objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective int... more It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective intrauterine growth restriction diagnosed at 18 weeks in the second twin and significant weight discordance, with intermittently absent end-diastolic umbilical artery flow. Possible etiology, diagnosis, classification, clinical outcome and prognosis are discussed. This is not a situation of wide acceptance yet, but in recent studies it seems to identify a subgroup with a high risk of death in the smaller twin and neurological damage in the other one.
objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective int... more It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective intrauterine growth restriction diagnosed at 18 weeks in the second twin and significant weight discordance, with intermittently absent end-diastolic umbilical artery flow. Possible etiology, diagnosis, classification, clinical outcome and prognosis are discussed. This is not a situation of wide acceptance yet, but in recent studies it seems to identify a subgroup with a high risk of death in the smaller twin and neurological damage in the other one.
Objective: To evaluate and compare the management and associated morbidity in inborn and outborn ... more Objective: To evaluate and compare the management and associated morbidity in inborn and outborn babies with meconium aspiration syndrome admitted to the Neonatal Intensive Care Unit and ventilated with high frequency oscillatory ventilation. Methods: A retrospective cohort study with a review of clinical data from newborns, admitted to the Neonatal Intensive Care Unit during a six-year period (from 1999 to 2004) and ventilated with early high frequency oscillatory ventilation, first intention in inborns and immediately after Neonatal Intensive Care Unit arrival in outborns. results: In the present study, 27 newborns were included: 12 inborn and 15 outborn infants. Severity criteria were similar in both groups. The pulmonary morbidity associated was severe persistent pulmonary hypertension -12 (seven outborns), pneumothorax -five (three outborns), interstitial emphysema -two (one outborn) and pulmonary hemorrhageone outborn. Hypoxic-ischemic encephalopathy II-III occurred in six newborns (four outborns). The therapeutic procedures were surfactant administration in 22 newborns (13 outborns), nitric oxide in 12 newborns (7 outborns) and magnesium sulphate in four newborns (three outborns). The median length of ventilation was six days (inborn infants: four and half days; outborn infants: ten days) and the median length of oxygenation supply was ten days (inborn infants: four and half days; outborn infants: 15 days). The median length of stay was 13 days (inborn infants: 11 days; outborn infants: 16 days). One outborn infant died. conclusions: With this ventilation strategy, we have found no significant statistical differences between the two newborn groups, except for the length of oxygenation supply that was longer in the Outborn Group.
objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective int... more It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective intrauterine growth restriction diagnosed at 18 weeks in the second twin and significant weight discordance, with intermittently absent end-diastolic umbilical artery flow. Possible etiology, diagnosis, classification, clinical outcome and prognosis are discussed. This is not a situation of wide acceptance yet, but in recent studies it seems to identify a subgroup with a high risk of death in the smaller twin and neurological damage in the other one.
objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high ... more Objective: To evaluate the clinical outcome of very low birth weight newborns, submitted to high frequency oscillatory ventilation with a strategy of early lung volume optimization. Methods: Descriptive prospective study in a nine-year period, between 1999 January 1st to 2008 January 1st. All the very low birth weight newborns were born in Dr. Alfredo da Costa Maternity, Lisbon, Portugal, were
It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective int... more It is reported the clinical case of a biamnionic monochorionic twin gestation, with selective intrauterine growth restriction diagnosed at 18 weeks in the second twin and significant weight discordance, with intermittently absent end-diastolic umbilical artery flow. Possible etiology, diagnosis, classification, clinical outcome and prognosis are discussed. This is not a situation of wide acceptance yet, but in recent studies it seems to identify a subgroup with a high risk of death in the smaller twin and neurological damage in the other one.
Objective: To evaluate and compare the management and associated morbidity in inborn and outborn ... more Objective: To evaluate and compare the management and associated morbidity in inborn and outborn babies with meconium aspiration syndrome admitted to the Neonatal Intensive Care Unit and ventilated with high frequency oscillatory ventilation. Methods: A retrospective cohort study with a review of clinical data from newborns, admitted to the Neonatal Intensive Care Unit during a six-year period (from 1999 to 2004) and ventilated with early high frequency oscillatory ventilation, first intention in inborns and immediately after Neonatal Intensive Care Unit arrival in outborns. results: In the present study, 27 newborns were included: 12 inborn and 15 outborn infants. Severity criteria were similar in both groups. The pulmonary morbidity associated was severe persistent pulmonary hypertension -12 (seven outborns), pneumothorax -five (three outborns), interstitial emphysema -two (one outborn) and pulmonary hemorrhageone outborn. Hypoxic-ischemic encephalopathy II-III occurred in six newborns (four outborns). The therapeutic procedures were surfactant administration in 22 newborns (13 outborns), nitric oxide in 12 newborns (7 outborns) and magnesium sulphate in four newborns (three outborns). The median length of ventilation was six days (inborn infants: four and half days; outborn infants: ten days) and the median length of oxygenation supply was ten days (inborn infants: four and half days; outborn infants: 15 days). The median length of stay was 13 days (inborn infants: 11 days; outborn infants: 16 days). One outborn infant died. conclusions: With this ventilation strategy, we have found no significant statistical differences between the two newborn groups, except for the length of oxygenation supply that was longer in the Outborn Group.
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