Fernando Bozza

Instituto Leônidas e Maria Deane - Fiocruz, Programa de Pós-Graduação - PPGVIDA, Faculty Member

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Fred C. G. J. Sweep

Radboudumc Nijmegen - The Netherlands

massimo gion

Robin Prescott

University of Edinburgh

Brescia University

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Papers by Fernando Bozza

Involvement of CC-chemokine receptor 2 in sepsis: focus on cognitive impairment

by Patrícia A L D L Reis and Fernando Bozza

Critical Care, 2013

Staging of locally advanced breast cancer and the prediction of response to neoadjuvant chemotherapy: complementary role of scintimammography and 18F-FDG PET/CT

by Anna Cervino and Fernando Bozza

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., Jan 12, 2014

The primary end--point of the study was to established the role of sestamibi scintimammography an... more The primary end--point of the study was to established the role of sestamibi scintimammography and PET/CT findings in locally advanced breast cancer (LABC) before neoadjuvant systemic therapy (NST) in different histological subtypes. The secondary end--point was to determine the role of FDG PET/CT as multi drug resistance marker. METHODS:From January 2012, we prospectively enrolled 51 consecutive women (median age: 49 years;; range: 27--76 yrs) with a biopsy--proven LABC. All patients underwent both sestamibi scintimammography and FDG PET/CT within one week before to start NST. Both examinations were qualitatively and semiquantitatively analysed. For scintimammography we calculated the tumor to background ratio (T/B) and the most intense uptake of the tumor to background ratio (I/B) according the following formula: T/B=[cntsT--cntsB]/ [cntsB] and I/B [cntsI--cntsB]/ [cntsB]. Furthermore, the percentage washout index (WO) for T and I were obtained, according to: WOT,I= [cntsT,I]early...

Influence of age and menopausal status on pathologic and biologic features of breast cancer

Breast (Edinburgh, Scotland), 2000

The distribution of the main prognostic factors in different age groups was evaluated in 1226 pat... more The distribution of the main prognostic factors in different age groups was evaluated in 1226 patients operated on for primary breast cancer, in order to identify those influenced by age and/or menopausal status. Patients were divided into the following groups: 1) 40 years of age and under; 2) premenopausal over 40 years of age; 3) postmenopausal under 75 years of age and 4) 75 years of age and over. Our findings showed that the youngest patients had the worst prognostic pattern, which improves as age increases and is the best in patients over 75 years of age. Some of the parameters investigated (tumour size, histologic and nuclear grade, tumour infiltrating lymphocytes, p53 and Ki 67) were found to be influenced by age, some (necrosis and oestrogen receptors) were influenced by menopausal status and/or age, some (vascular invasion, ploidy, S-phase and progesterone receptors) showed significant differences in different age groups but there was no consistent relation with patient age...

Fernando Bozza

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