Background: Spinal anesthesia (SA) is a good alternative to general anesthesia (GA) for spine sur... more Background: Spinal anesthesia (SA) is a good alternative to general anesthesia (GA) for spine surgery. Despite that, a few case series concern the use of thoracic spinal anesthesia for short-duration surgical interventions. In search of an alternative approach to GA and a better opioid-free modality, we aimed to investigate the safety, feasibility, and patient satisfaction of thoracic SA for spine surgery. Materials and methods: We analyzed retrospectively a cohort of 24 patients operated on for a degenerative and osteoporotic pathology of the lower thoracic and lumbar spine. Data was collected from medical records, including clinical notes, operative and anesthesia records, and patient questionnaires. Results: Twenty-one surgeries for herniated discs, two for degenerative spinal stenosis, and one for multi-level osteoporotic vertebral body fractures were performed under spinal anesthesia with intrathecal sedation. In all cases, we applied 0.5% isobaric bupivacaine and the following adjuvants: midazolam, clonidine or dexmedetomidine, and dexamethasone. We boosted the anesthesia with local ropivacaine due to inefficient sensory block in two patients. Nobody in the cohort received intravenous opioids, non-steroidal anti-inflammatory drugs, or additional sedation intraoperatively. Postoperative painkillers were upon the patient's request. No significant complications were detected. Conclusion: Thoracic spinal anesthesia incorporating adjuvants such as midazolam, clonidine or dexmedetomidine, and dexamethasone demonstrates not only efficient conditions for spine surgery, a favorable safety profile, high patient satisfaction, and intrathecal sedation but also effective opioid-free pain management.
With a wide range of etiologies, low back pain (LBP) presents a true clinical challenge, finding ... more With a wide range of etiologies, low back pain (LBP) presents a true clinical challenge, finding its origins both in intrinsic spinal and systemic conditions, as well as referred ones. This review categorizes the LBP into these three groups and aims to offer a comprehensive look at the tools required to diagnose and differentiate them. The intrinsic etiologies are based on conditions that affect the musculoskeletal components of the lumbar spine, such as intervertebral disc disease, stenosis, muscular imbalance, and facet joint degeneration. The systemic causes usually extend beyond local structures. Such are the cases of neoplasia, infections, and chronic inflammation. The diagnosis is rendered even more complex by adding the referred pain, which only manifests in the lower back yet arises in more distant locations. By synthesizing the literature that encompasses the problem, this review aims to augment the understanding of the differential diagnoses of LBP by showcasing the subject's nuances. This categorization provides a structured approach to a patient-centered diagnosis, which could facilitate the medical practitioners' efforts to navigate this pathology more effectively.
Introduction: More than 30 years after the initial experience of Galibert and Deramond with percu... more Introduction: More than 30 years after the initial experience of Galibert and Deramond with percutaneous vertebroplasty, the procedure has gone through countless refinements and clinical evaluations. Predictors for the success and failure of the procedure in the literature vary and are focused on the duration of complaints, type of fracture, presence of edema on MRI scans, etc. We propose using a quantitative method based on a standard CT examination of the thoracic or lumbar spine to assess the risks and potential success of performing vertebroplasty. Materials and methods: This is a single-center prospective observational study on 139 patients treated with percutaneous vertebroplasty (pVPL) for a single symptomatic osteoporotic vertebral compression fracture (OVCF). We measured the levels of disability and pain preoperatively and again at the 3-, 6-and 12-month marks using the standardized VAS and ODI questionnaires. Every patient in the study was evaluated with postoperative multidetector CT (MDCT) to determine the presence, extent, and localization of vertebral cement leakage and to measure the adjacent vertebrae's minimal and mean density in Hounsfield units (HU min and HU mean , respectively). Results: We determined that a slight (r = −0.201) but statistically significant (p = 0.018) correlation existed between HU measurements taken from radiologically intact adjacent vertebrae and the procedure's effect concerning the pain levels at the 3-month follow-up. This correlation failed to reach statistical significance at 12 months (p = 0.072). We found no statistically significant relationship between low vertebral cancellous bone density and cement leakage on postoperative scans (p = 0.6 for HU min and p = 0.74 for HU mean). Conclusion: We have moderately strong data that show a negative correlation between the mean values of vertebral cancellous bone density in patients with OVCF and the effect of pVPL in reducing pain. Lower bone densities, measured this way, showed no increased risk of cement leakage.
Background: The non traumatic, post inflammatory atlantoaxial rotatory instability, also known as... more Background: The non traumatic, post inflammatory atlantoaxial rotatory instability, also known as Grisel’s syndrome is a relatively rare condition usually affecting children. Adult cases are rare and even less frequently reported with separate case reports describing a single patient. Although antibiotic treatment and close neurological monitoring seem to be the gold standard of care, there is no general consensus on the optimal timing and extent of the surgical treatment. Case Description: We present a case of C1-C2 spondylitis, secondary to retropharyngeal abscess, without atlantoaxial instability on initial evaluation that progressed to C1-C2 subluxation with rapidly developing myelopathy 3 months after optimal antibiotic therapy and complete clinical and biochemical remission. Conclusion: Grisel’s syndrome is a rare condition in adults with secondary instability in spite of successful antibacterial treatment, which requires decompression and delayed surgical fixation in our case.
The aim of the current study is to present the possibilities for minimally invasive percutaneous ... more The aim of the current study is to present the possibilities for minimally invasive percutaneous procedures for surgical treatment of osteoporotic compression fractures of the vertebrae (OVCF), expressed in vertebroplasty and balloon kyphoplasty. We compare their therapeutic effect with that of conservative treatment and present conclusions from the world literature regarding the safety of these procedures. Material and methods: We used data from our surgical experience for the last 10 years. We took into account the relevant literature from the global PubMed database and Google Scholar to present randomized clinical trials and meta-analyzes comparing OVCF treatment methods. We analyzed those who assessed the quality of life, pain, and complications of treatment. Results: The world experience shows an excellent result in the short term from the minimally invasive percutaneous procedures. In the long term some authors note a significant overlap of the results with the conservative me...
The facet syndrome is a unilateral or bilateral pain originating from the intervertebral joint. I... more The facet syndrome is a unilateral or bilateral pain originating from the intervertebral joint. Its frequency reaches 30% of the population of patients with low back pain. Inflammation plays a significant role in cartilage degeneration and the development of osteoarthritis, and also significantly contributes to swelling with overstretching of the joint capsule and irritation of nociceptive receptors. Minimally invasive interventional approaches play a significant role in the treatment of facet syndrome. This review systemize the ways to treat the pain through corticosteroid infiltrations and interventional denervations of the intervertebral joint, which may be complementary techniques. The literature is analyzed and our experience is presented.
Background: Spinal anesthesia (SA) is a good alternative to general anesthesia (GA) for spine sur... more Background: Spinal anesthesia (SA) is a good alternative to general anesthesia (GA) for spine surgery. Despite that, a few case series concern the use of thoracic spinal anesthesia for short-duration surgical interventions. In search of an alternative approach to GA and a better opioid-free modality, we aimed to investigate the safety, feasibility, and patient satisfaction of thoracic SA for spine surgery. Materials and methods: We analyzed retrospectively a cohort of 24 patients operated on for a degenerative and osteoporotic pathology of the lower thoracic and lumbar spine. Data was collected from medical records, including clinical notes, operative and anesthesia records, and patient questionnaires. Results: Twenty-one surgeries for herniated discs, two for degenerative spinal stenosis, and one for multi-level osteoporotic vertebral body fractures were performed under spinal anesthesia with intrathecal sedation. In all cases, we applied 0.5% isobaric bupivacaine and the following adjuvants: midazolam, clonidine or dexmedetomidine, and dexamethasone. We boosted the anesthesia with local ropivacaine due to inefficient sensory block in two patients. Nobody in the cohort received intravenous opioids, non-steroidal anti-inflammatory drugs, or additional sedation intraoperatively. Postoperative painkillers were upon the patient's request. No significant complications were detected. Conclusion: Thoracic spinal anesthesia incorporating adjuvants such as midazolam, clonidine or dexmedetomidine, and dexamethasone demonstrates not only efficient conditions for spine surgery, a favorable safety profile, high patient satisfaction, and intrathecal sedation but also effective opioid-free pain management.
With a wide range of etiologies, low back pain (LBP) presents a true clinical challenge, finding ... more With a wide range of etiologies, low back pain (LBP) presents a true clinical challenge, finding its origins both in intrinsic spinal and systemic conditions, as well as referred ones. This review categorizes the LBP into these three groups and aims to offer a comprehensive look at the tools required to diagnose and differentiate them. The intrinsic etiologies are based on conditions that affect the musculoskeletal components of the lumbar spine, such as intervertebral disc disease, stenosis, muscular imbalance, and facet joint degeneration. The systemic causes usually extend beyond local structures. Such are the cases of neoplasia, infections, and chronic inflammation. The diagnosis is rendered even more complex by adding the referred pain, which only manifests in the lower back yet arises in more distant locations. By synthesizing the literature that encompasses the problem, this review aims to augment the understanding of the differential diagnoses of LBP by showcasing the subject's nuances. This categorization provides a structured approach to a patient-centered diagnosis, which could facilitate the medical practitioners' efforts to navigate this pathology more effectively.
Introduction: More than 30 years after the initial experience of Galibert and Deramond with percu... more Introduction: More than 30 years after the initial experience of Galibert and Deramond with percutaneous vertebroplasty, the procedure has gone through countless refinements and clinical evaluations. Predictors for the success and failure of the procedure in the literature vary and are focused on the duration of complaints, type of fracture, presence of edema on MRI scans, etc. We propose using a quantitative method based on a standard CT examination of the thoracic or lumbar spine to assess the risks and potential success of performing vertebroplasty. Materials and methods: This is a single-center prospective observational study on 139 patients treated with percutaneous vertebroplasty (pVPL) for a single symptomatic osteoporotic vertebral compression fracture (OVCF). We measured the levels of disability and pain preoperatively and again at the 3-, 6-and 12-month marks using the standardized VAS and ODI questionnaires. Every patient in the study was evaluated with postoperative multidetector CT (MDCT) to determine the presence, extent, and localization of vertebral cement leakage and to measure the adjacent vertebrae's minimal and mean density in Hounsfield units (HU min and HU mean , respectively). Results: We determined that a slight (r = −0.201) but statistically significant (p = 0.018) correlation existed between HU measurements taken from radiologically intact adjacent vertebrae and the procedure's effect concerning the pain levels at the 3-month follow-up. This correlation failed to reach statistical significance at 12 months (p = 0.072). We found no statistically significant relationship between low vertebral cancellous bone density and cement leakage on postoperative scans (p = 0.6 for HU min and p = 0.74 for HU mean). Conclusion: We have moderately strong data that show a negative correlation between the mean values of vertebral cancellous bone density in patients with OVCF and the effect of pVPL in reducing pain. Lower bone densities, measured this way, showed no increased risk of cement leakage.
Background: The non traumatic, post inflammatory atlantoaxial rotatory instability, also known as... more Background: The non traumatic, post inflammatory atlantoaxial rotatory instability, also known as Grisel’s syndrome is a relatively rare condition usually affecting children. Adult cases are rare and even less frequently reported with separate case reports describing a single patient. Although antibiotic treatment and close neurological monitoring seem to be the gold standard of care, there is no general consensus on the optimal timing and extent of the surgical treatment. Case Description: We present a case of C1-C2 spondylitis, secondary to retropharyngeal abscess, without atlantoaxial instability on initial evaluation that progressed to C1-C2 subluxation with rapidly developing myelopathy 3 months after optimal antibiotic therapy and complete clinical and biochemical remission. Conclusion: Grisel’s syndrome is a rare condition in adults with secondary instability in spite of successful antibacterial treatment, which requires decompression and delayed surgical fixation in our case.
The aim of the current study is to present the possibilities for minimally invasive percutaneous ... more The aim of the current study is to present the possibilities for minimally invasive percutaneous procedures for surgical treatment of osteoporotic compression fractures of the vertebrae (OVCF), expressed in vertebroplasty and balloon kyphoplasty. We compare their therapeutic effect with that of conservative treatment and present conclusions from the world literature regarding the safety of these procedures. Material and methods: We used data from our surgical experience for the last 10 years. We took into account the relevant literature from the global PubMed database and Google Scholar to present randomized clinical trials and meta-analyzes comparing OVCF treatment methods. We analyzed those who assessed the quality of life, pain, and complications of treatment. Results: The world experience shows an excellent result in the short term from the minimally invasive percutaneous procedures. In the long term some authors note a significant overlap of the results with the conservative me...
The facet syndrome is a unilateral or bilateral pain originating from the intervertebral joint. I... more The facet syndrome is a unilateral or bilateral pain originating from the intervertebral joint. Its frequency reaches 30% of the population of patients with low back pain. Inflammation plays a significant role in cartilage degeneration and the development of osteoarthritis, and also significantly contributes to swelling with overstretching of the joint capsule and irritation of nociceptive receptors. Minimally invasive interventional approaches play a significant role in the treatment of facet syndrome. This review systemize the ways to treat the pain through corticosteroid infiltrations and interventional denervations of the intervertebral joint, which may be complementary techniques. The literature is analyzed and our experience is presented.
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