Book Reviews by Ali Alkhafaji
Bu kitap iş ve işsizlik oranının artması ve nedenleri hakkında konuşmaktadır.
Bu bölüm postmodern organizasyonun nasıl göründüğüyle alakalıdır.
Bu bölüm postmodern organizasyonun nasıl göründüğüyle alakalıdır.
Papers by Ali Alkhafaji
The present correlation showed a good agreement with the available experimental data of the nucle... more The present correlation showed a good agreement with the available experimental data of the nucleate pool boiling heat transfer coefficient from the literature with a total absolute mean errors of (8%) and (9%) for the low finned and Gewa-T surfaces respectively.
Critical Care Medicine, Sep 1, 2009
Anesthesia and Analgesia, Jun 1, 2002
We report a case of toxicity from the drug solvent propylene glycol resulting from prolonged, lar... more We report a case of toxicity from the drug solvent propylene glycol resulting from prolonged, large-dose lorazepam infusion. The case is unusual in that toxicity developed during continuous veno-venous hemofiltration with dialysis, a renal replacement therapy that should been have been effective at eliminating the chemical and its metabolites.
Chest, 2006
Rady, Mohamed Y.
Critical Care Medicine, Jul 1, 2001
To report a case of fatal hyperkalemia owing to succinylcholine administration in a patient with ... more To report a case of fatal hyperkalemia owing to succinylcholine administration in a patient with mucositis secondary to chemotherapy. Case report. Adult intensive care unit (ICU) at Dartmouth-Hitchcock Medical Center. One patient with mucositis secondary to chemotherapy. A 37-yr-old female with recently diagnosed acute myelogenous leukemia was admitted to the ICU with mental status changes and progressive dyspnea requiring intubation and mechanical ventilation. Before ICU admission, the patient had suffered from painful mucositis causing severe dysphagia and bleeding, which was thought to be the result of chemotherapy. By the 10th ICU day, the patient's respiratory and mental status improved and the patient was successfully extubated. However, 8 hrs after extubation, she gradually developed severe respiratory distress, requiring reintubation and mechanical ventilation. The patient was given 14 mg of etomidate and 100 mg of succinylcholine intravenously. Immediately after the intubation, she suffered cardiac arrest. Her serum potassium level was 13.1 mEq/L and HCO3- was 16 mEq/L. The resuscitation attempt was unsuccessful, and the patient was pronounced dead. Oral mucositis is a frequent and potentially severe complication of cancer chemotherapy. We believe that mucositis was a contributing factor to this case of fatal hyperkalemia after administration of succinylcholine, with a mechanism similar to that reported with thermal injury. Only nondepolarizing muscle relaxants should be used in patients who are at risk for mucositis. Mucositis should be added to the list of conditions in which succinylcholine is contraindicated.
Gastroenterology, May 31, 2011
Critical Care and Resuscitation Journal of the Australasian Academy of Critical Care Medicine, Sep 1, 2013
Despite efforts to increase organ donation, there remain critical shortages in organ donors and o... more Despite efforts to increase organ donation, there remain critical shortages in organ donors and organs procured per donor. Our trial is a large-scale, multicentre, randomised controlled trial in brain-dead donors, to compare protocolised care (using minimally invasive haemodynamic monitoring) with usual care. We describe the study design and discuss unique aspects of doing research in this population. Our study will randomise brain-dead patients to protocolised or usual care. The primary end point is the number of organs transplanted per donor. Secondary end points include number of transplantable organs per donor, recipient 6-month hospital-free survival time, and the relationship between the level of interleukin-6 and the number and usability of organs transplanted. The primary analysis will be an intention-to-treat analysis; secondary analyses include modified intention-to-treat and as-treated analyses. The study will also compare the ratio of observed to expected number of organs transplanted per donor, by treatment arm, as a secondary end point. Preplanned subgroup analyses include restriction to extended criteria donors, and donors older or younger than 65 years. Several unique challenges for study design and execution can be seen in our trial, and it should generate results that will inform and influence the fields of organ donation and transplantation.
Transplantation Journal, 2010
Bedside Procedures in the ICU, 2011
Journal of Neuro-Oncology, 2015
Functional independence in glioblastoma (GBM) patients is a key factor in measuring the quality o... more Functional independence in glioblastoma (GBM) patients is a key factor in measuring the quality of life. Progression free survival (PFS) and overall survival (OS) have been largely described. However, the evolution over time of the performance status during the patients' life remains understudied. We thus studied the time to loss of functional independence as assessed by a Karnosky Performance Status (KPS) below 70 % in GBM patients. We analysed all GBM patients treated in our institution between 2008 and 2013 and meeting the following criteria: age >18 years, supratentorial location, post-surgical KPS ≥ 70 %, initially treated with concomitant radiotherapy (RT) and Temozolomide. Within the 84 patients studied, the median PFS was 9 months and the median OS was 18.7 months. The median survival time with functional independence (KPS ≥ 70 %) was 14.5 months. On average, the patients spent 73 % of their lifespan with a KPS ≥ 70 %. Surgical resection and low steroid dosage were statistically associated with increased survival time with KPS ≥ 70 % (p = 0.015 and p = 0.03, respectively). Sixty-two (62) patients received one or several lines of chemotherapy at recurrence. Under treatment with Bevacizumab (42 Bev-based regimens), radiological responses were seen in 35 % and improvement in KPS occurred in 24 % whereas no response and rare improvement of KPS (3 %) were seen with other type of chemotherapy (97 non Bev-based regimens). In GBM patients, median survival with KPS ≥ 70 % largely exceeds PFS. Surgical resection and low steroids dosage at RT-onset appeared as good prognosis factors for survival with functional independence.
Transfusion Alternatives in Transfusion Medicine, 2003
Journal of Critical Care, 2008
Journal of Cardiothoracic and Vascular Anesthesia, 2007
... MN. ‡, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, May... more ... MN. ‡, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN. §, Mayo Clinic College of Medicine, Jacksonville, FL. Available online 6 March 2007. ...
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Book Reviews by Ali Alkhafaji
Papers by Ali Alkhafaji