4+CD25hiFoxP3+ cells (2.61 ± 0.25% vs 3.38 ± 0.10%, p<0,01) were significantly decreased in SRE... more CD4+CD25hiFoxP3+ cells (2.61 ± 0.25% vs 3.38 ± 0.10%, p<0,01) were significantly decreased in SREBP1c KO mice. Gene expression and metabolomic analysis of secondary lymphoid organs confirmed that fatty acid synthesis was switched off in SREBP1c KO animals and revealed an impairment in the glycolisis and Kreb cycle which led to a reduced production of ATP. Conclusion: SREBP1c is a key player of intracellular metabolism also in immune cells and its deficiency affected the distribution of T lymphocytes in secondary lymphoid organs, thus suggesting that reprogramming T cell fatty acid syntheisis may represent a therapeutic target for the treatment of diseases characterized by a dysregulated immune activation.
Environment International, 2019
Background: Despite the relevance for occupational safety policies, the health effects of tempera... more Background: Despite the relevance for occupational safety policies, the health effects of temperature on occupational injuries have been scarcely investigated. A nationwide epidemiological study was carried out to estimate the risk of injuries for workers exposed to extreme temperature and identify economic sectors and jobs most at risk. Materials and methods: The daily time series of work-related injuries in the industrial and services sector from the Italian national workers' compensation authority (INAIL) were collected for each of the 8090 Italian municipalities in the period 2006-2010. Daily air temperatures with a 1 × 1 km resolution derived from satellite land surface temperature data using mixed regression models were included. Distributed lag non-linear models (DLNM) were used to estimate the association between daily mean air temperature and injuries at municipal level. A meta-analysis was then carried out to retrieve national estimates. The relative risk (RR) and attributable cases of work-related injuries for an increase in mean temperature above the 75th percentile (heat) and for a decrease below the 25th percentile (cold) were estimated. Effect modification by gender, age, firm size, economic sector and job type were also assessed. Results: The study considered 2,277,432 occupational injuries occurred in Italy in the period 2006-2010. There were significant effects for both heat and cold temperatures. The overall relative risks (RR) of occupational injury for heat and cold were 1.17 (95% CI: 1.14-1.21) and 1.23 (95% CI: 1.17-1.30), respectively. The number of occupational injuries attributable to temperatures above and below the thresholds was estimated to be 5211 per year. A higher risk of injury on hot days was found among males and young (age 15-34) workers occupied in small-medium size firms, while the opposite was observed on cold days. Construction workers showed the highest risk of injuries on hot days while fishing, transport, electricity, gas and water distribution workers did it on cold days. Conclusions: Prevention of the occupational exposure to extreme temperatures is a concern for occupational health and safety policies, and will become a critical issue in future years considering climate change.
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Papers by Gaetano Licitra