Stephen Busby
Stephen Busby FRS | |
|---|---|
| Education | University of Cambridge (B.A. 1972), University of Oxford (D.Phil. 1975) |
| Known for | Molecular mechanisms controlling gene expression in bacteria |
| Scientific career | |
| Fields | Biochemistry |
| Institutions | Pasteur Institute, University of Birmingham |
| Doctoral advisor | George Radda |
| Other academic advisors | Rex Richards |
Stephen Busby FRS[1][2] is a British biochemist, and professor at the University of Birmingham.[3] His research is concerned with the molecular mechanisms controlling gene expression in bacteria, especially regulation of transcription initiation in Escherichia coli.
Career
[edit]Stephen Busby started his career working for several years at the Pasteur Institute in Paris,[4] where he remained until moving to the University of Birmingham in 1983.
After obtaining his doctorate at Oxford, he worked in the laboratory of George Radda, in collaboration with Rex Richards, on nuclear magnetic resonance of metabolites.[5] Subsequently his interest moved towards reguatory mechanisms and transcription in bacteria,[6] participating in making recommendations about transctiption initiation,[7] and developing new methods for studying recombinant protein production.[8]
Administrative activities
[edit]Busby was Head of the School of Biosciences at the University of Birmingham between 2012 and 2016. Over much of the same period he was chair of the Biochemical Society (2011–2016). He has been a Member of BBSRC Committee E (Fellowships).
References
[edit]- ^ "Professor Stephen Busby FRS".
- ^ The description reads as follows: He has made big contributions to our understanding of the process of gene transcription in bacteria and how it is regulated. In particular, his recent work has focused on pathogenic bacteria and the genes they possess that are responsible for infection.
- ^ "Professor Steve Busby".
- ^ "FEMS Expert: Prof Steve Busby".
- ^ Hoult, D.I.; Busby, S.J.; Gadian, D. G.; Radda, G.K.; Richards, R. E.; Seeley, P.J. (1974). "Observation of tissue metabolites using 31P nuclear magnetic resonance". Nature. 252 (5481): 285–287. doi:10.1038/252285a0.
- ^ Browning, Douglas F.; Busby, S.J. (2004). "The regulation of bacterial transcription initiation". Nat. Rev. Microbiol. 2 (1): 57–65. doi:10.1038/nrmicro787.
- ^ Mejía-Almonte, Citlalli; Busby, Stephen J.W.; Wade, Joseph T.; van Helden, Jacques; Arkin, Adam P.; Stormo, Gary D.; Eilbeck, Karen; Palsson, Bernhard O; Galagan, James E.; Collado-Vides, Julio (2020). "Redefining fundamental concepts of transcription initiation in bacteria". Nat. Rev. Genet. 21 (11): 699–714. doi:10.1038/s41576-020-0254-8. PMC 7990032. PMID 32665585.
- ^ Hothersall, J.; Osgerby, A.; Godfrey, R.; Overton, T.; Richards, R. E. "New vectors for urea-inducible recombinant protein production". New Biotechnol. 72: 89–96. doi:10.1016/j.nbt.2022.10.003.
External links
[edit]- http://www.jic.ac.uk/corporate/about/organisation/scienceandimpactadvisoryboard.html
- http://www.astbury.leeds.ac.uk/Intro/SAB.html
- https://web.archive.org/web/20120426002158/http://www2.bioch.ox.ac.uk/oubs/pastevents.php
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