Papers by Batkhuyag Purevjav
Proceedings for Annual Meeting of The Japanese Pharmacological Society
Central Asian Journal of Medical Sciences
Objective: To study the effect of traditional medicine Anar-5 on the development of chronic gastr... more Objective: To study the effect of traditional medicine Anar-5 on the development of chronic gastritis in rat gastric mucosa. Methods: Rats were orally administered deoxycholate sodium 1ml/100 gm or a combination of deoxycholate 1 ml/100 gm and Anar-5 at Anar-5 100 mg/kg or 200 mg/kg for 4, 8, and 12 weeks to determine the protective effect of Anar-5. Serum gastrin levels were measured to determine the impact of Anar-5. Gastric specimens were prepared for light microscopy with hematoxylin and eosin and PAS stains. The damage of barrier in mucosa with erosion or ulceration, and the thickness of mucin were examined using light microscopy. The serum levels of gastrin were measured with ELISA method. Results: Under light microscopy, the gastric mucosa was diffusely eroded or ulcerated and the thickness of mucin was decreased in rats not treated with Anar-5. The levels of gastrin in serum were significantly lower in chronic atrophic gastritis rats than that in normal rats (p<0.05). Dou...
Journal of the Neurological Sciences, Oct 1, 2019
Poster Session 1 The results of the study on brain stroke during pregnancy and postpartum period
Gendering the Field. Towards Sustainable Livelihoods for Mining Communities, 2011
Diagnostic Pathology, 2018
Background: Chronic gastritis is a slowly progressive disease. It includes atrophy of gastric muc... more Background: Chronic gastritis is a slowly progressive disease. It includes atrophy of gastric mucosa, impairment of epithelial regeneration, formation of lymphoid tissue/germinal center, loss of gastric secretion and movement. The Mongolian traditional medicine used Anar-5 recipes for the treatment of stomachache, emesis, and improvement of gastricdigestion. Based on these observations, we implemented a rat model of Anar-5 treatment in artificial chronic gastritis in order to elucidate its potential protective mechanisms scientifically.Methods and material: We established an experimental rat model of chronic gastritis by use of ammonia water. We divided the rat cohorts in an Anar-5–treated test group, an untreated cohort, and a control group. The untreated group was fed with 0.1% ammonia water and the treated group with both 0.1% ammonia water and administered Anar-5 100 mg/kg/day for 6 weeks. Gastric lesions were evaluated microscopically. The Prostaglandin E2 levels, cyclooxygenas...
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Papers by Batkhuyag Purevjav