Vol. 3, No. 4, 2018 by Asma Mustafa
Research Article, Dec 2018
Thalassemia is a common inherited disorder in Pakistan with around 5000 new cases diagnosed every... more Thalassemia is a common inherited disorder in Pakistan with around 5000 new cases diagnosed every year. Despite various preventive measures taken at the national level, the disease burden is still not declining. In this study the incidence of ß Thalassemia trait among pregnant females presenting to a tertiary care hospital is measured.
Methods: This study was conducted at Pakistan Institute of Medical sciences. 102 Pregnant females who were referred to us for hemoglobin
electrophoresis from July 2017-June 2018 were included. Complete blood count, peripheral film, reticulocyte count and hemoglobin
electrophoresis was performed for each patient.
Results: The mean age was 25 years and the mean period of gestation was 30.30 weeks. Out of 102 patients, 5 (4.9%) were diagnosed as ß
Thalassemia trait. Of these, 2 (40%) did not have a positive family history of Thalassemia. We compared the results of our study with those
done at different regions of Pakistan and found variable incidence of carrier state in different regions of the country.
Conclusion: Antenatal screening is a forward step towards minimizing incidence of Thalassemia in Pakistan however clinicians should be
directed to refer these patients in early pregnancy
Papers by Asma Mustafa
National journal of health sciences, Feb 21, 2019
Hematology & Transfusion International Journal, 2018
Background: Bone Marrow Biopsy is used as an intervention to diagnose certain hematological and s... more Background: Bone Marrow Biopsy is used as an intervention to diagnose certain hematological and systemic diseases as an adjunct to routine laboratory investigations. The procedure includes getting an aspirate and a trephine biopsy. Slides/Smears are prepared from the aspirate and touch imprints along with Hematoxylin and Eosin (H and E) stained sections are prepared from the trephine. Traditionally the slides from the aspirate have been prepared directly (without anticoagulants) and examined along with the trephine biopsy sections to reach a diagnosis. EDTA (Ethylene Diammine Tetra Acetate) preserved specimen can also be used to make slides of the aspirate. Objective: To compare two methods of bone marrow aspirate preparation. Design of study: Randomized controlled trial. Place of study: Department of Pathology, Pakistan Institute of Medical Sciences, Islamabad Materials and methods: Patients coming to the Department of Pathology for bone marrow biopsy had their samples taken. Half ...
National Journal of Health Sciences, 2018
Introduction: Thalassemia is a common inherited disorder in Pakistan with around 5000 new cases d... more Introduction: Thalassemia is a common inherited disorder in Pakistan with around 5000 new cases diagnosed every year. Despite various preventive measures taken at the national level, the disease burden is still not declining. In this study the incidence of ß Thalassemia trait among pregnant females presenting to a tertiary care hospital is measured. Methods: This study was conducted at Pakistan Institute of Medical sciences. 102 Pregnant females who were referred to us for hemoglobin electrophoresis from July 2017-June 2018 were included. Complete blood count, peripheral film, reticulocyte count and hemoglobin electrophoresis was performed for each patient. Results: The mean age was 25 years and the mean period of gestation was 30.30 weeks. Out of 102 patients, 5 (4.9%) were diagnosed as ß Thalassemia trait. Of these, 2 (40%) did not have a positive family history of Thalassemia. We compared the results of our study with those done at different regions of Pakistan and found variable incidence of carrier state in different regions of the country. Conclusion: Antenatal screening is a forward step towards minimizing incidence of Thalassemia in Pakistan however clinicians should be directed to refer these patients in early pregnancy.
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Vol. 3, No. 4, 2018 by Asma Mustafa
Methods: This study was conducted at Pakistan Institute of Medical sciences. 102 Pregnant females who were referred to us for hemoglobin
electrophoresis from July 2017-June 2018 were included. Complete blood count, peripheral film, reticulocyte count and hemoglobin
electrophoresis was performed for each patient.
Results: The mean age was 25 years and the mean period of gestation was 30.30 weeks. Out of 102 patients, 5 (4.9%) were diagnosed as ß
Thalassemia trait. Of these, 2 (40%) did not have a positive family history of Thalassemia. We compared the results of our study with those
done at different regions of Pakistan and found variable incidence of carrier state in different regions of the country.
Conclusion: Antenatal screening is a forward step towards minimizing incidence of Thalassemia in Pakistan however clinicians should be
directed to refer these patients in early pregnancy
Papers by Asma Mustafa
Methods: This study was conducted at Pakistan Institute of Medical sciences. 102 Pregnant females who were referred to us for hemoglobin
electrophoresis from July 2017-June 2018 were included. Complete blood count, peripheral film, reticulocyte count and hemoglobin
electrophoresis was performed for each patient.
Results: The mean age was 25 years and the mean period of gestation was 30.30 weeks. Out of 102 patients, 5 (4.9%) were diagnosed as ß
Thalassemia trait. Of these, 2 (40%) did not have a positive family history of Thalassemia. We compared the results of our study with those
done at different regions of Pakistan and found variable incidence of carrier state in different regions of the country.
Conclusion: Antenatal screening is a forward step towards minimizing incidence of Thalassemia in Pakistan however clinicians should be
directed to refer these patients in early pregnancy