Papers by Carlos Mercapide
Rev Argent Cir, Dec 1, 1992
Acta gastroenterologica Latinoamericana, 2015
Hydatidosis (cystic echinococcosis) is endemic in Rio Negro Province, Argentina. In 1980 started ... more Hydatidosis (cystic echinococcosis) is endemic in Rio Negro Province, Argentina. In 1980 started a control program against the disease. In 1984 Frider et al performed the first ultrasound screening in the world at Pilcaniyeu city, later extended to other localities of Rio Negro province. The initial prevalence in asymptomatic people was 7.1% in Pilcaniyeu and 10.1% in Comallo, being all new cases and with surgical indication. The aim of this investigation was to determine the current prevalence and analyze the evolution of the disease across 25 years of the control program. In 2009 and 2010 ultrasound screening studies were conducted in both locations in all age groups. In 512 ultrasound studies at Pilcaniyeu, the prevalence was 1.5% in children (6 to 14years old) and 4.2% in adults (total 2.5%). In 770 ultrasound studies at Comallo, the prevalence was 1.1 %in children and 6.6% in adults (total 3.0%). The overall reduction in the prevalence reached 67.2%. Regarding the age distribut...
Boletín chileno de parasitología, 2000
Así, el objetivo del presente trabajo es analizar los costos para los servicios de salud de la Pr... more Así, el objetivo del presente trabajo es analizar los costos para los servicios de salud de la Provincia de Río Negro, Argentina, la atención médica de los casos económicamente alternativas futuras en las estrategias de control. Para ello se obtuvo información de casos humanos ...
Epidemiological surveillance of cystic echinococcosis in dogs, sheep farms and humans in the Rio ... more Epidemiological surveillance of cystic echinococcosis in dogs, sheep farms and humans in the Rio Negro Province. The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 1980-2002 included serological and ultrasonographic screening in humans and arecoline test in dogs. In lieu of the limitations of the arecoline test the proposal was to supplant that test for
Medicina, 2006
The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 198... more The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 1980-2002 included serological and ultrasonographic screening in humans and arecoline test in dogs. In lieu of the limitations of the arecoline test the proposal was to supplant that test for the copro ELISA-copro/Western Blot complex applied to feces collected from the environment. The objective was to compare the pros and cons of the two tests and to evaluate the human and the canine infection prevalence. The working area encompassed 7 Departments with systematic canine parasiticide activities (Program Area) and 4 Departments, not endemic, as Control Area. The arecoline test was applied to the dogs in assembled groups with the voluntary participation of their owners (not randomized sampling). Samples for the detection of coproantigens were obtained from sheep farms selected at random and analyzed by the complex copro-ELISA /Western Blot. Prevalence in man was determined by screening the s...
Revista Panamericana de Salud Pública, 2000
debe dirigirse a Edmundo Larrieu, a la siguiente dirección postal: Laprida 240 (8599) Viedma, Arg... more debe dirigirse a Edmundo Larrieu, a la siguiente dirección postal: Laprida 240 (8599) Viedma, Argentina. Correo electrónico: msrione@anmat. gov.ar ABSTRACT Asymptomatic carriers of hydatidosis: epidemiology, diagnosis, and treatment
Liver International, 2010
The management of hydatid liver disease (HLD) includes various nonsurgical and surgical treatment... more The management of hydatid liver disease (HLD) includes various nonsurgical and surgical treatment options. The purpose of the present longitudinal study was to report the changes in surgical management and the consequent outcome of HLD patients in 10 referral surgical centres in Argentina from 1975 to 2007. The study result analysis was divided into two study periods (1975-1990 and 1991-2007). A total of 1412 patients underwent radical (Group 1: 396 patients), conservative (Group 2: 748 patients) or combined (Group 3: 536 interventions in 268 patients) surgical procedures. The overall mortality and complication rate (Clavien I-IV) was 1.8 and 39% respectively. The complication rate was significantly lower in Group 1 (26%) compared with Group 2 (45%) and Group 3 (42%) There was a significant decrease in mortality (2.3 vs. 1%), complication (42 vs. 34%) and early reoperation (12 vs. 6%) rates between the first study part (918 patients) and the second study part (494 patients). During a median follow-up of 7 years, there was a significant decrease in the first part of this study in the late reoperation rate (8.4-3%) and in disease recurrence (9-1.6%). This large national observational multicentre series shows a significant improvement in surgical management of HLD in Argentina, with a decrease in mortality, morbidity, early and late reoperation and recurrence rates. A recent trend was observed in favour of an earlier diagnosis, less complicated clinical presentation and recent use of minimally invasive approaches.
Arch. argent. …, 2002
Resumen Introducción . La hidatidosis o equinococosis quís-tica producida por el Echinococcus gra... more Resumen Introducción . La hidatidosis o equinococosis quís-tica producida por el Echinococcus granulosus es una enfermedad endémica en la provincia de Río Ne-gro, Argentina. Catastros ecográficos efectuados en la provincia de Río Negro en el año 1984 en tres ...
Acta Tropica, 2004
Hydatidosis or cystic echinococcosis (CE) caused by Echinococcus granulosus is endemic in the Pro... more Hydatidosis or cystic echinococcosis (CE) caused by Echinococcus granulosus is endemic in the Province of Río Negro, Argentina. The objective of this investigation was to evaluate the results of a program carried out in endemic areas of the Province of Río Negro, Argentina, in the years 1997-2002. Abdominal ultrasonography was used, classifying the cases detected according to WHO guidelines. A treatment algorithm was defined which included observation, albendazol therapy, PAIR or surgery, according to cyst type and size.
Acta Tropica, 2011
Cystic echinococcosis is an endemic disease in the Province of Rio Negro, Argentina. Ultrasound s... more Cystic echinococcosis is an endemic disease in the Province of Rio Negro, Argentina. Ultrasound surveys carried out in 1984 found prevalence rates of 5.6% in children between 6 and 14 years of age. Objective: To describe and to evaluate the results of the strategy applied in school children by hospital services of the Province of Rio Negro with regard to diagnosis, treatment and monitoring of cystic echinococcosis and to evaluate simultaneously the results of the control program against cystic echinococcosis. Materials and methods: In 1997 ultrasound was chosen to carry out population surveys and the medical treatment criteria for the detected cases were standardized. The population under study involved 5745 students in the first survey and 22,793 in subsequent studies. The detected cases were classified according to Gharbi's scheme. A treatment algorithm was defined based only on monitoring ("watch and wait"), albendazole, surgery (open or laparoscopic) or mini-invasive procedures, according to type, location and size of the cyst. Information was also obtained on cases notified to the Health System between 1980 and 2008. Results: In the first survey, 70 carriers (1.2%) were detected; of these, 25 started albendazole treatment (35.7%) and only 3 (4.3%) underwent surgery. Ten years after treatment, 60.1% of 42 cases, presented Types IV and V cysts and 14.5% presented total involution of their cysts. In subsequent studies, 87 (0.4%) cases were detected, 49 of which started albendazole treatment (56.3%) and 9 underwent surgery (10.3%). The incidence rate of cystic echinococcosis cases decreased from 38 × 100,000 in 1980 to 3.7 × 100,000 in 2008. Discussion: A strong decrease in cystic echinococcosis was obtained although persistent levels of transmission were maintained. The cases produced under these conditions are diagnosed by means of ultrasound surveys and are treated using a plan based on albendazole and monitoring by the Health System during a period of 10 years.
PLoS neglected tropical diseases, 2012
Cystic echinococcosis (CE) is a chronic, complex and neglected disease caused by the larval stage... more Cystic echinococcosis (CE) is a chronic, complex and neglected disease caused by the larval stage of Echinococcus granulosus. The effects of this neglect have a stronger impact in remote rural areas whose inhabitants have no chances of being diagnosed and treated properly without leaving their jobs and travelling long distances, sometimes taking days to reach the closest referral center. In 1980 our group set up a control program in endemic regions with CE in rural sections of Rio Negro, Argentina. Since 1997, we have used abdominopelvic ultrasound (US) as a screening method of CE in school children and determined an algorithm of treatment. To describe the training system of general practitioners in early diagnosis and treatment of CE and to evaluate the impact of the implementation of the field program. In 2000, to overcome the shortage of radiologists in the area, we set up a short training course on Focused Assessment with Sonography for Echinococcosis (FASE) for general practiti...
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Papers by Carlos Mercapide