Ant-induced alopecia is a rare cause of acute, localized, nonscarring hair loss. It is most commo... more Ant-induced alopecia is a rare cause of acute, localized, nonscarring hair loss. It is most commonly caused by Pheidole pallidula ants, which can be found worldwide but are most common in Iran. The resulting alopecia can have many morphologic patterns (eg, patch, linear, nondiscrete) and thus ant-induced alopecia should be considered in the differential diagnosis for patients from endemic areas who present with new-onset localized hair loss. The condition is self-limited; however, patients should be evaluated for other more common causes of alopecia, especially in the absence of a convincing history.
We report a 30- year-old Iranian woman presenting with a red to yellowish, well demarcated, painl... more We report a 30- year-old Iranian woman presenting with a red to yellowish, well demarcated, painless exophytic and lobulated mass originating from the right hand side of the tongue. An excisional biopsy was obtained and it was diagnosed histopathologically as Kaposi's sarcoma by detecting atypical spindle cells with rare mitoses delineating blood-filled vascular slits.
... is an immunological disorder that affects many organ systems, including the gastrointestinal ... more ... is an immunological disorder that affects many organ systems, including the gastrointestinal tract, liver, lungs, and skin.1 It has been shown that sometimes GVHD is associated with leukoderma2,3 and a decreased number of melanocytic navi; however, no ... 3 Kang HY, Kang WH ...
Isotretinoin and its desirable effects have received tremendous attention in recent years by scie... more Isotretinoin and its desirable effects have received tremendous attention in recent years by scientists. This article reviews the evidence that decrease of insulin growth factor-1 is implicated as a novel mechanism of anti androgenic effect and its reported association with depression in some cases.
The Journal of clinical and aesthetic dermatology, 2015
Cutaneous metastases can have many different clinical presentations. They are seen in patients wi... more Cutaneous metastases can have many different clinical presentations. They are seen in patients with advanced malignant disease; however, they can be the initial manifestation of undetected malignancies. Inflammatory breast carcinoma is a rare and aggressive form of breast cancer that has a nonspecific appearance mimicking many benign conditions including mastitis, breast abscesses, and/or dermatitis. The authors report the case of a 40-year-old woman with inflammatory breast carcinoma presenting with violaceous papulovesicular lesions resembling lymphangioma circumscriptum and erythematous patches resembling erysipelas. These lesions represent two different types of cutaneous metastases, both of which were the initial signs of inflammatory breast carcinoma in the patient described herein. Skin biopsy of lesions confirmed invasive breast cancer and further prompted a work up for inflammatory breast carcinoma. This case demonstrates the importance of follow-up for all breast lesions, ...
Acta Dermatovenerologica Alpina Panonica Et Adriatica, Sep 1, 2009
... The first syndrome includes multiple apocrine hidradenomas associated with palmoplantar hyper... more ... The first syndrome includes multiple apocrine hidradenomas associated with palmoplantar hyperkeratosis, hypotrichosis, onychodystrophia, and hypodontia. ... Professor of Dermatology Department of Dermatology, Jondishapur University of Medical Sciences, Ahvaz, Iran, E-mail ...
Aloe vera Linne or aloe barbadensis Miller is a succulent from the Aloe family (400 different spe... more Aloe vera Linne or aloe barbadensis Miller is a succulent from the Aloe family (400 different species), a tropical plant which is easily grown in hot and dry climates and widely distributed in Asia, Africa and other tropical areas. The use of aloe vera is being promoted for a large variety of conditions. The aim of this systematic review was to summarize all dermatology-oriented in vitro and in vivo experiments and clinical trials on aloe vera preparations. Extensive literature search were carried out to identify all in vitro and in vivo studies as well as clinical trials on the subject. Data were extracted from these in a predefined standardized manner. Forty studies were located. The results suggest that oral administration of aloe vera in mice is effective on wound healing, can decrease the number and size of papillomas and reduce the incidence of tumors and leishmania parasitemia by >90% in the liver, spleen, and bone marrow. Topical application of aloe vera is not an effecti...
1, 25(OH) 2D3 (calcitriol) and its analogs, which are important regulators of calcium and bone me... more 1, 25(OH) 2D3 (calcitriol) and its analogs, which are important regulators of calcium and bone metabolism, have some non-calciotropic activities that include inhibition of cell proliferation and promotion of cell differentiation (1). Calcitriol is a potent antiproliferative agent against various tumor cells such as colorectal, breast and lung cancer, and also lymphoma and leukemia (2). It retards proliferation of several neoplastic cell types and acts as a chemopreventive agent in animal carcinogenesis (2,3). The antineoplastic effects of vitamin D3 derivatives are exerted at several steps in tumor progression (3). Nowadays, it has been shown that calcipotriol may exhibit antitumor activity against squamous cell carcinoma (SCC) (1,4,5). Further studies are needed to evaluate the preventive effect of calcipotriol in the development of SCC; nevertheless, below the authors would like to propose a novel hitherto unexplained mechanism for the probable calcitriol preventive effect against...
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2009
Dermatitis artefacta is a factitious dermatological disorder with many forms of presentation that... more Dermatitis artefacta is a factitious dermatological disorder with many forms of presentation that may occur on any part of the body. A diagnosis of dermatitis artefacta is often reached after rigorous and repeated investigations. Here we present the case of a 49-year-old single man complaining of a 4- month history of ulceration on the dorsal surface of the glans penis. In view of the unusual appearance of the lesion and the negative findings from clinical investigations, a diagnosis of dermatitis artefacta was made and the patient was referred for psychiatric evaluation. He was started on 20 mg/day of citalopram and titrated up to 40 mg/day by the 4th week, leading to complete remission in the following weeks. Thus, although rare, artefactual dermatitis should be considered in the differential diagnosis of unusual penile lesions.
Garlic (Allium sativum L. fam. Alliaceae) is one of the best-researched, best-selling herbal reme... more Garlic (Allium sativum L. fam. Alliaceae) is one of the best-researched, best-selling herbal remedies and is also commonly used for treating various health problems. Garlic is widely known for its biological properties and plays an important role as an antioxidant. The purpose of this review is to gather and summarize all dermatologic-oriented in vitro and in-vivo experiments and clinical trials on garlic preparations. Extensive literatures search was carried out and twenty three studies were included. The results suggest that oral administration of garlic is effective on immunologic properties, cutaneous microcirculation, protection against UVB and cancer treatment. Additionally, topical application of garlic extract can potentially be effective on psoriasis, alopecia areata, keloid scar, wound healing, cutaneous corn, viral and fungal infection, leishmaniasis, skin aging and rejuvenation. Clinical effectiveness of oral and topical garlic extract is not sufficiently and meticulousl...
Ant-induced alopecia is a rare cause of acute, localized, nonscarring hair loss. It is most commo... more Ant-induced alopecia is a rare cause of acute, localized, nonscarring hair loss. It is most commonly caused by Pheidole pallidula ants, which can be found worldwide but are most common in Iran. The resulting alopecia can have many morphologic patterns (eg, patch, linear, nondiscrete) and thus ant-induced alopecia should be considered in the differential diagnosis for patients from endemic areas who present with new-onset localized hair loss. The condition is self-limited; however, patients should be evaluated for other more common causes of alopecia, especially in the absence of a convincing history.
We report a 30- year-old Iranian woman presenting with a red to yellowish, well demarcated, painl... more We report a 30- year-old Iranian woman presenting with a red to yellowish, well demarcated, painless exophytic and lobulated mass originating from the right hand side of the tongue. An excisional biopsy was obtained and it was diagnosed histopathologically as Kaposi's sarcoma by detecting atypical spindle cells with rare mitoses delineating blood-filled vascular slits.
... is an immunological disorder that affects many organ systems, including the gastrointestinal ... more ... is an immunological disorder that affects many organ systems, including the gastrointestinal tract, liver, lungs, and skin.1 It has been shown that sometimes GVHD is associated with leukoderma2,3 and a decreased number of melanocytic navi; however, no ... 3 Kang HY, Kang WH ...
Isotretinoin and its desirable effects have received tremendous attention in recent years by scie... more Isotretinoin and its desirable effects have received tremendous attention in recent years by scientists. This article reviews the evidence that decrease of insulin growth factor-1 is implicated as a novel mechanism of anti androgenic effect and its reported association with depression in some cases.
The Journal of clinical and aesthetic dermatology, 2015
Cutaneous metastases can have many different clinical presentations. They are seen in patients wi... more Cutaneous metastases can have many different clinical presentations. They are seen in patients with advanced malignant disease; however, they can be the initial manifestation of undetected malignancies. Inflammatory breast carcinoma is a rare and aggressive form of breast cancer that has a nonspecific appearance mimicking many benign conditions including mastitis, breast abscesses, and/or dermatitis. The authors report the case of a 40-year-old woman with inflammatory breast carcinoma presenting with violaceous papulovesicular lesions resembling lymphangioma circumscriptum and erythematous patches resembling erysipelas. These lesions represent two different types of cutaneous metastases, both of which were the initial signs of inflammatory breast carcinoma in the patient described herein. Skin biopsy of lesions confirmed invasive breast cancer and further prompted a work up for inflammatory breast carcinoma. This case demonstrates the importance of follow-up for all breast lesions, ...
Acta Dermatovenerologica Alpina Panonica Et Adriatica, Sep 1, 2009
... The first syndrome includes multiple apocrine hidradenomas associated with palmoplantar hyper... more ... The first syndrome includes multiple apocrine hidradenomas associated with palmoplantar hyperkeratosis, hypotrichosis, onychodystrophia, and hypodontia. ... Professor of Dermatology Department of Dermatology, Jondishapur University of Medical Sciences, Ahvaz, Iran, E-mail ...
Aloe vera Linne or aloe barbadensis Miller is a succulent from the Aloe family (400 different spe... more Aloe vera Linne or aloe barbadensis Miller is a succulent from the Aloe family (400 different species), a tropical plant which is easily grown in hot and dry climates and widely distributed in Asia, Africa and other tropical areas. The use of aloe vera is being promoted for a large variety of conditions. The aim of this systematic review was to summarize all dermatology-oriented in vitro and in vivo experiments and clinical trials on aloe vera preparations. Extensive literature search were carried out to identify all in vitro and in vivo studies as well as clinical trials on the subject. Data were extracted from these in a predefined standardized manner. Forty studies were located. The results suggest that oral administration of aloe vera in mice is effective on wound healing, can decrease the number and size of papillomas and reduce the incidence of tumors and leishmania parasitemia by >90% in the liver, spleen, and bone marrow. Topical application of aloe vera is not an effecti...
1, 25(OH) 2D3 (calcitriol) and its analogs, which are important regulators of calcium and bone me... more 1, 25(OH) 2D3 (calcitriol) and its analogs, which are important regulators of calcium and bone metabolism, have some non-calciotropic activities that include inhibition of cell proliferation and promotion of cell differentiation (1). Calcitriol is a potent antiproliferative agent against various tumor cells such as colorectal, breast and lung cancer, and also lymphoma and leukemia (2). It retards proliferation of several neoplastic cell types and acts as a chemopreventive agent in animal carcinogenesis (2,3). The antineoplastic effects of vitamin D3 derivatives are exerted at several steps in tumor progression (3). Nowadays, it has been shown that calcipotriol may exhibit antitumor activity against squamous cell carcinoma (SCC) (1,4,5). Further studies are needed to evaluate the preventive effect of calcipotriol in the development of SCC; nevertheless, below the authors would like to propose a novel hitherto unexplained mechanism for the probable calcitriol preventive effect against...
Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2009
Dermatitis artefacta is a factitious dermatological disorder with many forms of presentation that... more Dermatitis artefacta is a factitious dermatological disorder with many forms of presentation that may occur on any part of the body. A diagnosis of dermatitis artefacta is often reached after rigorous and repeated investigations. Here we present the case of a 49-year-old single man complaining of a 4- month history of ulceration on the dorsal surface of the glans penis. In view of the unusual appearance of the lesion and the negative findings from clinical investigations, a diagnosis of dermatitis artefacta was made and the patient was referred for psychiatric evaluation. He was started on 20 mg/day of citalopram and titrated up to 40 mg/day by the 4th week, leading to complete remission in the following weeks. Thus, although rare, artefactual dermatitis should be considered in the differential diagnosis of unusual penile lesions.
Garlic (Allium sativum L. fam. Alliaceae) is one of the best-researched, best-selling herbal reme... more Garlic (Allium sativum L. fam. Alliaceae) is one of the best-researched, best-selling herbal remedies and is also commonly used for treating various health problems. Garlic is widely known for its biological properties and plays an important role as an antioxidant. The purpose of this review is to gather and summarize all dermatologic-oriented in vitro and in-vivo experiments and clinical trials on garlic preparations. Extensive literatures search was carried out and twenty three studies were included. The results suggest that oral administration of garlic is effective on immunologic properties, cutaneous microcirculation, protection against UVB and cancer treatment. Additionally, topical application of garlic extract can potentially be effective on psoriasis, alopecia areata, keloid scar, wound healing, cutaneous corn, viral and fungal infection, leishmaniasis, skin aging and rejuvenation. Clinical effectiveness of oral and topical garlic extract is not sufficiently and meticulousl...
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