SpoIVB peptidase (EC 3.4.21.116, sporulation factor IV B protease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
| SpoIVB peptidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.116 | ||||||||
| CAS no. | 296241-18-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- Self-cleaves Val52-Asn53, Ala62-Phe63 and Val74-Thr75 at the N-terminus of SpoIVB
This enzyme participates in gene expression during the later stages of spore formation in Bacillus subtilis.
References
edit- ^ Wakeley PR, Dorazi R, Hoa NT, Bowyer JR, Cutting SM (June 2000). "Proteolysis of SpolVB is a critical determinant in signalling of Pro-sigmaK processing in Bacillus subtilis". Molecular Microbiology. 36 (6): 1336–48. doi:10.1046/j.1365-2958.2000.01946.x. PMID 10931284.
- ^ Hoa NT, Brannigan JA, Cutting SM (July 2001). "The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions". Journal of Bacteriology. 183 (14): 4364–73. doi:10.1128/jb.183.14.4364-4373.2001. PMC 95327. PMID 11418578.
- ^ Hoa NT, Brannigan JA, Cutting SM (January 2002). "The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases". Journal of Bacteriology. 184 (1): 191–9. doi:10.1128/jb.184.1.191-199.2002. PMC 134772. PMID 11741860.
- ^ Dong TC, Cutting SM (September 2003). "SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of Pro-sigmaK in Bacillus subtilis". Molecular Microbiology. 49 (5): 1425–34. doi:10.1046/j.1365-2958.2003.03651.x. PMID 12940997.
External links
edit- SpoIVB+peptidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
