Hamid Merchant

University of Huddersfield, School of Applied Sciences, Faculty Member

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Dr Merchant joined the University of Huddersfield in October 2013 and is currently working as a Subject Lead in Pharmacy and Course Leader for the Postgraduate Pharmacy Suite. He has a formulation sciences background with extensive experience both from industry and academia. He has a particular interest in drug delivery research at the interface of gastroenterology and publishes regularly in peer-reviewed journals. He is an overseas qualified and registered pharmacist. His clinical knowledge and expertise in pharmaceutics helps students to understand the clinical and therapeutic principles underpinning the science of dosage form design.Before joining Huddersfield in November 2013, he was a postdoctoral fellow at the University College London (UCL), where he investigated various technologies for drug delivery into gastrointestinal tract and offered technical support and expert advice to collaborators and clients from academia and industry on various formulation and drug delivery aspects. One of his postdoc assignments at UCL was to develop a novel formulation for colonic delivery of statins for an emerging pharmaceutical company in UK. During his time at UCL (Nov 2007 to Nov 2012), he has also developed novel in-vitro solutions for assessment of pharmaceutical and neutraceutial products in physiologically relevant conditions. He developed innovative strategies for exploiting physiological bicarbonate buffers for dissolution testing and devised an Auto pH SystemTM – a robust instrumentation and dynamic dissolution media (PCT/GB2013/051145) employing physiological bicarbonate buffers simulating the aboral changes in gastrointestinal pH while dosage form transits down the gut. Hamid has also won a proof of concept award from UCL Business to further the technology.Hamid was associated with Abbott Laboratories Ltd from December 2002 to November 2007 and served in various capacities such as quality, formulation, new product development, continuous improvement and project management. He has been involved in peer review of various research journals and is a Managing Editor of the British Journal of Pharmacy (BJPharm). Hamid is a Fellow of the Higher Education Academy (HEA UK), a member of the Royal Pharmaceutical Society of Great Britain (RPSGB), American Association of Pharmaceutical Scientists (AAPS), Controlled Release Society (CRS) and Academy of Pharmaceutical Sciences, Great Britain (APS).Dr Merchant has a Pharmacy degree (BPharm) with a Masters in Pharmaceutics (MPharm) from University of Karachi and a PhD in Pharmaceutical Formulations from the University College London (UCL). He also have a PGD in Quality Management from NED and a PGCert in Higher Education from Huddersfield.

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Physiology of the Gastrointestinal System

Elsevier eBooks, 2018

Gastrointestinal (GI) physiology describes the normal functions of the digestive tract, particula... more Gastrointestinal (GI) physiology describes the normal functions of the digestive tract, particularly that of its hollow organs. Within the oropharynx, oesophagus, stomach, small bowel, colon, and rectum, nutrient solids and fluids are ingested, propelled, mixed, digested, and absorbed while non-absorbable materials are stored and excreted. Critical to the digestive process are the exocrine secretions of the pancreas, liver, and gastrointestinal mucosae. These secretions break and dissolve the large, complex, ingested molecules of food into smaller compounds, which are then ready for absorption into the intestinal epithelium and its circulation. The gastrointestinal wall embedding transporters and mucosal enzymes critically controls the absorption of nutrition and exogenous substances, such as drugs, across GI mucosa. The chapter gives an overview of the three major physiological functions of the gastrointestinal system, i.e., are motility, secretion, and digestion/absorption, influencing the fate of nutrition and pharmaceuticals administered into the GI tract.

Mortality risk in patients infected with SARS-CoV-2 of the lineage B.1.1.7 in the UK

Journal of Infection, Jul 1, 2021

A leap towards enforcing medicines prescribing by generic names in low- and middle-income countries (LMICs): pitfalls, limitations, and recommendations for local drug regulatory agencies

Journal of Pharmaceutical Policy and Practice, Dec 22, 2022

The Drug Regulatory Authority of Pakistan (DRAP) in response to the public outcry on increasing m... more The Drug Regulatory Authority of Pakistan (DRAP) in response to the public outcry on increasing medicines prices in the country issued notifications to direct healthcare professionals to prescribe medicines with their generic names. Like DRAP, many regulators in the low-and middle-income countries (LMICs) are also inspiring from the west to legally enforce generic prescribing in a bid to reduce the out-of-pocket public expenditures. However, there are pitfalls in the LMICs drug regulatory framework, which if left unaddressed can severely jeopardise the foreseen benefits of medicines prescribing by generic names. This article critically appraises the impact of prescribing by generic names regulations in LMICs and highlights the key considerations that are vital to address before legally enforcing generic prescribing. The ethics, regulatory compliance, and good governance are the key to success; better generics for a better tomorrow.

Hamid Merchant

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