SPATA5

Spermatogenesis-associated protein 5 is a protein that in humans is encoded by the SPATA5 gene.

SPATA5
Identifiers
Aliases	SPATA5, AFG2, SPAF, EHLMRS, spermatogenesis associated 5, NEDHSB
External IDs	OMIM: 613940; MGI: 1927170; HomoloGene: 56920; GeneCards: SPATA5; OMA:SPATA5 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) Band 4q28.1 Start 122,923,070 bp End 123,319,433 bp
Gene location (Mouse) Chr. Chromosome 3 (mouse) Band 3|3 B Start 37,474,045 bp End 37,633,245 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tendon of biceps brachii Achilles tendon palpebral conjunctiva gonad testicle bone marrow cells ventricular zone internal globus pallidus sural nerve epithelium of colon Top expressed in spermatocyte primitive streak seminiferous tubule primary oocyte spermatid Gonadal ridge genital tubercle tail of embryo epiblast motor neuron More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding ATP binding ATPase activity hydrolase activity Cellular component cytoplasm mitochondrion Biological process multicellular organism development cell differentiation brain development spermatogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 166378 57815 Ensembl ENSG00000145375 ENSMUSG00000027722 UniProt Q8NB90 Q3UMC0 RefSeq (mRNA) NM_145207 NM_001317799 NM_001345856 NM_001163511 NM_021343 NM_001310473 RefSeq (protein) NP_001304728 NP_001332785 NP_660208 NP_001156983 NP_001297402 NP_067318 Location (UCSC) Chr 4: 122.92 – 123.32 Mb Chr 3: 37.47 – 37.63 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Liu Y, Black J, Kisiel N, Kulesz-Martin MF (2000). "SPAF, a new AAA-protein specific to early spermatogenesis and malignant conversion". Oncogene. 19 (12): 1579–88. doi:10.1038/sj.onc.1203442. PMID 10734318.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nature Genetics. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.