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N-acetyltransferase 1

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NAT1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNAT1, AAC1, MNAT, NAT-1, NATI, N-acetyltransferase 1, N-acetyltransferase 1 (arylamine N-acetyltransferase)
External IDsOMIM: 108345; MGI: 109201; HomoloGene: 37329; GeneCards: NAT1; OMA:NAT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001168577
NM_010874

RefSeq (protein)

NP_001162049
NP_035004

Location (UCSC)Chr 8: 18.17 – 18.22 MbChr 8: 67.95 – 67.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

N-acetyltransferase 1 (arylamine N-acetyltransferase) is a protein that in humans is encoded by the NAT1 gene.[5]

This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat NAT2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171428Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051147Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: N-acetyltransferase 1 (arylamine N-acetyltransferase)". Retrieved 2012-01-27.

Further reading

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