Papers by Dr dhiraj nikumbhdhiraj
In 2016, World Health Association (WHO) published the revised classification of urogenital system... more In 2016, World Health Association (WHO) published the revised classification of urogenital system. In this context, multilocular cystic renal cell carcinoma (MCRCC) diagnosis was altered by the terminology as multilocular Cystic Renal Neoplasm of Low Malignant Potential (MCRN-LMP) with ICD code-8316/1. In this mini review we discussed the justification and need of such alteration and the background behind this; in view we published the article on MCRCC in 2011.
IP archives of cytology and histopathology research, Feb 15, 2021
IP archives of cytology and histopathology research, Feb 15, 2021
Epidermoid cyst of the breast is a rare, benign cystic lesion, diagnostically challenging, intere... more Epidermoid cyst of the breast is a rare, benign cystic lesion, diagnostically challenging, interesting entity that may potentially be malignant as well as associated with complications like rupture. We diagnosed an epidermoid cyst of right breast in a 52-year-old female on fine needle aspiration cytology (FNAC). We highlight the role of FNAC in diagnosing such rare but benign entities like epidermoid cyst for effective (simple excision) management of the patients. To the best of our knowledge; only 90 cases of epidermoid cyst of breast were reported in the literature till 2016.
IP archives of cytology and histopathology research, Feb 15, 2021
Journal of Clinical and Diagnostic Research, 2013
IP archives of cytology and histopathology research, Nov 15, 2022
Renal cell carcinoma (RCC) accounts for more than eighty-five percent of primary renal cell carci... more Renal cell carcinoma (RCC) accounts for more than eighty-five percent of primary renal cell carcinomas with male preponderance in 5 t h to 7 t h decades. Collecting duct carcinoma (CDC) constitutes for less than 1% of all renal cell carcinomas. Histopathological examination of all types of RCC is almost importance in view of therapeutic and prognostic implications of its varied subtypes. The purpose of this editorial is to highlight the morphology and rarity of collecting duct carcinoma and differentiation of it from papillary renal cell carcinoma.
IP archives of cytology and histopathology research, Feb 15, 2021
The most common form of scientific misconduct or literary theft in medical science is Plagiarism.... more The most common form of scientific misconduct or literary theft in medical science is Plagiarism. Plagiarism simply means use of writings in any form belonging to others with fabrication and falsification of the data. Research meant creative work on systemic basis to increase our existing knowledge, discover or revise facts and theories. But the boundaries between plagiarism and research are often unclear. Plagiarism may corrupt scientific medical literature and causes harm to patients. It is the most common problem in cytohistopathology also. This article summarizes most common causes and types of plagiarism with ways to avoid any type of plagiarism. Honesty, trust, self satisfaction are the heart of medical scientific articles.The aim of this review is to curtail the plagiarism practice and to create awareness regarding all headings of plagiarism for researchers.
IP archives of cytology and histopathology research, Feb 15, 2021
In 2016, World Health Association (WHO) published the revised classification of urogenital system... more In 2016, World Health Association (WHO) published the revised classification of urogenital system. In this context, multilocular cystic renal cell carcinoma (MCRCC) diagnosis was altered by the terminology as multilocular Cystic Renal Neoplasm of Low Malignant Potential (MCRN-LMP) with ICD code-8316/1. In this mini review we discussed the justification and need of such alteration and the background behind this; in view we published the article on MCRCC in 2011.
Annals of Pathology and Laboratory Medicine, Aug 21, 2016
Background-: Acute appendicitis has remained a clinical entity and an ongoing diagnostic challeng... more Background-: Acute appendicitis has remained a clinical entity and an ongoing diagnostic challenge. Appendicitis is one of the commonest surgical emergencies. However, histopathological studies are the gold standards for diagnosis of acute appendicitis. Though faecoliths are the usual cause of obstruction, other unusual findings can be the cause too, ranging from inflammatory conditions to malignancies. Aims and Objectives: To document and compare unusual histopathological findings in appendectomy specimens in our center. Methods: The clinicopathological records of resected appendices submitted to histopathology department over the period of 4 years from January 2012 to December 2015 were reviewed retrospectively. From accumulated information from 790 appendectomies, 44 appendectomy specimens had unusual histopathological findings were included in the study. Patient who underwent incidental appendectomy during other surgeries were excluded from the study. Results: Out of 790 appendectomy specimens, acute appendicitis accounted for 302(38.2%) with peak occurrence in the age group 11-20 years (38.9%) and 21-30 years (27.7%) with male predominance (2.34:1). Unusual findings were noted in 44 (5.6%) cases by histopathology. Most common findings included obliterative appendicitis (77.3%), followed by eosinophilic appendicitis (6.8%) and granulomatous appendicitis (4.5%).Other unusual findings include diverticulum, mucocele, carcinoid and signet ring adenocarcinoma of the appendix. Conclusion: The gross examination at the time of surgery cannot detect all the abnormalities of the appendix. Although unusual or co-existing pathologies can be rarely seen during appendectomy, all the appendectomy specimens should be sent for routine histopathological examination to avoid missing of any clinically important and treatable condition.
IP archives of cytology and histopathology research, Dec 15, 2020
Carcinoma of unknown primary (CUP) is commonly known as 'occult primary cancer'. It's defined as ... more Carcinoma of unknown primary (CUP) is commonly known as 'occult primary cancer'. It's defined as metastatic malignant cancer confined by pathology in absence of clinically detectable, anatomically defined primary tumor site after an adequate pretreatment diagnostic evaluation. Herein we present a case of 35 year old female of CUP presented with pain in left axillary region that is vague clinical manifestation. Histopathologically it was proved as metastatic adenocarcinoma on axillary mass probably of breast origin. Primary nature is not diagnosed even on IHC. The aim of this case report is to highlight role of ancillary pathology techniques in challenging cases like CUP.
International journal of anatomy and research, Feb 29, 2016
Background: The Supracondylar process is a beak like bony spine/ projection that arises from the ... more Background: The Supracondylar process is a beak like bony spine/ projection that arises from the anteromedial surface of the Humerus. It is also called Supraepitrochlear, epicondylar, epicondylic process or Supracondylar spur. It represents a phylogenetic remnants of complete osseous bride found in climbing animals and many reptiles mostly marsupials, cats, lemurs and American monkeys. Materials and Methods: The two hundred and eighty dried humeri were studied in the Dept of Anatomy, KIMSDU, Karad and ACPM Medical College, Dhule, India. The bones were examined for any osseous projection from distal part under day light. On findings, the dimensions were recorded and photographed. Results: Out of 280 dried humeri examined, we found only 1 humerus of the right side with an osseous spine on the anteromedial surface. The incidence calculated in this study was 0.36%. Conclusion: The Supracondylar process is usually clinically silent but may become symptomatic by presenting as a mass or can be associated with symptoms of median nerve compression and claudication of brachial artery especially when associated with Struthers ligament. Hence the knowledge of the presence of variations in anatomy like Supracondylar process is important for anatomists, radiologists, anesthesiologists, surgeons, and anthropologists.
International journal of anatomy and research, Oct 31, 2015
The variety of multiple morphological variations in the thyroid gland is found as a result of dis... more The variety of multiple morphological variations in the thyroid gland is found as a result of disturbed organogenesis in humans as agenesis, hypoplasia, accessory, ectopy and hemiagenesis. In the routine undergraduate dissection of the thyroid gland, multiple anomalies of the thyroid gland were encountered in 50 and 60 years old female and male cadaver respectively. These were in form of absent isthmus with accessory thyroid lobe in between two lateral lobes, pyramidal lobe arising from left lobe of thyroid with levator glandulae thyroidae in first case. Second case showed narrow isthmus related to first tracheal ring and levator glandulae thyroidae arising from left lobe. In these case studies, we highlight various developmental anomalies of the thyroid gland as absent isthmus, pyramidal lobe and accessory lobe with levator glandulae thyroidae. Hence a thorough knowledge of such morphological variations of thyroid gland helps the surgeons in better planning of safe, effective and uncomplicated operative procedures in resection of thyroid and tracheotomy procedures.
Asian Journal of Medical Sciences, 2023
IP archives of cytology and histopathology research, Jun 15, 2020
Massons's hemangioma is an uncommon, benign and rare vascular tumor. It's often misdiagnosed as s... more Massons's hemangioma is an uncommon, benign and rare vascular tumor. It's often misdiagnosed as soft tissue sarcoma such as angiosarcoma or Kaposi sarcoma. It is also known as intravascular papillary endothelial hyperplasia (IPEH) accounting for 2% of skin and soft tissue vascular tumors. IPEH characterized by exuberant endothelial proliferation within the lumen of medium sized veins. The most common sites affected are head, neck, fingers and trunk. But the occurrence of IPEH in breast is rarely reported in literature. We diagnosed this case in a 2 month old child presented with right breast bud swelling. On histopathology diagnosed as IPEH/ Masson's hemangioma. The aim of this case report to highlight the important role of clinical suspicious of such rare entities and histopathological diagnosis to avoid unnecessary aggressive line of treatment for better management of patient care.
IP archives of cytology and histopathology research, Sep 15, 2021
This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative... more This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
IP archives of cytology and histopathology research, Feb 15, 2021
Cytological interpretation of papillary lesions of the breast remains a challenging task due to i... more Cytological interpretation of papillary lesions of the breast remains a challenging task due to its overlapping features of benign, atypical and malignant subtypes. Papillomas of the breast are relatively rare benign lesions with an incidence of approximately 2-3% in females. This is extremely rare and benign disease in the male breast. We report a case of 50-year-old male patient presented with circumscribed nodular massin his left breast. FNAC was performed and diagnosed as ductal papilloma. In contrast to male breast, benign and malignant lesions are relatively common in females. Such findings are rare in male patients. The goal of the report is to emphasize the role of cytology (fine needle aspiration) in early and accurate diagnosis of papillary lesion of breast in spite of its wide morphological spectrum with overlapping features.
IP archives of cytology and histopathology research, Feb 15, 2021
IP archives of cytology and histopathology research, Jun 15, 2017
Soft tissue nodules around joints can pose a diagnostic challenge to clinicians as well as pathol... more Soft tissue nodules around joints can pose a diagnostic challenge to clinicians as well as pathologist and radiologist. The periarticular nodules have many differentials from inflammatory to neoplastic ones. Gouty tophi is one of differential of these conditions. Fine needle aspiration cytology (FNAC) of these periarticular nodules is important and valuable diagnostic tool for diagnosing gouty tohi in view of its characteristic cytomorphology. We highlight the role of FNAC in diagnosing gouty tophi in 65-year-old female presented with deformed swelling of 2 nd toe of right foot.
International journal of anatomy and research, Mar 31, 2016
Address for Correspondence: Dr. Roopali D. Nikumbh M.D., Assistant Professor, Department Of Anato... more Address for Correspondence: Dr. Roopali D. Nikumbh M.D., Assistant Professor, Department Of Anatomy, JMF’S ACPM Medical College, Dhule, Maharashtra, India. E-Mail: [email protected] Background: Sacrococcygeal teratomas are tumors that arise from sacrococcygeal region containing tissue from all the three germ layers. Sacrococcygeal teratoma (SCT) is a relatively uncommon tumor affecting neonates, infants and children with an incidence of 1 in 40,000 live births with malignant transformation with increasing age. It is four times more common in females than males. Aim and Objectives: To evaluate histological features of congenital sacrococcygeal teratoma and to grade them. Add a note on embryological and clinical aspect of sacrococcygeal teratoma. Material and Methods: The present study was retrospective, descriptive analysis of 10 patients presented with sacrococcygeal mass over the period of 6 years from December 2009 to December 2015 in Department of Anatomy in KIMSU, Karad and Hi-Tech diagnostic center, Dhule. The cases were reviewed histologically and grading of SCT was done and comparisons with other studies were made. Results: We reviewed 10 patients of congenital SCTs. There were 07 girls and 03 boys with the age ranges from 2 months to 18 months. Majority of the cases were less than 3 months. There were 08 cases of mature and 02 cases of immature teratoma noted. The most common presentation was sacrococcygeal mass in both teratomas. Conclusion: Majority of the SCTs are benign on histology, when diagnosed at birth with fully differentiated tissues. Histologically meticulous and careful search for immature or malignant components should be instituted as it will helps in therapeutic decisions. Additionally embryological studies and chromosomal analysis of SCTs in large series may be warranted to predict the further prognosis.
Background: Aspergillosis of head and neck region primarily affect nose and paranasal sinuses. My... more Background: Aspergillosis of head and neck region primarily affect nose and paranasal sinuses. Mycotic infections are raising globally both in immunocompetent and immunocompromised individuals. These infections mimic malignancy clinically and radiologically. They pose a diagnostic and therapeutic challenge to the physician. In such cases, aspiration cytology plays a crucial role in early and definitive diagnosis of mycotic infections. Case Presentation: We herein present a case of 75-year-old male presented to the surgical department of our hospital with right maxillary region swelling with a discharging sinus since 2months. Clinically suspected as sebaceous cyst/malignancy. Fine needle aspiration cytology (FNAC) was advised and showed giant cell lesion with fungal hyphae, morphologically suggestive of Aspergillosis. Conclusions: Early diagnosis with aspiration cytology will help the clinician for prompt and appropriate management and follow up in order to reduce the morbidity and mortality associated with its destructive nature. The goal of this case report was to highlight the importance of FNAC in diagnosing subcutaneous mycotic infections promptly and to avoid further complications of the disease.
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Papers by Dr dhiraj nikumbhdhiraj